A5066957913- Liver Disease Diagnosis and Treatment
- Biomarkers in Disease Mechanisms
- Hormonal Regulation and Hypertension
- Inflammasome and immune disorders
- Apelin-related biomedical research
- Liver Disease and Transplantation
- Dialysis and Renal Disease Management
- Bioactive Compounds and Antitumor Agents
- Adipokines, Inflammation, and Metabolic Diseases
- Parathyroid Disorders and Treatments
- Olfactory and Sensory Function Studies
- Human Health and Disease
- Advanced Glycation End Products research
- Paraoxonase enzyme and polymorphisms
- Pancreatitis Pathology and Treatment
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Attention Deficit Hyperactivity Disorder
- Potato Plant Research
- Acute Myocardial Infarction Research
- Chemotherapy-induced organ toxicity mitigation
- Drug-Induced Hepatotoxicity and Protection
- Sesame and Sesamin Research
- Sulfur Compounds in Biology
- Occupational Health and Performance
- Cardiac Ischemia and Reperfusion
Acıbadem Adana Hospital
2023
Necmettin Erbakan University
2012-2022
Turkish Society of Hematology
2018
Antalya Bilim University
2018
Selçuk University
2012-2014
Konya Food and Agriculture University
2014
University of Colorado Denver
2011
American Physical Therapy Association
2011
Sivas State Hospital
2008-2010
Norsk Hydro (Norway)
2009
Inflammation contributes to the pathogenesis of acute kidney injury (AKI). IL-33 is a proinflammatory cytokine, but its role in AKI unknown. Here we observed increased protein expression full-length following induction with cisplatin. To determine whether promotes injury, administered soluble ST2 (sST2), fusion that neutralizes activity by acting as decoy receptor. Compared cisplatin-induced untreated mice, mice treated sST2 had fewer CD4 T cells infiltrate kidney, lower serum creatinine,...
Psoriasis is a common chronic and recurrent inflammatory skin disease with unknown etiology that has been associated abnormal plasma lipid metabolism oxidative stress. There are controversial results in the previous studies investigating oxidant/antioxidant systems psoriasis.The aim of this work was to evaluate dyslipidemia, stress, total antioxidant capacity serum paraoxonase (PON1) arylesterase (ARE) activities psoriasis, look for correlation between these parameters lesion percentage...
Objectives: Cardiovascular risk is increased in the early stages of chronic kidney disease (CKD) and also found to be ongoing renal transplant (Rtx) patients. As a sign atherosclerosis, carotid intima–media thickness (CIMT) has been widely accepted as strong predictor cardiovascular (CVD) mortality end-stage (ESRD) Ischemia-modified albumin (IMA), pentraxin-3 (PTX-3), neutrophil-to-lymphocyte ratio (NLR) were introduced oxidative stress inflammatory biomarkers ESRD. The role Rtx terms...
To explore the protective effect of progesterone on inflammation and oxidative stress in a rat model sepsis created by cecal ligation puncture (CLP).Rats were randomly divided into 4 groups: Overiectomy group (OVX), sham operated (control), (CLP) progesterone-treated CLP (CLP+ progesterone). The rats CLP+ received intraperitoneal (2 mg/kg). Cardiac blood samples obtained for measurement levels interleukin-6 (IL-6) tumor necrosis factor-α (TNF-α). Tissue samples, including liver, kidney...
Objectives: Acute kidney injury (AKI) is a common complication of cardiac surgery developing in 25–35% cases. Recently, neutrophil gelatinase-associated lipocalin (NGAL) was shown to predict AKI development earlier than serum creatinine. Some studies demonstrated the predictive role post-operative uric acid (SUA) as an early marker AKI. We aimed study and urine NGAL well SUA progression Design methods: This prospective observational patients undergoing surgery. Blood samples for measurement...
