A5029516101- Pulmonary Hypertension Research and Treatments
- Cardiovascular Function and Risk Factors
- Cardiovascular Issues in Pregnancy
- Vascular Anomalies and Treatments
- Heart Failure Treatment and Management
- Ultrasound in Clinical Applications
- Cardiac Valve Diseases and Treatments
- Hemodynamic Monitoring and Therapy
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Venous Thromboembolism Diagnosis and Management
- Chemical Thermodynamics and Molecular Structure
- Obstructive Sleep Apnea Research
- Cardiac tumors and thrombi
- Ferrocene Chemistry and Applications
- Digital Mental Health Interventions
- Cardiac Arrhythmias and Treatments
- Thermal and Kinetic Analysis
- Family and Patient Care in Intensive Care Units
- Pneumocystis jirovecii pneumonia detection and treatment
- Electron Spin Resonance Studies
- Mobile Health and mHealth Applications
- Cardiovascular Health and Disease Prevention
- Atrial Fibrillation Management and Outcomes
- Systemic Sclerosis and Related Diseases
- Lung Cancer Diagnosis and Treatment
Fondazione Toscana Gabriele Monasterio
2016-2025
Regione Toscana
2013-2024
Azienda Sanitaria Universitaria Integrata di Trieste
2021
National Research Council
2017
Istituto di Fisiologia Clinica
2017
ASL Roma
2013
Abstract Background The diagnosis of pulmonary hypertension (PH) relies on measuring artery pressures at right heart catheterization (RHC). Echocardiographic tricuspid regurgitation velocity (TRV) is a screening tool to define PH probability. While latest guidelines reduced RHC threshold for diagnosis, TRV thresholds were not. We aimed update probability according the novel criteria. Methods Patients undergoing suspected prospectively enrolled. A retrospective cohort was used external...
Abstract Aims This study aimed to evaluate a novel echocardiographic algorithm for quantitative estimation of pulmonary artery wedge pressure (PAWP) and vascular resistance (PVR) in patients with heart failure hypertension (PH) scheduled right catheterization (RHC). Methods results In this monocentric study, 795 consecutive (427 men; age 68.4 ± 12.1 years) undergoing echocardiography RHC were evaluated. Multiple regression analysis was performed identify predictors PAWP PVR measured by the...
Abstract Aim To obtain real-world evidence about the features and risk stratification of pulmonary arterial hypertension (PAH) with a left heart disease (LHD) phenotype (PAH-LHD). Methods results By reviewing records consecutive incident PAH patients at 7 tertiary centers from 2001 to 2021, we selected 286 subjects all parameters needed determine death baseline first follow-up COMPERA 2.0 scores. Fifty seven (20%) had PAH-LHD according AMBITION definition. Compared no-LHD ones, they were...
Abstract Aims The use of loop diuretics in pulmonary arterial hypertension (PAH) is less frequent compared with heart failure. clinical and prognostic characteristics PAH patients according to diuretic remain unexplored. In this study, we retrospectively analysed the survival requiring different doses diuretics. Methods results Patients diagnosed between 2001 2022 at seven European centres for management PAH. According median equivalent dose furosemide overall cohort, were divided into two...
Obstructive sleep apneas (OSA) are a breathing disorder characterized by recurrent and hypopneas associated with complete or partial obstruction of the upper airways during sleep, resulting in disturbed architecture, repeated hypoxemia awakenings, daytime sleepiness. OSA syndrome affects up to 34% men 17% women Western countries. Abnormalities airway anatomy (frequently due obesity), muscle tone, neural control main causes. is impaired cognitive function favors onset hypertension, being...
Background An app providing material for education and entertaining is a possible way to support patients healthcare providers in achieving person-centered care. Methods tailored on the Fondazione Toscana Gabriele Monasterio (FTGM), research hospital treating cardiac lung disorders, was created. A pilot evaluation project conducted consecutive hospitalized heart or disorders. Patients were asked complete an assessment questionnaire. Results The FTGM provides information diagnostic...
Abstract Aims Pulmonary hypertension (PH) affects millions of people worldwide. Right heart catheterization (RHC) is the gold standard to correctly classify subtype PH. Biventricular coupling index (BCI) a new echocardiographic defined as ratio between non-invasive right ventricular stroke work (RVSWI) and E/E′ ratio. Due his comprehensive functional characterization physiology, we hypothesized it might identify pre-capillary Methods results BCI was derived in cohort 334 patients from...
Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure >20 mmHg at rest during right heart catheterization. PH prevalence about 1% of the global population. The clinical classification includes five groups: arterial hypertension, associated with left disease, lung obstructions, unclear and/or multifactorial mechanisms. In case suspicion, echocardiography first-line tool to start diagnostic process. Right catheterization gold standard for diagnosis PH, requires great...
Abstract Background Use of higher dose loop diuretics has been associated with worse survival in acute and chronic heart failure. The use type 1 pulmonary hypertension (PAH) is generally less frequent compared to failure required doses may be lower. the clinical prognostic characteristics patients requiring high PAH remain unexplored. Purpose We studied different diuretic their association PAH. Methods Patients a diagnosis according 2015 European guidelines criteria enrolled from 2001 2021...
Abstract Introduction Subclinical left heart disease (LHD) may impact the management of pulmonary arterial hypertension (PAH) [1]. Purpose To evaluate influence a LHD phenotype on PAH risk stratification. Methods We retrospectively reviewed data consecutive patients followed at 7 tertiary centers from 2001 to 2021, and selected those with all parameters available determine death by means COMPERA 2.0 scores, both baseline first reassessment including right catheterization. These subjects were...
In PH the measure of pulmonary function tests (PFT) and arterial blood gases (ABG) are used to identify underlying lung disease. We wondered if there could be a relationship among indices PFT, ABG (paO2, paCO2), gas exchange (A-a DO2, a-ADCO2, VDphy/VT) haemodynamic variables in population patients. <b>Methods:</b> Sixteen patients with suspicion underwent diffusing capacity (DLCO), ABG, exchange, right heart cath; physiological dead space tidal volume was measured. Mean values their SD were...
Do cardiac patients need psychosocial therapy?/ Echocardiographic assessment of the right heart 15 points) in intervention group vs. control (p<0.05).Pts from displayed a significant decrease anxiety as measured by both questionnaires (all p<0.05) but depression scores remained unchanged.The effects preventive counseling Intervention Control Differences between groups at 12 months Baseline After