A5030667295- Adipokines, Inflammation, and Metabolic Diseases
- Natural Antidiabetic Agents Studies
- Adipose Tissue and Metabolism
- Cardiac Ischemia and Reperfusion
- Regulation of Appetite and Obesity
- Temporomandibular Joint Disorders
- Biochemical effects in animals
- Health and Lifestyle Studies
- Systemic Lupus Erythematosus Research
- Oropharyngeal Anatomy and Pathologies
- Genomic variations and chromosomal abnormalities
- Advances in Cucurbitaceae Research
- Orthodontics and Dentofacial Orthopedics
- Inflammatory Myopathies and Dermatomyositis
- Drug Transport and Resistance Mechanisms
- Diabetes and associated disorders
- Family and Matrimonial Law
- Cholesterol and Lipid Metabolism
- Chromosomal and Genetic Variations
- Wound Healing and Treatments
- Diverse Scientific Research Studies
- Bipolar Disorder and Treatment
- Blood Coagulation and Thrombosis Mechanisms
- Vitamin K Research Studies
- Mitochondrial Function and Pathology
Universidad de Guadalajara
2003-2020
Center for Rheumatology
2007
We evaluated the association between anti-cyclic citrullinated peptide antibodies (anti-CCP) and anti-mutated vimentin (anti-MCV) with presence of extra-articular (ExRA) manifestations in 225 patients rheumatoid arthritis (RA). Ninety-five had ExRA 130 no ExRA. There was anti-CCP anti-MCV levels as total group (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.40</mml:mn></mml:math>and<mml:math...
Abstract Background Patients with type 2 diabetes mellitus (T2DM) are characterized by chronic hyperglycemia as a consequence of decreased insulin sensitivity, which contributes to bone demineralization and could also be related changes in serum levels osteocalcin insulin, particularly when coupled deficiency the daily consumption vitamins D3 K2. The objective this study was evaluate effect vitamin K2 supplements alone or combination on metabolic parameters patients T2DM. Methods A...
Aim: To evaluate whether a combination of isosorbide dinitrate spray and chitosan gel (10%) topically applied can have additive benefits for management diabetic foot ulcers. Methods: In randomized, placebo-controlled, double-blinded clinical trial, 68 patients were divided into four groups: Group 1: treated with gel; 2: spray; 3: 4: placebo. Results: Histological analyses showed significant regeneration in all groups ( p < 0.001). On the final assessment ulcer, using was found wound...
Breast cancer is the most common in women worldwide. Approximately 70% of female breast patients have a body mass index (BMI) >25. In obesity, adipose tissue secretes additional resistin, which prompts proinflammatory effect through its action on adenylate cyclase-associated protein 1 (CAP1). Several studies associated RETN gene single nucleotide polymorphism (SNP) rs1862513 (-420C<G) with serum resistin levels and cancer. The CAP1 SNP rs35749351 (missense, Arg294His), located extracellular...
Abstract. Naringin is a citrus-flavonoid which has been shown to have positive metabolic and anti-inflammatory effects. For this reason, we believe it would be interesting study the effects of administration on body weight, BMI, lipid profile adiponectin levels in patients with dyslipidemia, especially considering that dyslipidemias along obesity subsequent cardiometabolic complications are some most important public health issues plaguing our society today. A double-blind, randomized...
Abstract Seckel syndrome (SS) is an autosomal recessive entity characterized by proportionate pre‐ and post‐natal growth retardation, microcephaly, typical facial appearance with beak‐like protrusion, severe mental retardation. A heterogeneous basis for SS was proposed since around 25% of patients have hematological anomalies, suggesting a subgroup chromosome instability disorders. Chromosome induced mitomycin C (MMC) has been observed in previous reports. The purpose this study to report...
