A5066503629- Vitamin D Research Studies
- Nutrition and Health in Aging
- Antioxidant Activity and Oxidative Stress
- Exercise and Physiological Responses
- Adipose Tissue and Metabolism
- Head and Neck Cancer Studies
- Oral health in cancer treatment
- Cancer, Stress, Anesthesia, and Immune Response
- Gut microbiota and health
- Biotin and Related Studies
- Vitamin C and Antioxidants Research
- Regulation of Appetite and Obesity
- Cancer, Lipids, and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Diet and metabolism studies
- Muscle metabolism and nutrition
- Antimicrobial Peptides and Activities
- Adrenal Hormones and Disorders
- Dietary Effects on Health
- Cancer Cells and Metastasis
- Estrogen and related hormone effects
- Skin Protection and Aging
- Nutritional Studies and Diet
- Muscle Physiology and Disorders
- HER2/EGFR in Cancer Research
Centre de Recherche en Nutrition Humaine d'Auvergne
2015-2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2014-2024
Unité de Nutrition Humaine
2015-2024
Université Clermont Auvergne
2010-2022
Clermont Université
2013-2021
Laboratoire de Microbiologie et Génétique Moléculaires
2020
Centre de Recherche en Nutrition Humaine Rhône-Alpes
2013-2017
Cancéropôle Lyon Auvergne-Rhône-Alpes
2011-2015
Institut National de la Recherche Agronomique
2006-2013
Centre Hospitalier Universitaire de Clermont-Ferrand
2010
Background: Immunosenescence contributes to reduced vaccine response in elderly persons, and is worsened by deficiencies nutrients such as Vitamin (Vit-D). The immune system a well-known target of Vit-D, which can both potentiate the innate inhibit adaptive system, so modulate vaccination response. Objective: This randomized placebo-controlled double-blind trial investigated whether Vit-D supplementation deficient persons could improve influenza seroprotection Design: Deficient volunteers...
Abstract Growing evidence indicates that the human gut microbiota interacts with xenobiotics, including persistent organic pollutants and foodborne chemicals. The toxicological relevance of microbiota-pollutant interplay is great concern since chemicals may disrupt functions, a potential impairment host homeostasis. Herein we report within batch fermentation systems impact food contaminants (polycyclic aromatic hydrocarbons, polychlorobiphenyls, brominated flame retardants, dioxins,...
Despite decades of therapeutic trials, effective diagnosis, many drugs available and numerous studies on breast cancer, it remains the deadliest cancer in women. In order to choose most appropriate treatment understand prognosis patients, is divided into different subtypes using a molecular classification. Just as there need discover new therapies, models test them are also required.The EO771 (also named E0771 or EO 771) murine mammary cell line was originally isolated from spontaneous...
As the European population is getting older, there growing need in scientific data on how to achieve healthy and successful aging. A decline immune function with age unanimously supported by many epidemiological clinical observations, a decrease T-cell mediated encompassing large part of this alteration. In EU-funded VITAGE project, effects aging biomarkers status are being studied three countries. According strict inclusion/exclusion criteria, cohort 300 male non-smoking 20–75 years old...
Breast cancer is influenced by factors such as diet, a sedentary lifestyle, obesity, and postmenopausal status, which are all linked to prolonged hormonal inflammatory exposure. Physical activity offers protection against breast modulating hormones, immune responses, oxidative defenses. This study aimed assess how high-fat diet (HFD) affects the effectiveness of physical in preventing managing mammary tumorigenesis. Ovariectomised C57BL/6 mice were provided with an enriched environment...
Overtraining syndrome is a condition resulting from excessive training load associated with inadequate recovery and poor sleep quality, leading to performance decrements fatigue. Here we hypothesized that vitamin D (VitD) deficiency lead factor in the development of overtraining syndrome. To test this hypothesis, two groups 60-week-old C57BL/6 mice followed 16-week eccentric-based by downhill running or without dietary VitD depletion (EX EX-D- groups). Two control were trained uphill at same...
Obesity is associated with oxidative stress, a major factor in carcinogenesis, and high leptin concentration. The aim of this study was to determine the effects on antioxidant response three human mammary epithelial cells each presenting different neoplastic status: healthy (HMEC), oestrogen-receptor positive MCF-7 triple-negative MDA-MB-231 cells. This vitro kinetic characterized cell after 1, 6 24 h presence (10 or 100 ng/ml).The defined terms glutathione content, gene expression catalytic...
Leptin, a pleiotropic adipokine, is known as regulator of food intake, but it also involved in inflammation, immunity, cell proliferation, and survival. Leptin receptor integrated inside cholesterol-rich microdomains called lipid rafts, which, if disrupted or destroyed, could lead to perturbation lytic mechanism. Previous studies reported that leptin induce membrane remodeling. In this context, we studied the effect remodeling activity modulation induced by leptin. Thus, primary mouse...
ABSTRACT Despite decades of therapeutic trials, detection, many drugs available and numerous studies on breast cancer, it remains the most deadly cancer in women. In order to choose appropriate treatment know prognosis patients, is divided into different subtypes using a molecular classification. Thus, need discover new effective therapy necessary, requiring have models test them. The EO771 (also named E0771 or EO 771) murine mammary cell line originally isolated from spontaneous tumor...