Juan Manuel Domínguez

ORCID: 0000-0002-7627-4767
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About
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Research Areas
  • Veterinary Pharmacology and Anesthesia
  • Anesthesia and Sedative Agents
  • Anesthesia and Pain Management
  • Periodontal Regeneration and Treatments
  • Osteoarthritis Treatment and Mechanisms
  • Liver Disease and Transplantation
  • Hemodynamic Monitoring and Therapy
  • Antibiotics Pharmacokinetics and Efficacy
  • Tendon Structure and Treatment
  • Knee injuries and reconstruction techniques
  • Organ Transplantation Techniques and Outcomes
  • Shoulder Injury and Treatment
  • Pharmacological Effects and Assays
  • Sepsis Diagnosis and Treatment
  • Monoclonal and Polyclonal Antibodies Research
  • Airway Management and Intubation Techniques
  • Anesthesia and Neurotoxicity Research
  • Pediatric Pain Management Techniques
  • Veterinary Equine Medical Research
  • Energy, Environment, and Transportation Policies
  • HER2/EGFR in Cancer Research
  • Respiratory Support and Mechanisms
  • Coccidia and coccidiosis research
  • Cardiac Arrest and Resuscitation
  • Cocoa and Sweet Potato Agronomy

University of Córdoba
2016-2025

Université Laval
2022-2024

Escuela Superior Politecnica del Litoral
2009-2023

Estudios Clínicos Latinoamérica
2023

Instituto Cardiovascular de Rosario
2022

Cordoba University
2008-2022

Bellvitge University Hospital
1995-2017

Universidad de Málaga
2012

Centro Médico Sanitas Málaga
2012

CIUDAD
2009

Urbanization may influence physical activity (PA) levels, although little evidence is available for low- and middle- income countries where urbanization occurring fastest. We evaluated associations between total PA, as well work-, leisure-, home-, transport-specific 138,206 adults living in 698 communities across 22 within the Prospective Urban Rural Epidemiology (PURE) study. The 1-week long-form International PA Questionnaire was administered at baseline (2003-2015). used satellite-derived...

10.1038/s41598-022-26406-5 article EN cc-by Scientific Reports 2023-01-06

Purpose: The aim of this study was to compare the efficacy and safety a single intra-articular injection adipose mesenchymal stem cells (aMSCs) versus plasma rich in growth factors (PRGF) as treatment for reducing symptoms dogs with hip osteoarthritis (OA). Methods: This randomized, multicenter, blinded, parallel group. Thirty-nine symptomatic OA were assigned one two groups, receive aMSCs or PRGF. primary outcome measures pain function subscales, including radiologic assessment, functional...

10.3390/ijms150813437 article EN cc-by International Journal of Molecular Sciences 2014-07-31

Transcatheter Arterial Chemoembolization in Patients with Hepatocellular Carcinoma on the Waiting List for Orthotopic Liver TransplantationEsther Alba1, Carlos Valls1, Juan Dominguez1, Laura Martinez1, Elena Escalante1, Lladó2 and Teresa Serrano3Audio Available | Share

10.2214/ajr.07.2972 article EN American Journal of Roentgenology 2008-04-22

Background: The use of plasma rich in growth factors (PRGF) has been proposed to improve the healing Achilles tendon injuries, but there is debate about effectiveness this therapy. objective present study was evaluate histological effects PRGF, which a type leukocyte-poor platelet-rich plasma, on healing. Methods: tendons twenty-eight sheep were divided surgically. animals randomly into four groups seven each. repaired two received an infiltration PRGF intraoperatively and every week for...

10.2106/jbjs.k.01659 article EN Journal of Bone and Joint Surgery 2013-02-06

Microglia participate in the immune response upon central nervous system (CNS) infections. However, role of these cells during herpes simplex encephalitis (HSE) has not been fully characterized. We sought to identify different microglia/microglia-like and describe potential mechanisms signaling pathways involved HSE.The transcriptional CD11b+ cells, including was investigated using single-cell RNA sequencing (scRNA-seq) on isolated from ventral posterolateral nucleus (VPL)-enriched thalamic...

10.1186/s12974-022-02437-7 article EN cc-by Journal of Neuroinflammation 2022-04-06

Subjective pain assessment scales have been widely used for assessing lameness in response to pain, but the accuracy of these has questioned. To assess scale accuracy, 10 lame, presa Canario dogs with osteoarthritis (OA) associated bilateral hip dysplasia were first treated mesenchymal stem cells. Then, potential improvement was analyzed using two (Bioarth and visual analog scale). These data compared similar collected a force platform same animals during period 6 months after treatment.The...