Background. Asthma is characterized by inflammation and airway hyperesponsiveness, which results in episodic airflow obstruction. A relationship between insulin resistance (IR) has been previously characterized, asthma known to correlate with increasing IR. Thus, we tested whether patients bronchiale exhibited abnormally low glucose tolerance. The aim of this study was compare the occurrence impaired fasting (IFG) tolerance (IGT), two precursors type 2 diabetes mellitus (DM), paired control...
To assess the prevalence of hepatitis B and C viruses among Turkish patients with type 1 2 diabetes mellitus to determine risk factors affecting in these patient groups.This study included 630 diabetic 314 nondiabetic patients. Serologic testing for anti-hepatitis virus (anti-HCV) HbsAg was done using a third-generation commercial enzyme-linked immunosorbent assay, samples positive anti-HCV were confirmed by polymerase chain reaction assay. Diabetic classified status evaluated according...
Obesity is a major health problem. We investigated the effects of forskolin and rolipram in diet animals which obesity had been induced. used 50 female albino Wistar rats that were assigned randomly into five groups as follows: group 1, control; 2, high fat diet; 3, + forskolin; 4, rolipram; 5, forskolin. The fed for 10 weeks administered during last two weeks. sacrificed blood samples obtained. Serum cAMP, cGMP free fatty acids (FFA) levels measured using ELISA assays. also weight gain week...
Abstract Background Cardiovascular diseases, among which atherosclerotic heart disease, are known to be one of the most important mortality and morbidity causes in patients with rheumatoid arthritis (RA). Ischemia modified albumin (IMA) is a potential marker that can used assess atherosclerosis‐related myocardial ischemia. Another frequently for assessment lesions carotid intima media thickness (CIMT). Aim To evaluate role IMA has on atherosclerosis development its clinical usability RA, by...
Cardiovascular risk is increased in the early stages of chronic kidney disease (CKD) and also found to be ongoing renal transplant (Rtx) patients. As a sign atherosclerosis, carotid intima-media thickness (CIMT) has been widely accepted as strong predictor cardiovascular (CVD) mortality CKD A novel markers, soluble tumor necrosis factor-like weak inducer apoptosis (sTWEAK) neutrophil-to-lymphocyte ratio (NLR) were introduced potential markers inflammatory disorders including CKD. The role...
Objective Ischemia‐modified albumin ( IMA ) is a novel marker for diagnosis of myocardial ischemia and it considered as serum marker. The aim the study was to evaluate salivary levels in patients with acute infarction AMI determine relation between levels. Methods A total 60 40 control subjects who are age sex matched group were included our study. based on WHO classification criteria. All underwent clinical assessment, consisting electrocardiography, cardiac markers. Serum measured at first...
BACKGROUND/AIMS: Atherosclerosis and inflammation are the most important risk factors in pathogenesis of cardiovascular diseases (CVD) patients with end-stage renal disease (ESRD). Pentraxin-3 (PTX-3) was shown to predict atherosclerosis ESRD patients. However, role transplantation (Rtx) terms atherogenesis is still unclear. We aimed investigate relationship between PTX-3, neutrophil-to-lymphocyte ratio (NLR), carotid intima-media thickness (CIMT) Rtx healthy controls. METHODS: This a...
The aim of the study was to determine serum ischemia modified albumin and malondialdehyde levels as markers oxidative stress superoxide dismutase activity a marker antioxidant defense their associations with clinical outcomes in patients fibromyalgia.59 fibromyalgia 38 age gender matched healthy controls were included study. diagnosis based on classification criteria declared by American College Rheumatology 1990. All underwent assessment, consisting evaluation for tender point count, visual...
Vasopressin exerts robust influences on social communication and behavior in humans. Apelin is a relatively novel neuropeptide that could counteract vasopressin's actions has been shown to be closely related with broad range of physiological functions. Abnormalities vasopressin apelin have detected variety psychiatric disorders, but their relation attention-deficit hyperactivity disorder (ADHD) unknown. In the present study, we explored plasma levels apelin-13 children ADHD.Thirty-four ADHD...