- Pregnancy and preeclampsia studies
- Medicinal Plant Extracts Effects
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Medicinal Plants and Neuroprotection
- Medicinal Plants and Bioactive Compounds
- Reproductive System and Pregnancy
- Pharmacological Effects of Natural Compounds
- Birth, Development, and Health
- Cholinesterase and Neurodegenerative Diseases
- Ginkgo biloba and Cashew Applications
- Cannabis and Cannabinoid Research
- Herbal Medicine Research Studies
- Bee Products Chemical Analysis
- Curcumin's Biomedical Applications
- Natural Antidiabetic Agents Studies
- Phytochemical and Pharmacological Studies
- Plant tissue culture and regeneration
- Pineapple and bromelain studies
- Trace Elements in Health
- Traditional Chinese Medicine Analysis
- Plant Toxicity and Pharmacological Properties
- Drug Transport and Resistance Mechanisms
- Blood Coagulation and Thrombosis Mechanisms
Institute of Natural Fibres and Medicinal Plants
2016-2025
Poznan University of Medical Sciences
2010-2018
Pomeranian Medical University
2016
Among natural substances widespread in fruits, vegetables, spices, and medicinal plants, flavonoids organic acids belong to the promising groups of bioactive compounds with strong antioxidant anti-inflammatory properties. The aim present work was evaluate antibacterial activity 13 common (flavones, flavonols, flavanones) 6 (aliphatic aromatic acids). minimal inhibitory concentrations (MICs) selected plant were determined by micro-dilution method using clinical strains four species pathogenic...
Curcumin, a principal bioactive substance of turmeric (Curcuma longa L.), is reported as strong antioxidant, anti-inflammatory, antibacterial, antifungal, and antiviral agent. However, its antimicrobial properties require further detailed investigations into clinical multidrug-resistant (MDR) isolates. In this work, we tested curcumin's efficacy against over 100 strains pathogens belonging to 19 species. This activity was determined by the broth microdilution method calculating minimum...
Candidiasis is a common oral and vaginal infection. Some papers have presented that the essential oils of Lamiaceae plants can antifungal activity. This study aimed to investigate activity 7 family with known phytochemical compositions against Candida fungi.Forty-four strains belonging six species were tested: C. albicans, glabrata, guilliermondii, krusei, parapsilosis, tropicalis. During this investigation, following methods used: determination minimal inhibitory concentrations (MICs),...
Passiflora caerulea L., P. alata Curtis and incarnata L. (synonym for edulis Sims), are the most popular representatives of genus in South America. In recent years, a growing attention is paid to biological activity phytochemical profiles crude extracts from various species worldwide. The aim this study was evaluate compare anti-leukemic dry leaves three greenhouse Poland two human acute lymphoblastic leukemia cell lines: CCRF-CEM its multidrug resistant variant. Two systems liquid...
Twenty-nine flavonoid glycosides were identified in the aqueous extract (PC) of <italic>Petroselinum crispum</italic> var. <italic>crispum</italic> leaves and apiin, major compound, was isolated thereof.
The inappropriate use of antimicrobials, along with environmental conditions, can lead to the emergence resistant microorganisms. phytopharmaceuticals and herbal medicines has a positive impact represents promising alternative. Psidium guajava extracts have been widely reported antimicrobial potential; however, studies reporting their activity against bacterial strains are scarce. Because emerging resistance, aim this study was analyze capacity aqueous extract guava leaves wild-type strains....
Melissa officinalis (MO, English: lemon balm, Lamiaceae), one of the oldest and still most popular aromatic medicinal plants, is used in phytomedicine for prevention treatment nervous disturbances. The aim our study was to assess effect subchronic (28-fold) administration a 50% ethanol extract MO leaves (200 mg/kg, p.o.) compared with rosmarinic acid (RA, 10 huperzine A (HU, 0.5 on behavioral cognitive responses scopolamine-induced rats. results were linked acetylcholinesterase (AChE),...
Background: Foodborne infections affect approximately 600 million people annually. Simultaneously, many plants contain substances like organic acids, which have antimicrobial activity. The aim of this study was to examine the effects 21 naturally occurring in plants, on four foodborne bacteria (Staphylococcus aureus, Listeria monocytogenes, Escherichia coli, and Salmonella enterica Typhimurium) two fungi (Geotrichum candidum Penicillium candidum). Methods: minimal inhibitory concentrations...
Pelargonium graveolens is a plant of significant importance in natural medicine, as well cosmetics and aromatherapy. This species rich secondary metabolites, including geraniol, citronellol, linalool, which gives it antibacterial, anti-inflammatory sedative properties. Currently, there an increase demand for P. plants, especially the oil produced from them. Clonal propagation techniques vitro culture new biotechnological methods can facilitate large-scale production genetically identical...
Glioblastoma (GBM) is one of the most invasive central nervous system tumors, with rising global incidence. Therapy resistance and poor prognosis highlight urgent need for new anticancer drugs. Plant alkaloids, a largely unexplored yet promising class compounds, have previously contributed to oncology treatments. While past reviews provided selective insights, this review aims collectively compare data from last decade on (1) plant alkaloid-based drugs, (2) alkaloid transport across...
Micropropagation of Passiflora species and its hybrids may play an important role in the production healthy disease-free plants which can be a source medicinal herbal products, nutritional fruits ornamental flowers. The rapid multiplication elite to obtain pharmacognostic material, containing valuable flavonoid C-glycosides, is possible by usingcontrolled vitro conditions, constituents medium interactions plant growth regulators (1-naphtaleneacetic acid, benzyladenine, gibberellin...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Łukasz Mikołajczak P, Kędzia B, Ożarowski M, et al. Evaluation of anti-inflammatory and analgesic activities extracts from herb Chelidonium majus L. Central European Journal Immunology. 2015;40(4):400-410. doi:10.5114/ceji.2015.54607. APA Mikołajczak, P., Kędzia, B., Ożarowski, M., Kujawski, R., Bogacz, A., & Bartkowiak-Wieczorek, J. (2015). Immunology, 40(4), 400-410. https://doi.org/10.5114/ceji.2015.54607...