10.1186/s12917-016-0852-z article EN cc-by BMC Veterinary Research 2016-10-07

Abstract Purpose Articular cartilage is vulnerable to multiple types of damage and it has limited reparative regenerative capacities due its absence vascularity. Although a large number therapeutic strategies exist treat chondral defects, they have some limitations, such as fibrocartilage formation. Therefore, the goal present study was evaluate chondrogenic properties an autologous-made matrix particulated platelet-rich plasma (PACI + PRP) implantation for treatment full-thickness defects...

10.1007/s00167-022-07295-7 article EN cc-by Knee Surgery Sports Traumatology Arthroscopy 2023-01-04

The objective of this study was to evaluate dexmedetomidine as a premedicant in dogs prior propofol–desflurane anaesthesia, and compare it with medetomidine. Six healthy were anaesthetized. Each dog received intravenously (i.v.) five preanaesthetic protocols: D1 (dexmedetomidine, 1 μ g/kg, i.v.), D2 2 M1 (medetomidine, M2 or M4 4 i.v.). Anaesthesia induced propofol (2.3–3.3 mg/kg) maintained desflurane. following variables studied: heart rate (HR), mean arterial pressure, systolic diastolic...

10.1111/j.1365-2885.2006.00732.x article EN Journal of Veterinary Pharmacology and Therapeutics 2006-04-27

Ten New Zealand White rabbits were used in a crossover experimental study: 200 µg/kg medetomidine and 1 (M1) or 2 mg/kg (M2) morphine administered intramuscularly. After preoxygenation, anaesthesia was induced with alfaxalone at 10 intravenously. The trachea intubated 60 per cent oxygen provided. Heart respiratory rates (HR RR), direct arterial pressures (APs), pH (pHa), PaO , PaCO SaO taken baseline, after premedication every minutes during the 90 following induction. times to return ear...

10.1136/vr.101293 article EN Veterinary Record 2014-01-01

Abstract Efforts to improve cacao value chains often assume that production of fine and flavor varieties will raise smallholder incomes. Undertaking postharvest practices fermentation drying is another exercise assumed increase value‐added capture by producers. This study employs household data from 340 farms in 15 villages coastal Ecuador during 2018 empirically assess these assumptions. Contrary the common belief international development community, we find has no association with price...

10.1002/agr.21730 article EN Agribusiness 2022-01-18

A prospective, randomised, blinded controlled study was performed to determine the anaesthetic and cardiorespiratory effects of a constant‐rate infusion (CRI) alfaxalone in 12 sheep anaesthetised with desflurane, undergoing experimental orthopaedic surgery. Sheep were sedated dexmedetomidine (4 μg/kg, intravenously) butorphanol (0.3 mg/kg, intravenously). Anaesthesia induced (1 mg/kg/minute effect, maintained desflurane oxygen 0.07 or saline for 150 minutes (range 150–166 minutes). The...

10.1136/vr.100487 article EN Veterinary Record 2012-07-12

Abstract Objective To (1) evaluate lithium dilution (LiDCO) and transpulmonary thermodilution (PiCCO TD ) in relation to traditional (PAC‐TD) for determining cardiac output (CO) 3 different hemodynamic states dogs (2) compare the continuous CO values obtained using power analysis (PulseCO) with PiCCO (PiCCOc). Design Prospective randomized study. Setting University research laboratory. Animals Fourteen healthy Beagles. Interventions was measured PAC‐TD, LiDCO, induced random order defined on...

10.1111/vec.12219 article EN Journal of Veterinary Emergency and Critical Care 2014-08-20

Autonomic nervous system (ANS) activity can modify cardiovascular parameters in response to nociceptive stimuli or drugs anesthetized animals. The aim of this study was determine if a surgical stimulus and morphine, ketamine, dobutamine administration would ANS observed as change the mean parasympathetic tone (PTAm) horses. In 20 horses, heart rate (HR), arterial pressure (MAP), PTAm were monitored before 1, 3, 5 min after incision, 10 morphine (0.2 mg/kg IV). If nystagmus spontaneous...

10.3390/ani12081038 article EN cc-by Animals 2022-04-15
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