- Cancer survivorship and care
- Chemotherapy-induced cardiotoxicity and mitigation
- Ginkgo biloba and Cashew Applications
- Cancer-related cognitive impairment studies
- Cancer Cells and Metastasis
- Ginseng Biological Effects and Applications
- Cardiovascular and exercise physiology
- Prostate Cancer Treatment and Research
- Blood disorders and treatments
- Glioma Diagnosis and Treatment
- Pharmacological Effects of Natural Compounds
- Intensive Care Unit Cognitive Disorders
- Xenotransplantation and immune response
- Electrolyte and hormonal disorders
- Microfluidic and Bio-sensing Technologies
- Immune Response and Inflammation
- Cardiac Health and Mental Health
- Exercise and Physiological Responses
- Neuroscience and Neuropharmacology Research
- Hormonal Regulation and Hypertension
- Prostate Cancer Diagnosis and Treatment
- Pregnancy and preeclampsia studies
- Pneumocystis jirovecii pneumonia detection and treatment
- S100 Proteins and Annexins
Greater Poland Cancer Center
2015-2024
Cardiotoxicity is known as a severe clinical problem in oncological practice that reduces the options for cancer therapy. Physical exercise recognized well-established protective measure many heart and diseases. In our study, we hypothesized supervised moderate-intensity training would prevent failure its consequences induced by trastuzumab The aim of this study was to examine effect physical on ventricular remodeling, serum cardiac markers, performance women with human epidermal growth...
Measurement of serum prostate specific antigen (PSA) concentrations remains one the leading methods for diagnosing cancer. We developed and evaluated an immunoglobulin Y (IgY)-based ELISA to measure total PSA (tPSA) in human that could be used as alternative commercially available vitro diagnostic assays rely on mouse monoclonal IgG.A sandwich based anti-PSA IgY antibody was developed. ability detect free complexed at same molar ratio. The assay optimized, its analytical performance verified...
Summary Introduction: Despite widespread use of Panax ginseng and Ginkgo biloba, the data on safety as well herb-drug interactions are very limited. Therefore, we postulate that P. G. biloba may modulate activity content cytochrome P450 isozymes involved in biotransformation diverse xenobiotic substances. Objective: The aim our study was to determine influence herbal remedies expression level CYP enzymes transcriptional factors. Methods: Male Wistar rats were given standardized (30 mg/kg...
Exercise has been shown to improve quality of life (QoL) and even treatment outcomes in cancer patients. However, the evidence support benefits exercise patients with high-grade glioma (HGG) is limited. Therefore, we performed a randomized clinical trial (RCT) examine effect augmented-reality-based rehabilitation exercises on physical functional fitness, cognitive function, fatigue, mood, QoL, selected blood parameters, brain derived neurotrophic factor (BDNF), S100 protein HGG.Adult HGG...
Trastuzumab is indicated in the adjuvant setting for early and intermediate stages of breast cancer (BC) positive epidermal growth factor receptor 2 (HER2). Although HER2 BC patients tends to disrupt pro-oxidant inflammatory signaling, influence trastuzumab modulating this process remains unknown. Due absence any chemotherapeutic or chemoprophylactic agents trastuzumab-induced side effects, study investigated potential role regular physical exercise antioxidant defenses, oxidative stress,...
Radiotherapy (RT) plays a key role in brain tumours but can negatively impact functional outcomes and quality of life. The aim this study was to analyse anti-neural onconeural autoantibodies markers blood–brain barrier (BBB) disruption patients with primary cancer undergoing RT. Materials methods. A prospective conducted on 45 tumour scheduled for intensity-modulated radiotherapy. Assessments were performed at baseline, post-RT, three months. We measured serum levels BBB biomarkers...
Summary Introduction: Plants are a rich source of healing substances. Cancer is leading cause death worldwide while breast cancer the most common among women. Circulating tumour cells (CTCs) potential founder for metastasis. Therefore, their assessment may be used monitoring treatment as well detecting metastatis. Hence, it suggested that number CTCs valuable biomarker during therapy. Objective: The purpose this study was to detect in and validate method CTC count using CytoTrack CT11...