A5103142015- Chronic Myeloid Leukemia Treatments
- Acute Lymphoblastic Leukemia research
- Chronic Lymphocytic Leukemia Research
- Pharmacological Effects of Natural Compounds
- HIV/AIDS drug development and treatment
- Adipose Tissue and Metabolism
- Acute Myeloid Leukemia Research
- Regulation of Appetite and Obesity
- Pharmacological Effects and Toxicity Studies
- Breastfeeding Practices and Influences
- Neuroscience and Neuropharmacology Research
- Phytochemistry and Biological Activities
- Biochemical Analysis and Sensing Techniques
- Biochemical effects in animals
- Pharmaceutical studies and practices
- Phytoestrogen effects and research
- Lipoproteins and Cardiovascular Health
- Natural product bioactivities and synthesis
- Hepatitis C virus research
- Cardiovascular and exercise physiology
- Antibiotics Pharmacokinetics and Efficacy
- Medicinal Plants and Bioactive Compounds
- Pain Mechanisms and Treatments
- Balance, Gait, and Falls Prevention
- Muscle metabolism and nutrition
Poznan University of Medical Sciences
2012-2024
University School of Physical Education in Kraków
2014-2022
State School of Higher Professional Education in Płock
2022
Instytut Matki i Dziecka
2001-2020
Mother and Child Foundation
2017-2020
Shantou University
2018
Hungarian University of Sports Science
2001
Boston Children's Hospital
1997
Melissa officinalis (MO, English: lemon balm, Lamiaceae), one of the oldest and still most popular aromatic medicinal plants, is used in phytomedicine for prevention treatment nervous disturbances. The aim our study was to assess effect subchronic (28-fold) administration a 50% ethanol extract MO leaves (200 mg/kg, p.o.) compared with rosmarinic acid (RA, 10 huperzine A (HU, 0.5 on behavioral cognitive responses scopolamine-induced rats. results were linked acetylcholinesterase (AChE),...
To test the hypotheses that short-term bed-rest (BR) deconditioning influences metabolic, cardiorespiratory, and neurohormonal responses to exercise these effects depend on subjects' training status, 12 sedentary men 10 endurance- strength-trained athletes were submitted 3-day BR. Before after BR they performed incremental until volitional exhaustion. Respiratory gas exchange heart rate (HR) recorded continuously, stroke volume (SV) was measured at submaximal loads. Blood taken for lactate...
The conjugate 8 was obtained as a result of condensation 3-hydroxyiminooleanolic acid morfolide (7) and aspirin in dioxane. Analgesic effect OAO-ASA (8) for the range doses 0.3 – 300.0 mg/kg (p.o.) performed mice using hot plate test. Anti-inflammatory activity assessed on carrageenan-induced paw edema rats same doses. did not significantly change locomotor mice, therefore sedative properties compound should be excluded. proved simple, proportional, dose-dependent analgesic action expressed...
Eryngium planum L. (EP) is as a rare medicinal plant with lot of potentials pharmaceutical crops. The aim our study was to assess the effect subchronic (28-fold) administration 70% ethanol extract EP roots (200 mg/kg, p.o.) on behavioral and cognitive responses in Wistar rats linked acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), beta-secretase (BACE-1) mRNA levels AChE BuChE activities hippocampus frontal cortex. On last day experiment, 30 min after dose or Huperzine A (HU),...
[Purpose] To assess the effect of 12-weeks Nordic walking training on gait parameters and some elements postural control. [Subjects Methods] Sixty-seven women aged 65 to 74 years were enrolled in this study. The subjects divided into a Walking group (12 weeks training, 3 times week for 75 minutes) control group. In both study groups, set functional tests conducted at beginning end study: Forward Reach Test (FRT) Upward (URT) stabilometric platform, analysis treadmill. [Results] NW showed...
