A5101519117- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Coronary Interventions and Diagnostics
- Advanced X-ray and CT Imaging
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- MRI in cancer diagnosis
- Radiation Dose and Imaging
- Hepatitis C virus research
- Lipoproteins and Cardiovascular Health
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Hypoxia, and Metabolism
- Indoor Air Quality and Microbial Exposure
- Inflammasome and immune disorders
- Cardiac tumors and thrombi
- Pericarditis and Cardiac Tamponade
- Nosocomial Infections in ICU
- Atomic and Subatomic Physics Research
- Microbial Metabolism and Applications
- Venous Thromboembolism Diagnosis and Management
- Brain Metastases and Treatment
- Cancer Research and Treatments
Shanghai Jiao Tong University
2018-2025
Shanghai First People's Hospital
2024-2025
First Hospital of Jilin University
2024
Jilin University
2024
Shanghai Sixth People's Hospital
2018-2023
China Medical University
2007-2021
First Hospital of China Medical University
2013-2015
German Cancer Research Center
2012
DKFZ-ZMBH Alliance
2012
Rutgers New Jersey Medical School
2002-2003
Background Direct intraindividual comparison of dynamic CT myocardial perfusion imaging (MPI) and machine learning (ML)-based fractional flow reserve (FFR) has not been explored for diagnosing hemodynamically significant coronary artery disease. Purpose To investigate the diagnostic performance MPI ML-based FFR functional assessment stenosis. Materials Methods Between January 2, 2017, October 17, 2018, consecutive participants with stable angina were prospectively enrolled. All underwent...
Background: Dynamic computed tomography (CT) myocardial perfusion imaging (MPI) provides quantitative blood flow for the precise assessment of ischemia. However, compared with coronary CT angiography (CCTA), whether this functional modality can reduce invasive without revascularization remains unknown. We aimed to determine clinical outcomes a dynamic CT-MPI+CCTA-guided versus CCTA-guided strategy in patients suspected artery disease. Methods: Consecutive intermediate pretest probability...
To investigate the diagnostic performance of quantified plaque analysis and high-risk characterization by coronary computed tomography angiography (CCTA) for identifying thin-cap fibroatheroma (TCFA).Patients who underwent both CCTA intravascular ultrasound (IVUS) within 4 weeks were retrospectively included. CT-derived quantitative qualitative parameters, including diameter stenosis, minimal lumen area (MLA), low attenuation (LAP) volume napkin-ring sign (NRS), positive remodeling (PR)...
To investigate the prognostic value of computed tomography fractional flow reserve (CT-FFR) in patients with diabetes and to establish a risk stratification model for major adverse cardiac event (MACE).Diabetic intermediate pre-test probability coronary artery disease were prospectively enrolled. All referred angiography followed up at least 2 years. In training cohort comprising 957 patients, two models developed: model1 inclusion clinical conventional imaging parameters, model2...
// Haibo Shao 1 , Jian Zhang 2 Ziping Sun 3 Feng Chen 4 Xu Dai Yaming Li Yicheng Ni 1,2,3,4 and Ke Department of Radiology, The First Hospital China Medical University, Shenyang, Laboratory Translational Medicine, Jiangsu Provincial Academy Traditional Chinese Nanjing, Radiation Institute, Shandong Sciences, Jinan, Imaging & Pathology, Theragnostic Laboratory, University Leuven, Belgium Correspondence to: Xu, email: Ni, Keywords : necrosis, targeted radiotherapy, hypericin, vascular...
To investigate the serial changes of computed tomography (CT) fractional flow reserve (CT-FFR) and fat attenuation index (FAI), explore their relationships with long-term clinical outcomes.Consecutive symptomatic patients an intermediate pretest probability coronary artery disease 1-4 were prospectively enrolled if CT angiography (CCTA) revealed at least 1 lesion 30-70% stenosis on major epicardial arteries. Follow-up CCTA was performed to 1.5-year intervals. All further followed up after...
Evaluation of vascular disrupting treatment (VDT) is generally based on tumor size and enhancement conventional magnetic resonance imaging (MRI) which, unfortunately, may be limited in providing satisfactory information. The purpose the study to evaluate consecutive changes 20 rabbit VX2 liver tumors after VDT by dynamic contrast-enhanced MRI (DCE-MRI) diffusion-weighted (DWI) at a 3.0 T MR unit. Twenty four hours intravenous injection Combretastatin A-4-phosphate (CA4P) mg/kg, DCE-MRI...
The present study aimed to investigate the association between myocardial blood flow (MBF) quantified by dynamic CT perfusion imaging (CT-MPI) and increments in heart rate (HR) after stress patients without obstructive coronary artery disease.We retrospectively included 204 subjects who underwent both CT-MPI angiography (CCTA). Patients with more than minimal stenosis (diameter ≥ 25%), history of infarction/revascularization, cardiomyopathy, microvascular dysfunction were excluded. Global...
To investigate the diagnostic performance of CT fractional flow reserve (CT-FFR) for myocardial bridging-related ischemia using dynamic perfusion imaging (CT-MPI) as a reference standard.Dynamic CT-MPI and coronary angiography (CCTA) data obtained from 498 symptomatic patients were retrospectively reviewed. Seventy-five (mean age ± standard deviation, 62.7 13.2 years; 48 males) who showed bridging in left anterior descending artery without concomitant obstructive stenosis on included. The...
Background Whether statin treatment can improve hemodynamic status of coronary atherosclerotic plaque remains unknown. It is clinical interest to explore the change lesions after treatment. Methods and Results Consecutive patients with intermediate pre-test probability artery disease were prospectively enrolled underwent baseline computed tomography angiography (CCTA) as well follow-up CCTA. The primary end point was determine lesion-specific △computed tomography-derived fractional flow...
This study aimed to explore the diagnostic accuracy of cardiac magnetic resonance tissue tracking (CMR-TT) technology in quantitative evaluation left myocardial infarction for differentiating between acute and chronic infarction.A total 104 human subjects were enrolled this prospective study. Among them, 64 healthy 40 patients with ventricular 7 days 6 months' follow-up CMR studies, including steady-state free precession (SSFP) sequence late gadolinium enhancement MR imaging, enrolled. The...
Myocardial blood flow (MBF), CT fractional reserve (CT-FFR) and high-risk plaque (HRP) features have been revealed to be associated with patients' prognosis. However, direct intra-individual comparison of these CT-derived parameters has not explored yet. The aim this study was investigate the prognostic value MBF, CT-FFR HRP for predicting major adverse cardiac events (MACEs).Consecutive patients chest pain intermediate-to-high pre-test probability coronary artery disease (CAD) were...
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The Value of Low-Dose Dynamic Myocardial Perfusion CT for Accurate Evaluation Microvascular Obstruction in Patients With Acute InfarctionMengmeng Yu1, Xiuyu Chen2, Xu Dai1, Jingwei Pan3, Yining Wang4, Bin Lu5 and Jiayin Zhang1Audio Available | Share Claim CREDIT