A5033587750- Advanced Radiotherapy Techniques
- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Research Studies
- Lung Cancer Treatments and Mutations
- Brain Metastases and Treatment
- Colorectal Cancer Screening and Detection
- Neuroendocrine Tumor Research Advances
- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Cancer Immunotherapy and Biomarkers
- MRI in cancer diagnosis
- Liver Disease Diagnosis and Treatment
- Dermatologic Treatments and Research
- Colorectal Cancer Treatments and Studies
- Pancreatic and Hepatic Oncology Research
- Liver Disease and Transplantation
- Lung Cancer Diagnosis and Treatment
- Advances in Oncology and Radiotherapy
- Effects of Radiation Exposure
- Medical Imaging Techniques and Applications
- Renal cell carcinoma treatment
- Cancer, Hypoxia, and Metabolism
- Cholangiocarcinoma and Gallbladder Cancer Studies
Allegheny Health Network
2017-2025
Allegheny General Hospital
2016-2024
Bogomolets National Medical University
2022
Ministry of Health
2022
West Virginia University
2018-2021
New York Proton Center
2021
Unfallkrankenhaus Berlin
2019
Cancer Institute (WIA)
2018
Innsbruck Medical University
2014
Objective: The relationship between microsatellite instability (MSI) and response to neoadjuvant chemoradiation in rectal cancer is not well understood. Background: We utilized the National Cancer Database (NCDB) investigate association MSI pathologic complete (pCR) this patient population. Methods: analyzed 5086 patients 2010 2015 with locally advanced who were tested for treated definitively followed by surgery. Primary comparison groups 4450 MSI-negative(−) 636 MSI-positive(+) patients....
To evaluate the control, survival, and hepatic function for Child Pugh (CP)-A patients after Stereotactic body radiotherapy (SBRT) in hepatocellular carcinoma (HCC).From 2009 to 2016, 40 with Barcelona Liver Clinic (BCLC) stages 0-B HCC CP-A cirrhosis completed liver SBRT. The mean prescription dose was 45 Gy (40 50 4-5 fractions). Local relapse, defined as recurrence within planning target volume assessed intravenous multiphase contrast computed tomography or magnetic resonance imaging...
We report on the feasibility and outcomes of liver stereotactic body radiation therapy (SBRT) for hepatocellular carcinoma (HCC) with single-photon emission computed tomography (SPECT) functional treatment planning in patients Child-Pugh (CP) B/C cirrhosis.
A 1.5T MRI combined with a linear accelerator (Unity®, Elekta; Stockholm, Sweden) is device that shows promise in MRI-guided stereotactic body radiation treatment (SBRT). Previous studies utilized the manufacturer’s pre-set sequences (i.e., T2 Weighted (T2W)), which limited visualization of pancreatic and intra-abdominal tumors organs at risk (OAR). Here, T1 (T1W) sequence was to improve OAR for online adapted-to-position (ATP) adapted-to-shape (ATS) during SBRT. Twenty-six patients, 19 7...
616 Background: The relationship between microsatellite instability (MSI) and response to neoadjuvant chemoradiation in rectal cancer is not well understood. We therefore utilized the national database (NCDB) investigate association MSI pathologic complete (pCR) this patient population. Methods: analyzed 5,086 patients 2010-2015 with locally advanced who were tested for treated definitively followed by surgery. Primary comparison groups 4,450 MSI-negative(-) 636 MSI-positive(+) patients....
Repeat computed tomography (CT) simulation is problematic because of additional expense clinic resources, patient inconvenience, radiation exposure, and treatment delay. We investigated the factors clinical impact unplanned CT resimulations in our network.We used billing records 18,170 patients treated at 5 clinics. A total 213 were resimulated before their first treatment. The disease site, location, use 4-dimensional (4DCT), contrast, image fusion, cause for resimulation recorded. Odds...
Intraoperative planning with transrectal ultrasound (US) is used for accurate seed placement and optimal dosimetry in prostate brachytherapy. However, magnetic resonance imaging (MRI) has shown superiority delineation of anatomy. Accordingly, MRI/US fusion may be useful intraoperative planning. We analyzed to compare differences volume that derived from the postoperative computed tomography (CT).Twenty patients underwent preoperative MRI, which was fused intraoperatively US during 125I or...
Purpose/objectivesInduction chemotherapy followed by chemoradiation and surgical resection in rectal cancer, known as total neoadjuvant therapy (TNT), is associated with improved pathologic complete response (pCR) rates.The National Cancer Database was utilized to identify factors pCR survival following treatment TNT compared standard (nCRT). Materials/methodsThe queried from 2004 2015 for patients locally advanced, nonmetastatic cancer.We identified 16,299 receiving radiation definitive...
Surgery remains the standard of care in rectal cancer. Select patients will not undergo surgery for reasons such as medical inoperability or a watch-and-wait approach and instead are managed with definitive chemoradiation.We used National Cancer Database to identify overall survival predictors thereof nonoperative management cancer.This was retrospective review.This study deidentified data from Database.We queried national cancer database 2004 2014 stage 1 3 adenocarcinoma treated only...