Zhaofei Xia

ORCID: 0000-0002-7567-1007
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Animal Nutrition and Physiology
  • Gut microbiota and health
  • Probiotics and Fermented Foods
  • Antibiotic Resistance in Bacteria
  • Antimicrobial Peptides and Activities
  • Bacteriophages and microbial interactions
  • Bacterial Identification and Susceptibility Testing
  • Respiratory viral infections research
  • Parasitic Infections and Diagnostics
  • Influenza Virus Research Studies
  • Antibiotics Pharmacokinetics and Efficacy
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Meat and Animal Product Quality
  • Mast cells and histamine
  • Antimicrobial Resistance in Staphylococcus
  • Vector-borne infectious diseases
  • Genomics and Phylogenetic Studies
  • Diet and metabolism studies
  • Pharmacological Effects of Natural Compounds
  • Adipose Tissue and Metabolism
  • Dietary Effects on Health
  • Microbial infections and disease research
  • Drug-Induced Hepatotoxicity and Protection
  • Virology and Viral Diseases
  • Herbal Medicine Research Studies

China Agricultural University
2016-2025

Ministry of Agriculture and Rural Affairs
2023-2025

The effects of Enterococcus faecium on growth, intestinal barrier function, and immune response in Escherichia coli O78-challenged broiler chickens were investigated. Three hundred eight 1-day-old Ross male randomly assigned into three treatment groups: negative control (C), E. O78-infected positive (EP), with 200 mg/kg dietary supplementation (EF). significantly increased the body weight day 10 (P < 0.05) 15. Furthermore, these birds had a greater average daily gain compared other groups...

10.1007/s12602-018-9434-7 article EN cc-by Probiotics and Antimicrobial Proteins 2018-06-11

We investigated antimicrobial resistance trends and characteristics of ESBL-producing Escherichia coli isolates from pets whether this correlates with antibiotic usage in the clinic. Clinical samples containing E. diseased cats dogs were screened for sensitivity associated genotypic features. identified 127 1886 (n = 1565) 321) majority urinary tract infections 108, 85%). High rates observed β-lactams fluoroquinolones to > 3 classes (MDR) increased 67% 2012 75% 2017 (P < 0.0001). This was...

10.3389/fmicb.2019.02852 article EN cc-by Frontiers in Microbiology 2019-12-10

High stocking density (STD) could affect duck welfare and production. The objective of our study was to investigate whether dietary tryptophan (TRP) supplementation alleviate the detrimental effects high STD on ducks. White Pekin ducks at 4 6 wk age were raised 11 birds/m(2) fed diets containing 0.18, 0.48, 0.78, or 1.08% TRP for 21 d. Growth performance, concentrations metabolites in blood hypothalamus, antioxidative activities serum tissue, meat quality, uric acid, urea nitrogen measured....

10.3382/ps/pev155 article EN cc-by-nc-nd Poultry Science 2015-06-19

The aim of this study was to investigate the effects Clostridium butyricum (C. butyricum) on performance, serum lipid metabolism, muscle morphology, meat quality, and fatty acid profiles Peking ducks. A total 1,500 ducks were randomly divided into five groups with replicates fed a non-antibiotic basal diet (Control) or supplemented either 200, 400, 600 mg/kg C. (2.0 × 109 CFU/g) 150 mg aureomycin/kg for 42 d. Compared control group, supplementation increased average daily weight gain but...

10.3382/ps/pey162 article EN cc-by-nc-nd Poultry Science 2018-05-14

Abstract Heat stress (HS) and secondary restricted blood flow to the intestines cause dysfunction of intestinal epithelial barrier. Tight junctions (TJs) are essential maintain integrity. l -Arginine has beneficial effects on gut functions. However, underlying mechanisms remain largely unknown. This study tested hypothesis that -arginine regulates TJ network by activating AMP-activated protein kinase (AMPK) signaling, which in turn improves barrier functions under HS. IEC-6 cells rat small...

10.1007/s11033-019-05090-1 article EN cc-by Molecular Biology Reports 2019-10-01

Abstract China Antimicrobial Resistance Surveillance Network for Pets (CARPet) was established in 2021 to monitor the resistance profiles of clinical bacterial pathogens from companion animals. From 2018 2021, we recovered and tested 4,541 isolates dogs cats across 25 Chinese provinces, with Escherichia coli (18.5%) Staphylococcus pseudintermedius (17.8%) being most predominant species. The Enterobacterales were highly susceptible tigecycline, meropenem, colistin, amikacin (70.3%–100.0%),...

10.1186/s44280-023-00008-w article EN cc-by One Health Advances 2023-03-30

Subcutaneous fat deposition is an important index with which to evaluate meat-producing ducks, and affects their meat quality feed conversion rate. Studying the differentially expressed genes in subcutaneous will help comprehensively understand potential mechanisms regulating ducks. In this study, 72 Nankou 1 Pekin Ducks Jingdian (half male half female) at 42 days of age were selected for slaughter performance transcriptome analysis. The results showed that breast-muscle yield ducks was...

