A5079380128- Dementia and Cognitive Impairment Research
- RNA modifications and cancer
- Geriatric Care and Nursing Homes
- Cancer-related molecular mechanisms research
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- Family Caregiving in Mental Illness
- Nutrition and Health in Aging
- Palliative Care and End-of-Life Issues
- Intergenerational Family Dynamics and Caregiving
- Gene expression and cancer classification
- Health and Wellbeing Research
- Cancer survivorship and care
- Health disparities and outcomes
- Workplace Health and Well-being
- Nursing education and management
- Frailty in Older Adults
- Molecular Biology Techniques and Applications
- Health, psychology, and well-being
- Healthcare Decision-Making and Restraints
- Lung Cancer Treatments and Mutations
- Genomics and Phylogenetic Studies
- Dysphagia Assessment and Management
- Retirement, Disability, and Employment
- Circular RNAs in diseases
Jilin University
2015-2025
Hebei University of Technology
2012-2025
Huadong Hospital
2021-2025
Fudan University
2021-2025
Jilin Medical University
2017-2024
University of Central Florida
2019-2024
St. Jude Children's Research Hospital
2024
Taian City Central Hospital
2024
Affiliated Zhongshan Hospital of Dalian University
2021-2023
Henan University of Traditional Chinese Medicine
2023
Long non-coding RNA nuclear-enriched abundant transcript 1 (NEAT1) plays an important role in the pathogenesis and development of several types cancer. However, functional mechanism NEAT1 hepatocellular carcinoma (HCC) remains unclear. microRNA (miR)-129-5p expression HCC tissues cell lines was quantified by means quantitative PCR. The effects inhibition or upregulation were analyzed terms viability apoptosis. Biological software used to predict binding sites miR-129-5p. miR-129-5p target...
Abstract The open‐circuit voltage ( V OC ) and fill factor (FF) of perovskite solar cells (PSCs) are detrimentally weakened by carrier loss at the perovskite/charge transport layers (CTLs) interfaces. Herein, a dual interfacial modification strategy via placing Nb 2 CT x nanosheets with tailored optoelectrical properties induced manipulating surface terminal groups both perovskite/CTLs interfaces is employed. Such tactics not only concurrently implement mobility enhancement CTLs interface...
An ethyl acetate (EtOAc) extract isolated from the marine bacterium, Rheinheimera aquimaris QSI02, was found to exhibit anti-quorum sensing (anti-QS) activity. A subsequent bioassay-guided isolation protocol led detection of an active diketopiperazine factor, cyclo(Trp-Ser). Biosensor assay data showed that minimum inhibitory concentration (MIC) cyclo(Trp-Ser) ranged 3.2 mg/ml 6.4 mg/m for several microorganisms, including Escherichia coli, Chromobacterium violaceum CV026, Pseudomonas...
Classified as a complex big data analytics problem, DNA short read alignment serves major sequential bottleneck to massive amounts of generated by next-generation sequencing platforms. With Von-Neumann computing architectures struggling address such computationally-expensive and memory-intensive task today, Processing-in-Memory (PIM) platforms are gaining growing interests. In this paper, an energy-efficient parallel PIM accelerator (AlignS) is proposed execute based on optimized...
Accurate disease phenotype prediction plays an important role in the treatment of heterogeneous diseases like cancer era precision medicine. With advent high throughput technologies, more comprehensive multi-omics data is now available that can effectively link genotype to phenotype. However, interactive relation datasets makes it particularly challenging incorporate different biological layers discover coherent signatures and predict phenotypic outcomes. In this study, we introduce...
Abstract The aim of this study was to investigate the role NEAT1 in hepatocellular carcinoma (HCC), and probe whether participate epithelial‐mesenchymal transition (EMT) metastasis regulated by HIF‐2α. Expression lncRNA initially assessed HCC tissues a series cell lines. correlations between levels HIF‐2α were analyzed through plasmid vector construction. potential underlying mechanisms performed vitro vivo functional assays. NEAT1, significantly increased Then, assays revealed that promotes...
In this work, we present GraphS architecture, which transforms current Spin Orbit Torque Magnetic Random Access Memory (SOT-MRAM) to massively parallel computational units capable of accelerating graph processing applications. can be leveraged greatly reduce energy consumption dealing with underlying adjacency matrix computations, eliminating unnecessary off-chip accesses and providing ultra-high internal bandwidth. The device-to-architecture co-simulation for three social network data-sets...
[Purpose] To investigate the effect of Tai Chi on cognitive and physical function in elderly. [Subjects Methods] A randomized trial design was used. total 150 subjects were enrolled divided into control groups. Subjects group participated for 6 months, other non-athletic activities. [Results] There no differences between groups one leg standing time with eyes open, left grip strength, or Frontal Assessment Battery at bedside after 3 months intervention. The Mini-Mental State Examination...
Many national studies have shown that nurses a high turnover rate. The key to maintaining the stability of nursing staff is explore factors affect their intention; however, no research has been performed influencing and mechanisms nurses' intention based on Theory Planned Behaviour.Based Behaviour, examining relationships among resilience, job satisfaction, social support nurses, structural equation model was constructed examine mediating role satisfaction between resilience intention.In...
The frail elderly have an increased risk of frailty because reduced physical activity, cognitive ability and quality life. This study aims to evaluate the effects integrated exercise intervention on attenuation in nursing home residents. was a cluster randomized controlled trial. SETTING AND PARTICIPANTS: 146 people from 8 homes Harbin, China, were randomly assigned into group control after obtaining their informed consent. performed interventions for 12 months, while only continued with...
Abstract In the big data era, images serve as essential carriers of visual information, widely utilized across fields such commerce, healthcare, education, and military. To ensure security digital images, image encryption has been concerned. this paper, we propose an algorithm using a novel two-dimensional (2D) chaotic map, V-shaped scanning matrix multiplication. Firstly, combine two classical seed maps, Logistic map Infinite Collapse Map (ICM) to form 2D hyper-chaotic named 2D-LICM, which...
Aim: The aim of this study was to compare the efficacy and safety fixed-dose combination (FDC) pioglitazone metformin supplemented with dapagliflozin (test group) those basal insulin (control in patients inadequately controlled type 2 diabetes mellitus (T2DM). Methods: This 16-week, prospective, randomized, open-label enrolled aged 18– 75 years glycated hemoglobin (HbA1c) levels between ≥ 8% ≤ 11%. primary endpoint proportion who achieved HbA1c < 7% at week 16 without hypoglycemia or weight...