- Psychosomatic Disorders and Their Treatments
- Schizophrenia research and treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health and Psychiatry
- Mental Health Research Topics
- Child and Adolescent Psychosocial and Emotional Development
- Paranormal Experiences and Beliefs
- Mental Health Treatment and Access
- Personality Disorders and Psychopathology
- Body Image and Dysmorphia Studies
- Sleep and related disorders
- COVID-19 and Mental Health
- Film in Education and Therapy
- Suicide and Self-Harm Studies
- Psychotherapy Techniques and Applications
- Empathy and Medical Education
- Traumatic Brain Injury Research
- Genetic Associations and Epidemiology
- Humor Studies and Applications
- Infant Development and Preterm Care
- Critical Race Theory in Education
- Bipolar Disorder and Treatment
- Genetic Neurodegenerative Diseases
- Infant Health and Development
- Eating Disorders and Behaviors
University of Birmingham
2022-2025
Birmingham and Solihull Mental Health NHS Foundation Trust
2025
University of Oxford
2013-2023
Warneford Hospital
2014-2023
Oxford Health NHS Foundation Trust
2016-2023
University of Manchester
2016
Institució Catalana de Recerca i Estudis Avançats
2016
University College London
2016
King's College London
2015
Worry might be a contributory causal factor in the occurrence of persecutory delusions patients with psychotic disorders. Therefore we postulated that reducing worry cognitive behaviour therapy (CBT) would reduce delusions.For our two-arm, assessor-blinded, randomised controlled trial (Worry Intervention Trial [WIT]), recruited aged 18-65 years persistent but non-affective psychosis from two centres: Oxford Health National Service (NHS) Foundation Trust (Oxford, UK) and Southern NHS...
Background Persecutory delusions may be unfounded threat beliefs maintained by safety-seeking behaviours that prevent disconfirmatory evidence being successfully processed. Use of virtual reality could facilitate new learning. Aims To test the hypothesis enabling patients to predictions persecutory in social environments with dropping (virtual cognitive therapy) would lead greater delusion reduction than exposure alone exposure). Method Conviction and distress a real-world situation were...
Research has shown that paranoia may directly build on negative ideas about the self. Feeling inferior can lead to of vulnerability. The clinical prediction is decreasing self cognitions will reduce paranoia.Thirty patients with persistent persecutory delusions were randomised receive brief CBT in addition standard care or (ISRCTN06118265). six session intervention was designed decrease negative, and increase positive, cognitions. Assessments at baseline, 8 weeks (posttreatment) 12 carried...
BackgroundThere is a large clinical need for improved treatments patients with persecutory delusions. We aimed to test whether new theoretically driven cognitive therapy (the Feeling Safe Programme) would lead reductions in delusions, above non-specific effects of therapy. also treatment effect mechanisms.MethodsWe did parallel, single-blind, randomised controlled trial the Programme against befriending same therapists persistent delusions context non-affective psychosis diagnoses. Usual...
Dissociative experiences, traditionally studied in relation to trauma and PTSD, may be important phenomena across many different psychological conditions, including as a contributory causal factor for psychotic experiences. In this study, the aim was explore, using network approaches, how dissociative experiences taking form of Felt Sense Anomaly (FSA) relate both common mental health conditions 6941 individuals from general population completed online assessments FSA-dissociation,...
Background Persecutory delusions are a key psychotic experience. A reasoning style known as ‘jumping to conclusions’ (JTC) – limited information gathering before reaching certainty in decision making has been identified contributory factor the occurrence of delusions. The cognitive processes that underpin JTC need be determined order develop effective interventions for In current study two alternative perspectives were tested: partially results from impairment information-processing...
To determine the prevalence of suicidal ideation and behaviour - their correlates in patients with persecutory delusions. 110 delusions context non-affective psychosis were assessed for thoughts behaviours over past month. Symptom psychological assessments also completed. The severity was: no (n = 26, 23.6%); wish to be dead 21, 19.1%); nonspecific active 14, 12.7%); methods but intent 29, 26.4%); specific plan 13, 11.8%); 7, 6.4%). In month, five (4.5%) had made an actual, interrupted, or...
Sleep disturbance is common and problematic for young people at ultra-high risk of psychosis. disruption a contributory causal factor in the occurrence mental health problems, including psychotic experiences, anxiety, depression. The implication that treating sleep problems might have additional benefits on outcomes individuals high risk. present study had two aims: first, to establish feasibility acceptability randomised controlled trial treat with aim reducing experiences psychosis;...
Dissociation is associated with clinical severity, increased risk of suicide and self-harm, disproportionately affects adolescents young adults. Whilst evidence indicates multiple factors contribute to dissociative experiences, a multi-factorial explanation for dissociation has yet be achieved. We used regression investigate the relative influence five plausible (childhood trauma, loneliness, marginalisation, socio-economic status, everyday stress), machine learning generate tentative...