10.3390/ani14020268 article EN cc-by Animals 2024-01-15

This work is aimed to elucidate the prevalence and characteristics of antimicrobial resistance, virulence, molecular typing in Klebsiella pneumoniae from clinical companion animals Beijing, China. In total, 105 K. (2.0%) isolates were recovered 5359 samples (dogs, n = 3356; cats, 2003). All tested exhibited high resistance amoxicillin-clavulanate (74.3%). Moreover, rates dog (2.1%) significantly higher than cat (0.9%); however, rate multidrug-resistance (MDR) was 57.1% MDR cats dogs....

10.3390/pathogens10030271 article EN cc-by Pathogens 2021-02-27

Enterococcus spp., while naturally occurring as commensal bacteria in the gastrointestinal tract of animals and humans, have emerged significant opportunistic pathogens healthcare settings. A comprehensive surveillance study revealed enterococci 14.39% clinical samples from dogs cats across China during 2018-2021. Multidrug-resistant enterococcal infections showed correlation with urinary catheterization extended hospitalization periods. Notably, pet-derived faecalis isolates demonstrated...

10.46234/ccdcw2025.017 article EN Deleted Journal 2025-01-01

Bacterial skin infections are common in dogs and often secondary to underlying conditions like allergies or ectoparasite infestations. Untreated primary causes can lead recurrent an increased risk of antimicrobial resistance, including methicillin-resistant Staphylococcus pseudintermedius (MRSP), posing a substantial clinical challenge. Here, we analyzed 896 canine bacterial infection samples collected from the China Agricultural University Veterinary Teaching Hospital between 2018 2022....

10.3390/pathogens14040309 article EN cc-by Pathogens 2025-03-24

The mechanism of hemolysis induced by onion poisoning in dogs was studied. Six adult, clinically normal Pekingese were fed cooked onions at 30 g/kg body weight/day for 2 days. Blood samples collected on days 1, 3, 5, 8, 12, 18 and 24 after administration, urine the day bleeding. Red blood cell counts, hemoglobin hematocrit decreased from significantly so 5 ( P &lt; 0.01), contrary to results white counts. So plasma bilirubin levels urobilinogen increased 3 0.01) 4 respectively. Heinz counts...

10.1111/j.1365-2885.2007.00930.x article EN Journal of Veterinary Pharmacology and Therapeutics 2008-01-08

Klebsiella pneumoniae complex is an increasingly important bacterial pathogen that capable of causing severe organs and life-threatening disease. This study aimed to investigate the multidrug resistance, phylogroups, molecular characterization, hypervirulence-associated determinants complex, which were isolated from clinical diseased dogs cats. A total 35 K. (2.3%; 95% confidence interval, 1.6-3.2) isolates identified 1,500 samples, all collected randomly veterinary hospitals in 12 regions...

10.3389/fvets.2022.816415 article EN cc-by Frontiers in Veterinary Science 2022-03-10

As an emerging feed additive extracted from the traditional herb milk thistle, silybin has few applications and studies in Peking ducks. The aim of this study was to explore practical significance silymarin application ducks provide more theoretical support for livestock poultry production. A total 156 1-day-old healthy were randomly divided into four groups supplemented with 0 mg/kg (control group), 400 (S400), 800 (S800) 1,600 (S1600) diets at day 14, investigate effects on growth, serum...

10.3389/fvets.2023.1325115 article EN cc-by Frontiers in Veterinary Science 2024-01-03

Abstract Heat stress (HS) and the associated restricted blood flow to intestine have been proven destroy intestinal integrity. Considering beneficial properties of L‐arginine on gut function, we investigated protective effects under HS conditions. In vivo, serum cortisol level rectal temperature increased in response HS. Under HS, damage showed obvious morphological changes. Furthermore, decreased mRNA protein expression levels Nurr1 , ZO‐1 occludin claudin‐6 E‐cadherin NF‐κB IL‐1β cleaved...

10.1111/jpn.13246 article EN Journal of Animal Physiology and Animal Nutrition 2019-11-11

Increased attention is being paid to breast muscle yield and meat quality in the duck breeding industry. Our previous report has demonstrated that dietary Clostridium butyricum (C. butyricum) can improve of Pekin ducks. However, potential biological processes molecular mechanisms are modulated by C. ducks remain unknown. Supplementation with increased growth performance yield. Therefore, we utilized de novo assembly methods analyze RNA-Seq transcriptome profiles explore differentially...

10.1186/s12864-018-5261-1 article EN cc-by BMC Genomics 2018-11-28

Lactobacillus plantarum (LP) contributes to the intestinal health, whereas study about effects of LP on Pekin ducks is lacking. This aimed investigate growth performance and health ducks. A total 180 one-day-old birds were randomly allotted 3 treatments, fed with a basal diet (Control) or supplemented 400 (LP1) 800 (LP2) mg/kg (5 × 109 CFU/g). The animal trial lasted for 42 d. Results showed that LP1 LP2 treatments improved (feed conversion) during period 1 At end 21 d, decreased serum...

10.1016/j.psj.2022.101844 article EN cc-by-nc-nd Poultry Science 2022-03-11
Coming Soon ...