A5053563699- COVID-19 epidemiological studies
- Global Maternal and Child Health
- Vaccine Coverage and Hesitancy
- Data-Driven Disease Surveillance
- Child Nutrition and Water Access
- HIV Research and Treatment
- Global Health Care Issues
- HIV/AIDS Research and Interventions
- Immune Cell Function and Interaction
- Global Public Health Policies and Epidemiology
- T-cell and B-cell Immunology
- Healthcare Systems and Reforms
- Poverty, Education, and Child Welfare
- Food Security and Health in Diverse Populations
- Autopsy Techniques and Outcomes
- Zoonotic diseases and public health
- Obesity, Physical Activity, Diet
- Employment and Welfare Studies
- Influenza Virus Research Studies
- HIV, Drug Use, Sexual Risk
- Virology and Viral Diseases
- Viral Infections and Outbreaks Research
- COVID-19 Clinical Research Studies
- Youth Education and Societal Dynamics
- Agricultural risk and resilience
Instituto Nacional de Saúde
2017-2025
Manhiça Health Research Centre
2023-2024
Ministry of Health
2018-2024
Emory University
2023
Ludwig-Maximilians-Universität München
2021-2022
African Union
2019
Africa Centres for Disease Control and Prevention
2019
Johns Hopkins University
2019
Gates Foundation
2019
Mozambique faces a high burden of infectious diseases but currently has limited capacity for forecasting disease incidence. Recent improvements in surveillance through the National Monitoring and Evaluation System now provide weekly reports incidence across country's districts. This study focuses on using these records, specifically malaria diarrhoeal diseases, which together account approximately 40% deaths among children under five, to develop statistical forecasts evaluate their accuracy....
The 2019 emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its rapid spread created a public health emergency international concern. However, the impact pandemic in Sub-Saharan Africa, as documented cases, hospitalizations deaths, appears far lower than Americas, Europe Asia. Characterization transmission dynamics is critical for understanding how SARS-CoV-2 spreads true scale pandemic. Here, to better understand two southern African countries, Mozambique...
Sub-Saharan Africa lacks timely, reliable, and accurate national data on mortality causes of death (CODs). In 2018 Mozambique launched a sample registration system (Countrywide Mortality Surveillance for Action [COMSA]-Mozambique), which collects continuous birth, death, COD from 700 randomly selected clusters, nationally representative population 828,663 persons. Verbal social autopsy interviews are conducted determination. We analyzed collected in 2019-2020 to report rates cause-specific...
The Countrywide Mortality Surveillance for Action platform is collecting verbal autopsy (VA) records from a nationally representative sample in Mozambique. These are used to estimate the national and subnational cause-specific mortality fractions (CSMFs) children (1-59 months) neonates (1-28 days). Cross-tabulation of VA-based cause-of-death (COD) determination against that minimally invasive tissue sampling (MITS) Child Health Prevention project revealed important misclassification errors...
The acute phase of HIV infection is characterized by massive depletion CD4 T cells, high viral plasma levels and pronounced systemic immune activation. Regulatory cells (Tregs) have the potential to control activation but also suppress antigen specific B cell response. co-expression FoxP3 Helios transcription factors, has been described for identification highly suppressive Tregs. aim this study was characterize phenotype classic Tregs during early infection, assess correlations between...
Integrated disease surveillance (IDS) offers the potential for better use of data to guide responses public health threats. However, extent IDS implementation worldwide is unknown. This study sought understand how operationalized, identify challenges and barriers, opportunities development. Synthesis qualitative studies undertaken in seven countries. Thirty-four focus group discussions 48 key informant interviews were Pakistan, Mozambique, Malawi, Uganda, Sweden, Canada, England, with...
The 2019 emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its rapid spread created a public health emergency international concern. However, the impact pandemic in Sub-Saharan Africa, as documented cases, hospitalizations deaths, appears far lower than Americas, Europe, Asia. Characterization transmission dynamics is critical for understanding how SARS-CoV-2 true scale pandemic. Here, to better understand two southern African countries, Mozambique Zimbabwe, we...