Introduction: Dissociation is associated with clinical severity, increased risk of suicide and self-harm, disproportionately affects adolescents young adults. Whilst evidence indicates multiple factors contribute to dissociative experiences, a multifactorial explanation for dissociation has yet be achieved. Methods: We used regression investigate the relative influence five plausible (childhood trauma, loneliness, marginalisation, socio-economic status, everyday stress), machine learning...
ObjectiveResearch indicates higher prevalence of dissociative experiences in adolescents than adults. However, the exact phenomenology and underlying mechanisms dissociation adolescence have yet to be clarified. The current study explores presentation of, possible psychological factors underlying, this population.MethodTwo online self-report surveys captured data from 3076 aged 13 18 years. Participants completed Černis Felt Sense Anomaly (ČEFSA) scale felt sense anomaly-type dissociation,...
BackgroundDissociative experiences are common transdiagnostically, and particularly prevalent in psychosis. Such have long been under-recognised routine clinical practice, despite evidence that dissociation is related to complexity increased risk of self-harm suicidality. Adopting a symptom-specific, targeted approach conceptualisation intervention may help improve outcomes. AimsThe base for psychological treatments targeting building, but training guidance clinicians remains sparse. This...
Background: Paranoia may build directly upon negative thoughts about the self. There have been few direct experimental tests of this hypothesis. Aims: The aim study was to test immediate effects manipulating self-esteem in individuals vulnerable paranoia. Method: A two condition cross-over conducted. participants were 26 males reporting paranoid ideation past month. Each participant experienced a neutral immersive virtual reality (VR) social environment twice. Before VR received low...
Worry has traditionally been considered in the study of common emotional disorders such as anxiety and depression, but recent studies indicate that worry may be a causal factor occurrence persistence persecutory delusions. The effect on processes associated with psychosis not tested. aim was to examine short-term effects bout three cognitive typically markers psychosis: working memory, jumping conclusions, anomalous internal experience. Sixty-seven patients delusions context non-affective...
Worry may be common in patients with paranoia and a contributory causal factor the occurrence of delusions. A number psychological mechanisms have been linked to worry emotional disorders but these are yet investigated psychosis. The primary aim study was test links between five main - perseverative thinking, catastrophizing, stop rules, metacognitive beliefs, intolerance uncertainty cognitive style persecutory delusions.One hundred fifty delusions completed assessments paranoia, worry,...
Despite its long history, dissociation remains under-recognised clinically, partly due to difficulties identifying dissociative symptoms. Qualitative research may support recognition by providing a lived experience perspective. In non-affective psychosis, identification of be particularly important given that such experiences have been implicated development and maintenance. Therefore, this study aimed understand in the context psychosis: what it is like dissociation; impact might have;...
Background: Many patients do not respond adequately to current pharmacological or psychological treatments for psychosis. Persistent persecutory delusions are common in clinical services, and cause considerable patient distress impairment. Our aim has been build a new translational personalized treatment, with the potential wide use, that leads high rates of recovery persistent delusions. We have developing, evaluating individually, brief modular interventions, each targeting key causal...
Abstract Background The cognitive process of worry, which keeps negative thoughts in mind and elaborates the content, contributes to occurrence many mental health disorders. Our principal aim was develop a straightforward measure general problematic worry suitable for research clinical treatment. secondary specifically concerning paranoid fears. Methods An item pool past month evaluated 250 non-clinical individuals 50 patients with psychosis treatment trial. Exploratory factor analysis...
A large number of mechanisms, many relating to the processing affect, have been proposed cause dissociation. The aim this study was use network analyses identify psychological processes most closely connected with 'felt sense anomaly' dissociative experiences. Both an undirected model and a partially directed were estimated using data from 6161 general population respondents collected online. networks used relationships between dissociation ten candidate mechanisms: cognitive appraisals,...
Background: Ruminative negative thinking has typically been considered as a factor maintaining common emotional disorders and recently shown to maintain persecutory delusions in psychosis. The Perseverative Thinking Questionnaire (PTQ) (Ehring et al., 2011) is transdiagnostic measure of ruminative that shows promise “content-free” thinking. Aims: PTQ not previously studied psychosis patient group. In this study we report for the first time on psychometric properties Ehring al.'s such Method:...
Abstract Background Schizophrenia patients are typically found to have low IQ both pre- and post-onset, in comparison the general population. However, a subgroup of displays above average pre-onset. The nature these patients’ illness its relationship typical schizophrenia is not well understood. current study sought investigate symptom profile high-IQ patients. Methods We identified 29 exceptionally high pre-morbid intelligence (mean estimated quotient (IQ) 120), whom around half also showed...