- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Hip disorders and treatments
- Elbow and Forearm Trauma Treatment
- Orthopaedic implants and arthroplasty
- Atrial Fibrillation Management and Outcomes
- Cardiomyopathy and Myosin Studies
- Orthopedic Surgery and Rehabilitation
- Trauma Management and Diagnosis
- Muscle Physiology and Disorders
- Cardiac Valve Diseases and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Anesthesia and Pain Management
- Spine and Intervertebral Disc Pathology
- Cardiac Arrhythmias and Treatments
- Reproductive Health and Contraception
- Malaria Research and Control
- Nerve Injury and Rehabilitation
- Inhalation and Respiratory Drug Delivery
- Cellular Mechanics and Interactions
- Global Maternal and Child Health
- Sexual function and dysfunction studies
- Sarcoma Diagnosis and Treatment
- Iron Metabolism and Disorders
- Adolescent Sexual and Reproductive Health
Clínica Santa María
2017-2023
Northwest Vista College
2020-2022
Berkeley City College
2022
Clinica Santa Maria
2018
Universidad de Los Andes, Chile
2018
Universidad Cooperativa de Colombia
2016
Marymount University
2016
Clínica CES
2007-2014
University of British Columbia
2004-2013
Hospital Universitario Nuestra Señora de Candelaria
2013
Smooth muscle cells line the walls of hollow organs and control organ dimension mechanical function by generating force changing length. Although significant progress has been made in our understanding molecular mechanism actomyosin interaction that produces sliding actin (thin) myosin (thick) filaments smooth muscle, sarcomeric structure akin to striated which allows contractile be translated into cell shortening yet elucidated. Here we show evidence from porcine airway supports a model...
Background: Surgical treatment of distal diaphyseal humerus fractures (DDHF) minimally invasive plate osteosynthesis (MIPO) has gained popularity among orthopedic surgeons as it causes less soft-tissue disruption associated with other open approaches; however, the iatrogenic radial nerve injury is still a concern. Recently, novel technique for MIPO through anterior approach and anterolateral fixation was proposed an alternative to reduce risk damage. Aims: To determine mid-to-long-term...
Actin polymerization as part of the normal smooth muscle response to various stimuli has been reported. The actin dynamics are believed be necessary for cytoskeletal remodeling in its adaptation external stress and strain maintenance optimal contractility. We have shown our previous studies airway that myosins polymerized contractile activation well at longer cell lengths. postulated same could elicited from actins under conditions. In present study, filament formation was quantified...
OBJECTIVE: To evaluate if the application of a negative-pressure therapy system (Prevena Incision Management System, Kinetics Concepts Inc, [KCI] an Acelity Company, San Antonio, Texas) on ileostomy-closure surgical wounds would reduce site infections (SSIs) in comparison with conventional closure and dressing. DESIGN: Prospective interventional pilot study. SETTING: La Paz University Hospital, tertiary care academic hospital Madrid, Spain. PATIENTS: The Prevena device was applied 17...
Myosin molecules from smooth muscle and non-muscle cells are known to self-assemble into side-polar filaments in vitro. However, the situ mechanism of filament assembly is not clear question whether there a unique length for myosin still under debate. In this study we measured lengths 16,587 three types using serial electron microscopy (EM). Sheep airway pulmonary arterial as well rabbit carotid were fixed EM ultra-thin (50-60 nm) sections obtained. traced consecutive determine their...
A retrospective-prospective descriptive and comparative study of two sternal closure techniques in a population 621 patients divided into: group A, steel band (n=300) B, conventional technique (n=321), was carried out between January 2005 December 2007 order to describe compare the results both high-risk for dehiscence mediastinitis. Differences groups association with risk factors were obtained using non-parametric tests statistical analysis. No complications or mortality related use bands...
The wall of hollow organs vertebrates is a unique structure able to generate active tension and maintain nearly constant passive stiffness over large volume range. These properties are predominantly attributable the smooth muscle cells that line organ wall. Although known possess plasticity (i.e., ability adapt changes in cell length through structural remodeling contractile apparatus cytoskeleton), detailed basis for largely unknown. Dense bodies, one most prominent structures cells, have...
Introduction: Zinc deficiency is common in children among populations developing areas. alters the immune system and resistance to infections.Objective: To evaluate effect of two zinc compounds prevention acute respiratory infection diarrhea.Materials methods: Randomized triple-blind community trial with 301 between 2-5 years age from six child daycare centers Medellin, Colombia. Children were distributed three groups receiving amino acid chelate, sulfate placebo five days a week for 16...
Contraceptive use in Rwanda tripled since 2005. This study aims to understand the role of coordinated and integrated public family planning service delivery achieving this increase contraceptive Rwanda.This qualitative 2018 included eight focus group discussions with providers 32 in-depth interviews experienced users.Results indicate a well-coordinated system community health workers nurses filling different complementary roles meeting client needs at local level. In addition, integration...
Purpose Legg-Calvé-Perthes disease is an idiopathic avascular necrosis of the femoral head. Although many surgical approaches to treat late presentation this pathology have been proposed, there are few reports about early results double osteotomy procedure (femoral varus combined with Salter innominate osteotomy). The purpose study was describe obtained in patients disease. Methods Cross-sectional evaluation ten intervened osteotomy. There were seven males and three females a mean age 9.2 ±...
Introduction: Iron depleted deposits are the first link in chain of events leading to iron deficiency which is most prevalent nutritional shortage and main cause anemia worldwide. This situation can be prevented through food fortification.Objective: To compare efficacy amino acid chelate with ferrous sulfate as fortifier a dietaryc omplement preschoolers deficiency.Materials methods: study was blinded clinical trial randomized groups. We analyzed 56 (ferritin < 24 ng/ml) that received 13 g...
describir las características epidemiológicas y los resultados del tratamiento quirúrgico temprano de pacientes con diagnóstico endocarditis infecciosa intervenidos en el Departamento Cirugía Cardiovascular la Clínica Medellín, Colombia. estudio observacional, descriptivo, retrospectivo, todos tratados mediante cirugía entre enero 2003 2010. se incluyeron total 54 pacientes, 37 (68,5%) ellos género masculino. La mediana edad fue 57,5 años (9 - 76 años). El 77,7% tenía algún factor riesgo...
Arthroscopic rotator cuff repairs are associated with moderate-to-severe pain. Opioids not the first line for postsurgical pain control due to their potential misuse and side effects. Transdermal buprenorphine represents an alternative multimodal postoperative control.
PurposeOsteoarthritis of the trapeziometacarpal (TMC) thumb joint is one most common and debilitating degenerative osteoarthritic conditions hand. Two available surgical options include arthrodesis versus arthroplasty; latter uses complete or partial trapeziectomy. Suspension with a suture button avoids use tendon grafts favors early rehabilitation. Our purpose was to evaluate long-term results suspension arthroplasty using technique in Colombian cohort.MethodsThis retrospective study...
Case: We describe the case of a 3-year-old boy who presented with limited flexion in left knee. High-resolution magnetic resonance imaging allowed visualization fibrotic muscle band anatomic position fifth component quadriceps muscle, which was confirmed by surgical findings. After resection, patient achieved full recovery range motion Conclusion: To our knowledge, this is first reported previously described accessory that caused knee child.