- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Malaria Research and Control
- Mosquito-borne diseases and control
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- COVID-19 and healthcare impacts
- Health and Medical Education
- COVID-19 epidemiological studies
- Child Abuse and Trauma
- Angiogenesis and VEGF in Cancer
- Pharmaceutical Practices and Patient Outcomes
- Data-Driven Disease Surveillance
- Prostate Cancer Treatment and Research
- Lysosomal Storage Disorders Research
- Autoimmune and Inflammatory Disorders Research
- Glycogen Storage Diseases and Myoclonus
- Community Health and Development
- Public Health and Social Inequalities
- Genetic factors in colorectal cancer
- Patient Safety and Medication Errors
- Long-Term Effects of COVID-19
- SARS-CoV-2 detection and testing
- Heavy Metal Exposure and Toxicity
Mexican Social Security Institute
2011-2024
Universidad Autónoma de Nayarit
2021-2023
Cultura
2021-2023
PURPOSE: Hereditary Breast and Ovarian Cancer (HBOC) syndrome is responsible for approximately 5-10% of all diagnosed breast ovarian cancers. cancer the most common malignancy leading cause cancer-related mortality among women in Latin America (LA). The main objective this study was to develop a comprehensive understanding genomic epidemiology HBOC throughout establishment American consortium HBOC-LACAM, consisting specialists from 5 countries LA description results first phase study....
The COVID-19 pandemic has had a devastating impact on global health, necessitating urgent and effective strategies to mitigate its consequences. Vaccination programs have been implemented worldwide combat virus transmission reduce the disease burden. This study aimed investigate relationship between vaccination coverage all-cause excess mortality in 178 nations during first two years of pandemic. Multiple regression analysis, after adjusting for life expectancy at birth, confirmed...
In May 2023, the global health emergency status of COVID-19 concluded, marking onset an endemic era. This study assessed survival rates among PCR-confirmed adult inpatients during this phase and determined contributing factors. Employing a analysis approach, investigation utilized nationwide Mexican cohort encompassing 152 inpatients. Survival were computed using Kaplan–Meier method, proportional Cox model identified mortality risk remained above 65% on day 14 after admission. Vaccination...
To measure the frequency of drug allergies in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), register causal drug, type, severity reaction.Direct interview chart review RA SLE were conducted. We registered demographic data, allergies, how causality was assessed, type allergic reaction. include as only those cases which result exposure re-exposure known or a physician evaluating original event established link suspected drug. Differences between groups...
The burden of influenza in Mexico has been high. We aimed to characterize its epidemiological patterns before and during the coronavirus disease 2019 (COVID-19) pandemic. A retrospective cohort study was conducted 5652 PCR-confirmed cases (October 2019–April 2022) were analyzed. highest incidence (144 per million) observed December rapidly decreased right start pandemic (February 2020). No documented 2020–2021 season, infections reemerged at a low level (8 2021. case-fatality rates around 5%...
Background: Influenza remains a common cause of morbidity and mortality worldwide, viral subtype-related differences in disease outcomes have been documented.Objective: To characterize the survival experience adult inpatients with influenza virus-associated pneumonia by subtype during five consecutive flu seasons.Method: We performed retrospective cohort study; data from 4,678 adults were analyzed using Kaplan-Meier method. A multivariate Cox proportional hazard regression model was...
To compare, in a real-world scenario, the protective effect of vaccination and previous laboratory-confirmed symptomatic infection on risk COVID-19 pneumonia.A retrospective study was conducted 46,998 adults with were enrolled. Risk ratios (RRs) 95% confidence intervals (CIs) used to evaluate evaluated exposures pneumonia.In multiple analysis after adjusting by reinfection status, vaccinated participants at reduced developing pneumonia (RR = 0.974, CI 0.965-0.983). The association having had...
The global health emergency caused by COVID-19 concluded in May 2023, marking the beginning of an endemic phase. This study aimed to evaluate association between vaccination status and other patient characteristics risk severe disease during this new period. A nationwide cohort was conducted Mexico, where we analyzed data from 646 adults who had received positive confirmation through PCR testing August 2023. overall symptoms sample 5.3%. average time elapsed last vaccine shot symptom onset...
