A5021184126- Acute Ischemic Stroke Management
- Metabolomics and Mass Spectrometry Studies
- Neurological Disease Mechanisms and Treatments
- Lipoproteins and Cardiovascular Health
- Lipid metabolism and disorders
- Cerebrovascular and Carotid Artery Diseases
- Retinal Imaging and Analysis
- Extracellular vesicles in disease
- Cardiovascular and Diving-Related Complications
- IgG4-Related and Inflammatory Diseases
- Neuroendocrine Tumor Research Advances
- Retinal Diseases and Treatments
- Thyroid Disorders and Treatments
- Bone health and osteoporosis research
- Stroke Rehabilitation and Recovery
- Traditional Chinese Medicine Studies
- Genetic Associations and Epidemiology
- Brain Metastases and Treatment
- S100 Proteins and Annexins
- Circular RNAs in diseases
- Retinal and Optic Conditions
- MicroRNA in disease regulation
- Cerebrovascular and genetic disorders
- Diet and metabolism studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
University of Oklahoma Health Sciences Center
2020-2023
Duke University
2023
Apple (United States)
2023
Neurology, Inc
2020
Oklahoma City University
2020
Abstract Background Hypertriglyceridemia has emerged as a critical coronary artery disease (CAD) risk factor. Rare loss-of-function (LoF) variants in apolipoprotein C-III have been reported to reduce triglycerides (TG) and are cardioprotective American Indians Europeans. However, there is lack of data other Europeans non-Europeans. Also, whether genetically increased plasma TG due ApoC-III causally associated with CAD still unclear inconsistent. The objectives this study were verify the role...
Abstract Background Acute Ischemic Stroke (AIS), a major cause of disability, was previously associated with multiple metabolomic changes, but many findings were contradictory. Case-control and longitudinal study designs could have played role in that. To clarify we performed simultaneous comparison ischemic stroke metabolome acute, chronic stages controls. Methods Through the nuclear magnetic resonance (NMR) platform, evaluated 271 serum metabolites from cohort 297 AIS patients acute 159 We...
Abstract Background Thyroid hormones are of fundamental importance for brain function. While low triiodothyronine levels during acute ischemic stroke (AIS) associated with worse clinical outcomes, dynamics thyroid function after AIS remains unknown. Thus, we longitudinally evaluated and related them to severity. Methods We prospectively traced stimulating hormone (TSH), free (fT3), thyroxin (fT4) from the hyper-acute (within 24 h) (3–5 days) chronic (3–6 months) stages using a mixed...
To report a rare cause of CADASIL with point mutation in exon 5 NOTCH 3 gene causing non-cysteine change and its implication.
Background: Despite recent advances in treatment, early diagnosis and prognosis of acute ischemic stroke (AIS) suffers from significant limitations. Growing number mostly case-control studies have determined that noncoding, micro-ribonucleic acid (miRNAs) play a role the pathophysiologic processes related to cerebral ischemia post-stroke recovery. This pilot project is longitudinal study, which investigates difference miRNA regulation vs. chronic stage stroke. Hypothesis: Expression some...
Thursday, April 30April 14, 2020Free AccessIgG4 Related Disease Presenting As a Cerebral Mass With Leptomeningeal Enhancement (349)Gina Perez-Giraldo, Sarah Durica, Juliane Chainakul, Ahmad Al-Awwad, and Nidhiben AnadaniAuthors Info & AffiliationsApril 2020 issue94 (15_supplement)https://doi.org/10.1212/WNL.94.15_supplement.349 Letters to the Editor