The aim of this work was to analyze postural stability girls having progressive form idiopathic scoliosis and undergoing specific period the adolescent growth spurt. Twenty-seven girls, aged 13.4 ± 1.2 years, presenting structural scoliosis, thoracic or thoracolumbar pattern, radiological Cobb angle 41.7 17.4° (study group) 37 healthy (control were included. groups sex, age, height, weight, BMI matched. Postural examination performed using two stabilometric platforms with visual control...
Morphine is co-administered with adjuvant drugs to treat pain, nausea, vomiting, dyspnoea and delirium in cancer patients.To investigate analgesic effects of morphine when drugs.Two-month-old male Wistar rats received single doses alone (0.45 0.9 mg/kg) or midazolam (0.3 mg/kg), haloperidol (0.15 0.45 levomepromazine (0.35 metoclopramide (1.0 hyoscine butylbromide (1.7 as subcutaneous injections. Analgesia was measured by the tail-flick test after 15, 30, 45, 60, 90 min drug administration....
The aim of this study was to assess the activity extracts from Platycodon grandiflorum A. DC (PG) in a model chronic bronchitis rats. research carried out on three water extracts: E1 – roots field cultivated PG; E2 biotransformed E3 callus PG. differed saponins and inulin levels—the highest measured lowest E1. Identification secondary metabolites performed using two complementary LC-MS systems. Chronic induced by sodium metabisulfite (a source SO2). Animals were treated with for weeks (100...
Abstract 10-Alkylthiocolchicines have been obtained and characterized by spectroscopic methods their biological activities as: cytotoxic, anti-inflammatory analgesic tested. Cytotoxic activity against SKOV-3 ovarian cell line for 10-alkylthiocolchicine analogues was reported tested compounds showed to be more active than commonly used doxorubicin. Some of C-10 alkylthiolated colchicines found exhibit cytotoxicity at levels comparable that the natural product—colchicine....
The extent of knee extensor and flexor weakness after disruption ligaments affects a rehabilitation output functional recovery may give prognostic information on possible risk development osteoarthritis.The hypothesis tested was whether patients with multiple-ligament tear would have larger abnormalities in strength the extensors flexors than an isolated-ligament rupture.Cross-sectional study, level III.Outpatient orthopedic clinic.3 groups recreationally active men: noninjured control (CON,...
Background: Tramadol is often coadministered subcutaneously with adjuvants to treat pain, nausea/vomiting, dyspnea and delirium in cancer patients. The aim of the study was investigate analgesia tramadol rats. Materials Methods: Male rats (Wistar race) received a single dose separately (0.45 mg/kg) or haloperidol mg/kg), midazolam (0.3 levomepromazine (0.35 metoclopramide (1.0 hyoscine butylbromide (1.7 ketamine as subcutaneous injection. Analgesia measured by tail flick test after 15, 30,...
Summary Introduction : In recent years, the search for potential neuroprotective properties of salidroside and its ability to influence activity nervous system become subject intense studies many research groups. None these studies, however, include an attempt determine effect on course alcohol tolerance in vivo . Objective The aim this study was investigate inhibit development rats, determining whether action may occur a dose-dependent manner, reducing both metabolic central without...
The study was carried out on alcohol-preferring male Wistar rats. following drugs were repeatedly (28×) administered: acamprosate (500 mg/kg, p.o.), naltrexone (0.1 i.p), and Pueraria lobata (kudzu) root extract (KU) p.o.) its isoflavones: daidzin (40 puerarin (150 p.o.). Their effects a voluntary alcohol intake assessed. KU also given for 9 days in an experiment tolerance development. Finally, total active ghrelin levels peripheral blood serum measured by ELISA method. Acamprosate,...
Rheumatoid arthritis is a chronic inflammatory disease leading to disability, reduced quality of life, and severe depressive symptoms. Theoretical models research emphasize the importance cognitive factors such as illness-related beliefs appraisals in process adapting life with disease. Objectives: The aim this study was analyze role age, duration, level acceptance rheumatoid determine responsible for short-term (one week) changes without use interventions. We also assessed differences...