A5032860845- Reproductive Physiology in Livestock
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Genetic and phenotypic traits in livestock
- Reproductive System and Pregnancy
- Growth Hormone and Insulin-like Growth Factors
- Effects of Environmental Stressors on Livestock
- Milk Quality and Mastitis in Dairy Cows
- Ruminant Nutrition and Digestive Physiology
- Sperm and Testicular Function
- Aquaculture disease management and microbiota
- SARS-CoV-2 and COVID-19 Research
- Birth, Development, and Health
- Probiotics and Fermented Foods
- Estrogen and related hormone effects
- Ovarian cancer diagnosis and treatment
- Asthma and respiratory diseases
- Heat shock proteins research
- Pregnancy-related medical research
- Invertebrate Immune Response Mechanisms
- Animal health and immunology
- Ginseng Biological Effects and Applications
- Skin and Cellular Biology Research
- Neonatal Respiratory Health Research
- Antimicrobial Peptides and Activities
National University of the Littoral
2016-2025
Consejo Nacional de Investigaciones Científicas y Técnicas
2016-2025
Centro Científico Tecnológico - Santa Fe
2015-2024
Complexo Hospitalario Universitario A Coruña
2023
Instituto de Física del Litoral
2013-2022
Centro Científico Tecnológico - Tucumán
2014-2022
Centro Científico Tecnológico - San Juan
2009-2020
Triangle
2017
National Academies of Sciences, Engineering, and Medicine
2010
Universidad Nacional de La Plata
2006
Steroid hormones play an important role in reproduction and the receptors through which they signal change a developmental time, follicle stage, cell-specific manner. Disruption steroid receptor expression affects formation differentiation. In this study, using prenatal testosterone (T) dihydrotestosterone (DHT)-treated female sheep as model systems, we tested hypothesis that androgen excess disrupts ontogeny of ovarian protein expression. Pregnant Suffolk ewes were injected twice weekly...
Prenatal testosterone (T) excess increases ovarian follicular recruitment, persistence, insulin resistance, and compensatory hyperinsulinemia. Considering the importance of in physiology, this study, using prenatal T- dihydrotestosterone (DHT, a nonaromatizable androgen)-treated female sheep, we tested hypothesis that androgen alters intraovarian signaling cascade metabolic mediators have an impact on signaling. Changes receptor (INSRB), substrate 1 (IRS1), mammalian target rapamycin (MTOR),...
Abstract In the context of continuous emergence SARS-CoV-2 variants concern (VOCs), one strategy to prevent severe outcomes COVID-19 is developing safe and effective broad-spectrum vaccines. Here, we present preclinical studies a RBD vaccine derived from Gamma variant adjuvanted with Alum. The Gamma-adapted more immunogenic than Ancestral in terms inducing broader neutralizing antibodies. presents B-cell restricted epitopes induces higher proportion specific-B cells plasmablasts version....
Cystic ovarian disease (COD), characterized by the presence of persistent follicles, is a major cause subfertility in dairy cows. This study aimed to evaluate expression receptors and enzymes involved ketone body metabolism, cholesterol regulation, steroidogenesis within follicular structures at different stages persistence. The was conducted model persistence induced prolonged progesterone administration cows, cows diagnosed with spontaneous COD. protein key components, including HMG-CoA...
Abstract Background Cystic ovarian disease is an important cause of infertility that affects bovine, ovine, caprine and porcine species even human beings. Alterations in the micro-environment females with follicular cysts could alter normal processes proliferation programmed cell death cells. Thus, our objective was to evaluate apoptosis cystic follicles rats order investigate follicle formation persistence. Methods We compared number situ apoptotic cells by TUNEL assay, expression active...
Contents To describe the epidemiology of cystic ovarian disease ( COD ), to find possible risk factors associated with incidence cysts and analyse impact on reproductive performance dairy cows, databases from 22 herds main region in Argentina were retrospectively evaluated throughout a 3‐year period (2009–2011). A total 248 cases over 9156 parturitions recorded, resulting cumulative rate 2.7%. Cystic density was lower during first 100 days post‐partum DPP ) than later stages lactation....
Prenatal testosterone (T) excess leads to reproductive dysfunctions in sheep, which include increased ovarian follicular recruitment and persistence. To test the hypothesis that disruptions T sheep stem from changes developmental ontogeny of proliferation apoptotic factors, pregnant Suffolk were injected twice weekly with propionate or dihydrotestosterone (DHT; a nonaromatizable androgen) Days 30 90 gestation. Changes expression proliferating cell nuclear antigen (PCNA), BCL2, BAX, activated...
Abstract Yerba Mate ( Ilex paraguariensis St. Hill. Aquifoliaceae ) is a native South American tree and has large amount of bioactive compounds. Colorectal cancer (CRC) one the so‐called westernized diseases third most common in both men women. Efficient strategies for treatment CRC are extensively being explored including dietary intervention. The objective our research was to evaluate effects extract on cell proliferation, invasive capacity tumor cells, angiogenesis. For this, vitro vivo...
The purpose of this study was to determine by immunohistochemistry the expression estrogen and progesterone receptors in ovarian follicular structures from cows with cystic disease (COD) compare these normal structures. Secondary, tertiary, atretic, follicles were evaluated. cysts animals COD presented a significantly higher receptor α all layers than secondary, atretic both groups ( P < .05). intensity β granulosa cell layer stronger tertiary secondary .05) growing Theca cells scarcely...
The objective of the present study was to characterise expression and tissue distribution steroid receptors (oestrogen receptor-α –β (ERα, ERβ), androgen receptor (AR) progesterone (PR)) steroidogenic enzymes (P450 aromatase (P450arom), 3β-hydroxysteroid dehydrogenase (3β-HSD) acute regulatory protein (StAR)) in letrozole-induced polycystic ovaries rats. Changes serum hormone levels, whole by western blot analysis localisation immunohistochemistry were determined female rats treated with...