Dengue fever remains a significant global health concern, imposing substantial burden on public systems worldwide. Recent studies have suggested that climate change, specifically the increase in surface temperatures associated with warming, may impact transmission dynamics of dengue. This study aimed to assess relationship between annual temperature changes from 1961 2019 and dengue 185 countries. The was evaluated for using disability-adjusted life years (DALYs) rate change (ARC) DALY rates...
OBJETIVO: Evaluar la aptitud en los padres sobre el impacto de educar con equidad a menores, para prevenir abuso sexual infantil una estrategia educativa participativa. MATERIAL Y MÉTODOS: Diseño cuasiexperimental. Se incluyó 92 hijos menores preescolar que recibieron intervención promotora participativa por hora durante 20 días. Para evaluar cambio se construyó previamente un cuestionario estructurado enunciados, fue validado expertos educación y sexología infantil. comparar diferencia...
Currently, the specialist doctor has as part of discharge profile search, analysis and discussion information. Reading comprehension is generated after relationship text with reader responsible for building knowledge by relating what been read learned. We set out to evaluate level critical reading competence in family medicine (MF) residents Family Medicine Unit No. 24 (U.M.F. No.24). from Mexican Social Security Institute (IMSS); To whether they have competence, evaluation instrument was...
The transmission of the dengue virus in Mexico has historically been high, and its burden during COVID-19 pandemic is currently not well understood. Our objective was to assess dengue-related disability-adjusted life years (DALYs) between 2020 2022. We conducted a cross-sectional analysis databases resulting from an epidemiological surveillance vector-borne diseases computed DALYs using protocol Global Burden Disease (GBD) study 2019. results showed that there were 218,807 incident cases...
To evaluate the performance of an instrument for predicting chronic chikungunya arthritis (CCA) in adult patients.A diagnostic test study was conducted and data from 217 confirmed cases virus (CHIKV) illness were analyzed. Two arthralgia scales (3-item CCAS-3 4-item CCAS-4) constructed.Modest scale documented at two given cut-off points. A CCAS-4 score ≥3 showed high sensitivity specificity persistence CCA 12 months after acute disease.If replicated other populations, these results could be...
Repeated SARS-CoV-2 infections are plausible and related published data scarce. We aimed to identify factors associated with the risk of recurrent (three episodes) laboratory-confirmed symptomatic infections.A retrospective cohort study was conducted, 1,700 healthcare workers were enrolled. used ratios (RR) 95% confidence intervals (CI) evaluate infections.We identified 14 participants illness episodes. Therefore, incidence rate 8.5 per 10,000 person months. In a multiple-model study,...
Abstract Introduction: Prostate cancer (CaP) encompasses a range of malignant prostate tissue dysplasias that primarily affects men over 50 years, is the second leading cause mortality in males. VEGF expression associated with tumor progression and metastasis patients CaP. The SNP -1154 G/A severity CaP populations Tunisia United Kingdom while -634 G/C alone has been Tunisian population. It unknown whether these polymorphisms could serve as biomarkers Mexican Aim: To associate - 634 western...
We aimed to report the results from Global Burden of Disease Study 2019 related respiratory malignant tumors (tracheal, bronchial, and lung) in Mexico. also evaluated relationship between burden these neoplasms proportion daily smokers total lead emissions 2019. A cross-sectional analysis ecological data was performed. The 152,189 disability-adjusted life-years (DALYs), years life lost (YLL) contributed 99% them. highest DALYs rates (per 100,000) were observed states Sinaloa, Chihuahua, Baja...
Background: Repeated SARS-CoV-2 infections are plausible and related published data scarce. We aimed to identify factors associated with the risk of recurrent (three episodes) laboratory-confirmed symptomatic infections. Methods: A retrospective cohort study was conducted 1,700 healthcare workers were enrolled. used ratios (RR) 95% confidence intervals (CI) evaluate Results: identified 14 participants illness episodes. Therefore, incidence rate 8.5 per 10,000 person-months. In multiple...
Background: The respiratory syncytial virus infection (RSV) spread has been unusually high during 2022 and increasing trends have documented We aimed to assess the survival experience of children hospitalized due bronchiolitis by laboratory-confirmed RSV. Methods: A nationwide retrospective cohort was conducted in Mexico data from 436 aged 5 years younger, with symptoms onset August 2021 November 2022, were analyzed. Survivor functions 95% confidence intervals (CI) computed using...