- Parkinson's Disease Mechanisms and Treatments
- Central Venous Catheters and Hemodialysis
- Neurotransmitter Receptor Influence on Behavior
- Nerve injury and regeneration
- Neurological disorders and treatments
- Inflammatory Bowel Disease
- Diagnosis and treatment of tuberculosis
- Celiac Disease Research and Management
- Clostridium difficile and Clostridium perfringens research
- Place Attachment and Urban Studies
- Vascular Procedures and Complications
- Latin American Urban Studies
- Vascular anomalies and interventions
- Aortic aneurysm repair treatments
- Bacterial Identification and Susceptibility Testing
- Liver Diseases and Immunity
- Hemodynamic Monitoring and Therapy
- Leptospirosis research and findings
- Bone health and osteoporosis research
- Neuroscience and Neuropharmacology Research
- Chemical synthesis and alkaloids
- Pregnancy and preeclampsia studies
- Hip and Femur Fractures
- Conflict, Peace, and Violence in Colombia
- Peripheral Artery Disease Management
Hospital Clínic de Barcelona
2013-2025
Thomas Jefferson University
2024
Facultad Latinoamericana de Ciencias Sociales
2024
Pontificia Universidad Católica del Ecuador
2021
Instituto Nacional de Enfermedades Respiratorias
2021
Clínica Santa María
2019
Universidad de la República
2018
Rutgers, The State University of New Jersey
2013
The University of Tokyo
2011-2013
Johnson University
2013
Linezolid is an antibiotic with time-dependent activity, and both the percentage of time that plasma concentrations exceed MIC area under concentration-time curve over 24 h in steady state divided by (AUC24/MIC ratio) are associated clinical response. The aim this study was to analyze linezolid trough concentration (C(min)) determine factors a C(min) < 2 mg/liter other clinically relevant thresholds. Characteristics 78 patients receiving 600 mg/12 determination at within first 10 days...
Abstract Background The majority of patients with primary sclerosing cholangitis (PSC) have inflammatory bowel disease (IBD). This association has fostered several pathogenic hypotheses linking mucosal immunity to hepatobiliary inflammation. A putative therapeutic target along this axis centres on gut-derived IL-17 secretor cell subtypes, which are activated by interleukin (IL)23. Notably, emergent forms IBD treatment host anti-IL23 agents, however safety and efficacy data in PSC is limited....
La obesidad es un serio problema de salud pública a nivel mundial, siendo resultado múltiples factores, pero que principalmente consecuencia consumo excedente energía través los alimentos y por otro lado gasto energético reducido falta actividad física. El objetivo del presente estudio determinar el índice central marcadores antropométricos su relación con hábitos reportados universitarios. Metodología. Estudio observacional, analítico transversal. muestra no probabilística invitación se...
The prenatal development of the normal diaphysis human long bone was studied through postmortem radiographs in 60 stillborns and 86 newborns 20-41 weeks gestational age. Quantitative parameters were determined for tibia, femur, humerus. In all three bones, significant positive correlations found between diaphyseal diameter, medullary cortical thickness, area, age, body weight, height, length. No differences any observed males females. diameter grew more than femur these two latter growth...
Nossa, Juan M. MDa; Márquez, Diego Rodriguez, Sebastian MDb; Muñoz, Manuel Alzate, Ricardo Ospina, Jorge MDc; Vallejo, Carlos MDc Author Information
En las últimas décadas, el desarrollo económico de Quito ha venido acompañado con un deterioro en su calidad del aire, principalmente por aumento progresivo flota vehicular. Ante ello, la autoridad ambiental zona registra concentraciones que superan normas nacionales e internacionales aire los parámetros PM10, PM2.5 y O3. este escenario, implementación infraestructura verde urbana (IVU) emerge como una alternativa para mejoramiento microambientes, sin embargo, sus costos limitan aplicación....
Abstract COVID-19 outbreak has caused over 3 million deaths worldwide. Understanding disease pathology and the factors that drive severe fatal clinical outcomes is of special relevance. Studying role respiratory microbiota in particularly important since it’s known interacts with host immune system, contributing to chronic acute diseases. Here, we characterized tract patients mild, severe, or COVID-19, compared healthy controls non-COVID-19-pneumonia. We comparatively studied microbial...
The patient, a forty-two-year-old drug addict, sat frozen and mute, looking more like mannequin than man…" So begins Dr. J. William Langston his wonderful story called 'The Case of the Tainted Heroin' [1].Dr. also added an illustrative subtitle: 'a Trail Tragedies Leads to New Theory Parkinson's Disease'.What author recounts in this scientific article (and posteriorly book Frozen Addicts' [2]) is number heroin abusers who presented at different emergency rooms with indistinguishable symptoms...
Abstract Background Magnetic resonance enterography (MRE) provides an accurate evaluation of transmural lesions in Crohn’s Disease (CD). However, MRE findings associated with poor long-term outcomes CD are not yet defined. Identification such parameters would help defining therapeutic goals. AIMS to identify predictors clinical based on performed 46 weeks after biological treatment initiation patients CD. Methods single-center, prospective, longitudinal study conducted from 2010 2019....
Ibogaine is a psychedelic alkaloid which has been subject of intense scientific research due to its reported ability attenuate drug-seeking behavior. Recent work suggested that ibogaine effects on alcohol self-administration in rats was related the release Glial Cell Derived Neurotrophic Factor (GDNF) Ventral Tegmental Area (VTA), mesencephalic region hosts soma dopamine neurons. It well known neurotrophic factors (NFs) mediate neuroadaptations induced mesocorticolimbic dopaminergic system...