1. Abstract Introduction There are few sources of empirical social contact data from resource-poor settings thus limiting the development contextual mathematical models disease transmission and control. Methods We collected analyzed cross-sectional survey rural urban sites in Mozambique. Participants, including infants, were recruited. They reported retrospectively, a paper diary, individuals with whom they had co-located physical or conversation contact, as well their age, sex,...
Background Low-and-middle-income countries (LMICs) bear a disproportionate burden of communicable diseases. Social interaction data inform infectious disease models and prevention strategies. The variations in demographics contact patterns across ages, cultures, locations significantly impact dynamics pathogen transmission. LMICs lack sufficient social for modeling. Methods To address this gap, we will collect qualitative quantitative from eight study sites (encompassing both rural urban...
As one of several countries that pledged to achieve the Millennium Development Goals (MDGs), Mozambique sought reduce child, neonatal, and maternal mortality by two thirds 2015. This study examines impact Mozambique's efforts between 1997 2015, highlighting increases in intervention coverage contributed saving most lives.A retrospective analysis available household survey data was conducted using Lives Saved Tool (LiST). Baseline rates, cause-of-death distributions, interventions were...
Since March 2018, the Countrywide Mortality Surveillance for Action project, implemented as a national sample registration system by Mozambique Instituto Nacional de Saude and Estatistica in 700 geographic clusters randomly distributed across 11 provinces, has trained deployed community surveillance agents (CSAs) to report births deaths each cluster prospectively. An independent, retrospective data collection was conducted assess completeness of data. Record linkage procedures were used...
Introduction Mozambique continues to have a significant burden of HIV. Developing strategies control the HIV epidemic remains key priority for Mozambican public health community. The primary aim this study was determine prevalence and risk behavior among males females screened vaccine preparedness in Maputo, Mozambique. Methods Male female participants between 18–35 years old were recruited from general community sex worker (FSW) lesbian, gay, bisexual, transgender (LGBT) associations...
This study was performed to describe physical activity behavior and its demographic associations in a peri-urban population from Mozambique, using device-based data.Physical assessed by pedometers sample of 15- 64-year-old subjects Maputo, Mozambique. Participants wore pedometer for 7 consecutive days, inactivity classified variety approaches: sedentary (<5000 steps/d), physically inactive (<7500 no moderate-to-vigorous (MVPA < 1 min/d).The percentage 17.8%, the who were 41.8%. A total 9.0%...
Background Overweight and obesity are important risk factors for non-communicable diseases (NCDs) such as cardiovascular (CVD), type 2 diabetes certain cancers.NCDs responsible an increased number of deaths worldwide, including in developing countries.We aimed to determine the prevalence overweight among youth adults a peri-urban area Maputo city, Mozambique, assess their social behavioral determinants.Methods A cross-sectional study was conducted Health Demographic Surveillance System...
Circumcision is a protective measure against sexually transmitted infections (STIs), reducing the risk of HIV infection. This study reported coverage male circumcision and assessed factors associated with uncircumcision in peri-urban area Maputo City, Mozambique. cross-sectional Health Demographic Surveillance System Polana Caniço neighborhood investigated sociodemographic behavioral uncircumcised males aged 15-49 y from October 2019 to June 2021. Data were collected an questionnaire...
In sub-Saharan Africa, reported COVID-19 numbers have been lower than anticipated, even when considering populations' younger age. The extent to which risk factors, established in industrialised countries, impact the of infection and disease populations remains unclear. We estimated incidence mild moderate urban Mozambique analysed factors associated with a population-based surveillance study. During December 2020-March 2022, 1,561 households (6,049 participants, median 21 years, 54.8%...
Few sources have reported empirical social contact data from resource-poor settings. To address this shortfall, we recruited 1,363 participants rural and urban areas of Mozambique during the COVID-19 pandemic, determining age, sex, relation to for each person. Participants a mean 8.3 (95% CI 8.0-8.6) contacts per The rates were higher in site compared with (9.8 vs 6.8; p<0.01). Using mathematical models, noted vaccine effects when comparing (32%) synthetic (29%) matrices lower corresponding...