A5101896979- Cancer Treatment and Pharmacology
- Sirtuins and Resveratrol in Medicine
- Fungal Infections and Studies
- PARP inhibition in cancer therapy
- Epigenetics and DNA Methylation
- Antifungal resistance and susceptibility
- Reproductive Biology and Fertility
- Autophagy in Disease and Therapy
- Childhood Cancer Survivors' Quality of Life
- Caveolin-1 and cellular processes
- Cancer-related gene regulation
- Renal Diseases and Glomerulopathies
- Lung Cancer Research Studies
- Oral health in cancer treatment
- Endoplasmic Reticulum Stress and Disease
- Long-Term Effects of COVID-19
- Cancer survivorship and care
- Multiple Myeloma Research and Treatments
- FOXO transcription factor regulation
- Peroxisome Proliferator-Activated Receptors
- Sperm and Testicular Function
- Flavonoids in Medical Research
- Protein Degradation and Inhibitors
- Pluripotent Stem Cells Research
- Complement system in diseases
Hangzhou First People's Hospital
2012-2024
Westlake University
2024
Hebei Eye Hospital
2024
Southwest University
2020-2022
State Key Laboratory of Silkworm Genomic Biology
2020-2022
Chongqing Population and Family Planning Science and Technology Research Institute
2021
Guangxi University
2019-2020
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2019-2020
Huazhong University of Science and Technology
2012-2019
Central Hospital of Wuhan
2019
Melanoma, the most aggressive human skin tumor, has a very short survival time, and there are currently no effective treatments. Alterations in cell metabolism, such as enhanced aerobic glycolysis, have been identified hallmarks of cancer cells. In present study, bioinformatics studies using online databases revealed that FOXO3a expression was lower melanoma tissues compared with normal nevus. Additionally, Kaplan‑Meier analysis showed high predicted an improved prognosis for patients...
Objective: Gastric cancer is one of the most common malignant tumors. Bruceine D (BD) extracts Brucea javanica . In recent years, it has been reported that BD anti-tumor activity in some human cancers through different mechanisms. Here, this study try to explore effect on gastric and its regulatory mechanism. Methods: Cell proliferation ability was detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assays, 5-bromo-2-deoxyuridine (BrdU) staining soft agar colony...
Oxygenase-catalyzed reduction and activation of oxygen molecules the incorporation atoms into organic are undoubtedly necessary in process tumor development, it is also one research hotspots recent years. MOXD1 belongs to copper-dependent monooxygenase family. The expression characteristics early development. However, not understandable that biological function molecular mechanism Glioblastoma (GBM). In this study, high strongly associated with poor survival patient GBM. Moreover. knockdown...
The objectives of present study were to evaluate the effect casein kinase 1 (CK1) inhibition D4476 on in vitro maturation (IVM) and developmental competence bovine oocytes. cumulus oocyte complexes (COCs) cultured medium with (0, 2, 5, 10, 20 μM) for 24 hr. After IVM fertilization, through expansion average scores cells (CCs), efficiency, cleavage rate blastocyst zygote, we found 5 μM could increase development potential COCs treated D4476, results quantitative real-time PCR analysis, Lichen...
Abstract This study mainly explored the effects of Rapamycin on growth Buffalo ear fibroblast (BEF) and embryonic developmental competence somatic cell nuclear transfer (SCNT). The results show that appropriate concentration (1 μM) could significantly improve proportion G0/G1 phase in BEF cells treated at a certain time (72 hr). Simultaneously, percentage also was higher than serum starvation control group. may be related to inhibiting phosphorylation mTOR affecting expression cycle‐related...
This experiment was designed to evaluate the potential for dietary alfalfa saponins (AS) influence cholesterol (Ch) concentrations and mRNA expressions of ATP-binding cassette (ABC) that concludes transporters G5 (ABCG5) G8 (ABCG8) in livers laying hens. Hundred fifty hens (27 weeks old) were divided into five treatment groups randomly. Five replicates assigned each group consisting six birds per replicate. The same basic diet used all with supplementation 0 (control), 60, 120, 240, 480...
A subtype of the Omicron variant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is suggested to be responsible for outbreak in Northern China since quarantine was lifted December 2022. The disease 2019 virus primarily development illnesses, however, it can present a plethora symptoms affecting myriad body organs. This has been theorized linked demyelinating lesions peripheral and central nervous system including transverse myelitis retrobulbar optic neuritis (ARON). For...
Objective To study the effect of sodium valproate (VPA) on expression NKG2D ligands MICA and MICB in pancreatic cancer cells.Methods Pancreatic cells were incubated with 1 mmol/L VPA for 24 h,then,flow cytometry real-time quantitative polymerase chain reaction (Real-time PCR) used to detect MICA/B PC-2 BxPC-3 VPA-treated group control group.Results The positive rate was 1.2％ -1.5％ 37.4％ -42.5％ ; 3.2％ -4.1％ 62.4％ -77.2％ after treatment.The mRNA level 1.183 ±0.219 3.790 ± 0.519,and 1.020...