We describe a family with 7-year-old proband case diagnosed systemic lupus erythematosus (SLE) plus secondary anti-phospholipid syndrome (APS) as well two affected paternal aunts. compared the frequency of these polymorphisms healthy controls.To evaluate mode inheritance in this familial APS and SLE possible association plasminogen activator inhibitor-1 (PAI-1) -675 4G/5G PAI-2 Ser(413)/Cys polymorphisms. To compare genotype results found Mexican Mestizo population.PAI-1 were determined by...
The therapeutic effects of telmisartan, an angiotensin II receptor antagonist and a peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist, have been demonstrated in several disorders. It has antioxidant immune response modulator properties shown promising results the treatment ischemia/reperfusion (I/R) lesion. In this study, skeletal muscle (right gastrocnemius muscle) I/R lesion was induced rats different reperfusion times (1 h, 24 72 7-day, 14-day subgroups) were assessed....
Uncontrolled proliferation and death resistance are two hallmarks of cancer cells. Breast (BC) has the highest incidence mortality in women worldwide national; subtype triple negative (TN) is most aggressive type because it not susceptible to conventional therapy. Since 2004, World Health Organization (WHO) approved use alternative treatments as adjuvants based on evidence its benefits. then, different natural alternatives treat have been studied, including Origanum vulgare (Ov) carvacrol...
Abstract Background Mitotic configurations consistent in split centromeres and splayed chromatids all or most of the chromosomes premature centromere division (PCD) have been described three categories. (1) Low frequency PCD observed colchicines-treated lymphocyte cultures from normal individuals. (2) High with mosaic variegated aneuploidy. (3) as a sole chromosome abnormality individuals no recognizable clinical pattern. We report four members family third category PCD. Methods Cell cycle...
The aim of this study was to investigate the effects Cassia acutifolia on obesity and glucose levels in a rat model diabetes.By random selection, 36 Wistar male rats were divided two control groups, positive negative into four experimental groups receiving different infusions water ad libitum.The results revealed statistically significant anti-obesogenic effect (P = 0.02), although not considered clinically significant. Additionally, lowered by 30 mg/dL 90 0.05). However, we observed adverse...
Anterior disc displacement with reduction (DDWR) is considered one of the most common disorders within temporomandibular joint (TMJ), a prevalence 41% in adults. Matrix metalloproteinases play an important role degradation TMJ and matrix metalloproteinase 1 (MMP1) 1607 1G/2G polymorphism increases local expression MMP1 thus leading to accelerated extracellular matrix. The objective this study was evaluate association between gene DDWR group Mexican individuals from western Mexico. A total 67...
Background: Adiponectin, encoded by the ADIPOQ gene, is produced mainly adipose tissue, and meaning as a metabolic immunological regulator. The polymorphism rs822396 in gene was previously associated with diabetes mellitus type 2, hypertension, syndrome components Caucasian Asiatic populations. aim to evaluate association of anthropometric, clinical, biochemical alterations related Mexican population. Materials Methods: Measurements, well peripheral blood for DNA extraction, were obtained...
La esquizofrenia es un trastorno mental grave, recientemente asociado a distintas variantes geneticas como el polimorfismo de la enzima Metilenotetrahidrofolato reductasa (MTHFR) C677T. El objetivo fue evaluar asociacion estadistica del MTHFR C677T, con predominancia sintomatologica en una muestra pacientes Jalisco, Mexico. Se realizo estudio descriptivo, transversal, enfoque retrospectivo, donde se analizaron 49 pacientes, quienes fueron clasificados por su escala los Sindromes Positivo y...
Ischemia–reperfusion is defined as cellular damage after the reperfusion of ischemic tissue, and it likely to occur in relation various diseases surgical procedures. The purpose this study was evaluate capability atorvastatin prevent oxidative modulate release proinflammatory cytokines rat hindlimb during ischemia–reperfusion injury. animals were divided into 4 groups (ischemia–reperfusion + vehicle, atorvastatin, sham, healthy controls) with 15 rats per group. exposed ischemia for 6 h,...