Abril Bernardette Martínez-Rizo

ORCID: 0000-0002-8381-3730
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About
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Research Areas
  • Glaucoma and retinal disorders
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogenic Bacteria Studies
  • Immune Response and Inflammation
  • Spaceflight effects on biology
  • Liver physiology and pathology
  • Corneal Surgery and Treatments
  • Neonatal Respiratory Health Research
  • TGF-β signaling in diseases
  • Aging, Health, and Disability
  • Essential Oils and Antimicrobial Activity
  • Pressure Ulcer Prevention and Management
  • Genetic factors in colorectal cancer
  • Antibiotic Resistance in Bacteria
  • Alcohol Consumption and Health Effects
  • Research on Leishmaniasis Studies
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Lung Cancer Treatments and Mutations
  • Turtle Biology and Conservation
  • Curcumin's Biomedical Applications
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Wound Healing and Treatments
  • Insect symbiosis and bacterial influences
  • BRCA gene mutations in cancer
  • Bacterial Identification and Susceptibility Testing

Universidad Autónoma de Nayarit
2014-2024

Autonomous University of Yucatán
2024

Universidad de Guadalajara
2008-2011

The Royal Free Hospital
2008

University College London
2008

PURPOSE: Hereditary Breast and Ovarian Cancer (HBOC) syndrome is responsible for approximately 5-10% of all diagnosed breast ovarian cancers. cancer the most common malignancy leading cause cancer-related mortality among women in Latin America (LA). The main objective this study was to develop a comprehensive understanding genomic epidemiology HBOC throughout establishment American consortium HBOC-LACAM, consisting specialists from 5 countries LA description results first phase study....

10.3389/fonc.2019.01429 article EN cc-by Frontiers in Oncology 2019-12-19

Toll-like receptor 4 (TLR4) non-coding polymorphisms are associated to primary open angle glaucoma (POAG), normal tension glaucoma, and pseudoexfoliation glaucoma. This study was performed determine whether single nucleotide (SNPs) in the TLR4 gene contribute POAG a Mexican population.A total of 187 unrelated patients with 109 control subjects were included. Allelic, genotypic, haplotypic diversity assessed for rs11536889, rs1927911, rs12377632, rs2149356 gene. Genotyping target SNPs by 5'...

10.1080/13816810.2016.1227454 article EN Ophthalmic Genetics 2016-11-28

Aim: To evaluate whether a combination of isosorbide dinitrate spray and chitosan gel (10%) topically applied can have additive benefits for management diabetic foot ulcers. Methods: In randomized, placebo-controlled, double-blinded clinical trial, 68 patients were divided into four groups: Group 1: treated with gel; 2: spray; 3: 4: placebo. Results: Histological analyses showed significant regeneration in all groups ( p < 0.001). On the final assessment ulcer, using was found wound...

10.1177/1479164118769528 article EN Diabetes and Vascular Disease Research 2018-04-23

Fifty years ago, researchers discovered a link between ambient temperature and the sex of turtle embryos. More recently, significant progress has been made in understanding influence on freshwater turtles. However, our key genetic factors other groups, such as sea turtles, remains limited. To address this gap, we conducted RNA-seq analyses embryonic tissues from olive ridley during thermosensitive period (stages 21-26) at temperatures known to produce males (26 °C) females (33 °C). Our...

10.1016/j.ydbio.2024.06.018 article EN cc-by-nc Developmental Biology 2024-06-22

Background: Plasmin role in transforming growth factor-β (TGF-β)-responsive gene regulation remains to be elucidated. Also, plasmin action on co-repressor Ski-related novel protein N (SnoN) and differential activation of matrix metalloproteinases (MMPs) are unknown. Thus, the profibrogenic molecule expression, SnoN transcriptional kinetics gelatinase was investigated. Methods: Hepatic stellate cells (HSC) were transduced with adenovirus-mediated human urokinase plasminogen activator...

10.1111/j.1478-3231.2009.02155.x article EN Liver International 2009-11-02

Pseudomonas aeruginosa is a Gram-negative bacillus considered an opportunistic pathogen, usually associated with nosocomial infections in immunocompromised patients. Among the caused, most frequent are urinary tract infections, wound pneumonia, and bacteremia. It has intrinsic acquired resistance to antibiotics, due low permeability of its outer membrane, overexpression efflux pumps, production enzymes that degrade antibiotic. In this study, 61 samples P. collected from General Hospital “Dr....

10.30574/gscbps.2023.24.2.0335 article EN GSC Biological and Pharmaceutical Sciences 2023-08-27

Many models for predicting dengue epidemics use incidence and short-term changes in climate variables, however, studies real-life scenarios correlations of seroprevalence (SP) with long-term variables integration socio-economic factors are scarce. Our objective was to analyse the combined correlation between SP Mexico.We performed a seroepidemiological ecological study on Mexican Pacific coast. Dengue estimated by presence immunoglobulin G antibodies 1278 inhabitants. We implemented multiple...

10.1093/trstmh/traa083 article EN Transactions of the Royal Society of Tropical Medicine and Hygiene 2020-08-17

Chagas disease (ChD) is a parasitosis caused by the protozoan Trypanosoma cruzi (Tc).It endemic to almost all Latin American countries, including southern United States.The acute form of ChD and its actual incidence have rarely been described in Mexico, despite extensive presence favorable niches for transmission.The objective this study was estimate frequency febrile patients at central Pacific coast Mexico.For this, we surveyed with persistent fever (5 10 days) five hospitals Mexican...

10.1089/vbz.2019.2580 article EN Vector-Borne and Zoonotic Diseases 2020-07-16

Phaseolotoxin is a major virulence factor of the bean pathogen bacterium P. savastanoi pv. phaseolicola. This toxin plays key role in development halo blight disease plants. So far, signal transduction pathways involved synthesis phaseolotoxin have not been elucidated. The influence regulation mechanisms related to oxidative stress response, particular OxyR protein, it has suggested be this process.. In study we evaluated phaseolicola, mainly compared and phytopathogen. Generation...

10.3390/microorganisms10112123 article EN cc-by Microorganisms 2022-10-27

Abstract Introduction: Prostate cancer (CaP) encompasses a range of malignant prostate tissue dysplasias that primarily affects men over 50 years, is the second leading cause mortality in males. VEGF expression associated with tumor progression and metastasis patients CaP. The SNP -1154 G/A severity CaP populations Tunisia United Kingdom while -634 G/C alone has been Tunisian population. It unknown whether these polymorphisms could serve as biomarkers Mexican Aim: To associate - 634 western...

10.1158/1538-7445.am2017-1279 article EN Cancer Research 2017-07-01
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