- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal-Organic Frameworks: Synthesis and Applications
- Magnetism in coordination complexes
- Nanoplatforms for cancer theranostics
- Crystallography and molecular interactions
- Metal complexes synthesis and properties
- Advanced Nanomaterials in Catalysis
- Synthesis and Characterization of Heterocyclic Compounds
- Crystal structures of chemical compounds
- Lanthanide and Transition Metal Complexes
- Nanoparticle-Based Drug Delivery
- Synthesis of Tetrazole Derivatives
- Supercapacitor Materials and Fabrication
- Organometallic Compounds Synthesis and Characterization
- Dendrimers and Hyperbranched Polymers
- Immune cells in cancer
Northwest A&F University
2021-2025
Zhejiang University of Science and Technology
2024
Xinjiang University
2017-2019
Metal–organic frameworks (MOFs) hold tremendous potential in cancer therapy due to their remarkable structural and functional adaptability, enabling them serve as nanocarriers for biopharmaceuticals nanoreactors organizing cascade bioreactions. Nevertheless, MOFs are predominantly utilized biologically inactive carriers most cases. Developing nanoscale prodrug suitable biomedical applications remains a huge challenge. In this study, we have designed novel nano-MOFs (nMOFs, named DCCMH) using...
A novel core-shell metal organic framework (MOF), Cu-MOF@SMON/DOX-HA, was fabricated using 3-amino-1,2,4-triazole (3-AT) and organosilicon for combined chemo-chemodynamic therapy with high drug-loading capacity, pH/GSH dual-responsiveness, good biocompatibility. The Cu-MOF@SMON/DOX-HA could not only generate reactive oxygen species, but also effectively consume glutathione (GSH) to induce cell ferroptosis. This work involves the modification of on surface MOFs, which possess performance in...
Six new metal-organic coordination polymers (CPs) [Ni(L)(2,5-TDC)(H2O)] n (1), [Ni(L)(1,3-BDC)(H2O)] (2), [Ni(L)(1,4-BDC)(H2O)] (3), [Mn(L)(2,5-TDC)(H2O)] (4), [Mn(L)(2,6-PYDC)(H2O)] (5) and [Mn(L)(1,4-NDC)] (6) were achieved by reactions of the corresponding metal salt with mixed organic ligands (L = 3,6-bis(benzimidazol-1-yl)pyridazine, 2,5-H2TDC thiophene-2,5-dicarboxylic acid, 1,3-H2BDC isophthalic 1,4-H2BDC terephthalic 2,6-H2PYDC pyridine-2,6-dicarboxylic 1,4-H2NDC...
<title>Abstract</title> Metal-organic frameworks (MOFs) hold tremendous potential in cancer therapy due to their remarkable structural and functional adaptability, enabling them serve as nanocarriers for biopharmaceuticals nanoreactors organizing cascade bioreactions. Nevertheless, MOFs are predominantly utilized biologically inactive carriers most cases. Developing nanoscale prodrug suitable biomedical applications remains a huge challenge. In this study, we have designed novel nano-MOFs...