A5061900944- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Pneumonia and Respiratory Infections
- COVID-19 Pandemic Impacts
- COVID-19 and Mental Health
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- Influenza Virus Research Studies
- COVID-19 Clinical Research Studies
- Herpesvirus Infections and Treatments
- Virology and Viral Diseases
- Viral Infections and Outbreaks Research
- COVID-19 and healthcare impacts
- Misinformation and Its Impacts
- ICT in Developing Communities
- Animal Disease Management and Epidemiology
- Employment and Welfare Studies
- Global Health Care Issues
- Bacterial Infections and Vaccines
- Infection Control and Ventilation
- Poverty, Education, and Child Welfare
- Gastroesophageal reflux and treatments
- HIV/AIDS Impact and Responses
- Emergency and Acute Care Studies
- Immune responses and vaccinations
Bocconi University
2016-2025
University of Warwick
2002-2019
Institute for Scientific Interchange
2019
London School of Hygiene & Tropical Medicine
2019
Hospital for Tropical Diseases
2019
Kenya Medical Research Institute
2019
Public Health England
2005-2009
University of California, Berkeley
2008
Queen Mary University of London
2007
University College London
2007
In the night of February 20, 2020, first case novel coronavirus disease (COVID-19) was confirmed in Lombardy Region, Italy. week that followed, experienced a very rapid increase number cases. We analyzed 5,830 laboratory-confirmed cases to provide epidemiological characterization COVID-19 outbreak Western Country. Epidemiological data were collected through standardized interviews and their close contacts. demographic backgrounds, dates symptom onset, clinical features, respiratory tract...
Background Understanding public perceptions of government responses to COVID-19 may foster improved cooperation. Trust in and population risk exposure influence perception the response. Other population-level characteristics, such as country socio-economic development, morbidity mortality, degree democratic government, perception. Methods findings We developed a novel ten-item instrument that asks respondents rate key aspects their government's response pandemic (COVID-SCORE). examined...
In the night of February 20, 2020, first epidemic novel coronavirus disease (COVID-19) outside Asia was uncovered by identification its patient in Lombardy region, Italy. following weeks, experienced a sudden increase number ascertained infections and strict measures were imposed to contain spread.We analyzed official records cases occurred characterize epidemiology SARS-CoV-2 during early phase outbreak. A line list laboratory-confirmed set up later retrospectively consolidated, using...
Solid estimates of the risk developing symptoms and progressing to critical disease in individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are key interpreting 2019 (COVID-19) dynamics, identifying settings segments population where transmission is more likely remain undetected, defining effective control strategies.To estimate association age likelihood illness after SARS-CoV-2 infection.This cohort study analyzed quarantined case contacts, identified...
BackgroundNatural immunity to Streptococcus pneumoniae is thought be induced by exposure S. or cross-reactive antigens. No longitudinal studies of carriage and immune responses have been conducted using sophisticated immunological laboratory techniques
A 10-month longitudinal household study of pre-school children and their families was undertaken with monthly visits collecting epidemiological data nasopharyngeal swabs in Hertfordshire, England from 2001 to 2002. Pneumococcal culture standard methods. In total, 121 (489 individuals) took part. Mean prevalence carriage ranged 52% for age groups 0–2 years, 45% 3–4 21% 5–17 years 8% [ges ]18 years. Carriage occurred more than once 86% aged compared 36% those The most prevalent serotypes the...
Knowledge of the determinants infectious disease transmission is a public health priority as it allows design optimal control strategies for endemic or emerging infections. We analyse detailed dataset on contact patterns across five European countries and use available serological profiles varicella parvovirus B19 infections to identify types that may be most relevant transmission. show models informed by data fit well observed both find intimate contacts explain pattern acquisition markers...
Patterns of person-to-person contacts relevant for infectious diseases transmission are still poorly quantified in Sub-Saharan Africa (SSA), where socio-demographic structures and behavioral attitudes expected to be different from those more developed countries.We conducted a diary-based survey on daily time-use individuals ages one rural peri-urban site Manicaland, Zimbabwe. A total 2,490 diaries were collected used derive age-structured contact matrices, analyze time spent by settings,...
We analyzed 5,484 close contacts of COVID-19 cases from Italy, all them tested for SARS-CoV-2 infection. found an infection fatality ratio 2.2% (95%CI 1.69-2.81%) and identified male sex, age >70 years, cardiovascular comorbidities, early in the epidemics as risk factors death.
Identifying health care settings and professionals at increased risk of SARS-CoV-2 infection is crucial to defining appropriate strategies, resource allocation, protocols protect workers (HCWs) patients. Moreover, such information decrease the that HCWs facilities become amplifiers for transmission in community.To assess association different professional categories operational units, including in-hospital wards, outpatient facilities, territorial departments, with seroprevalence odds...
This paper analyses Streptococcus pneumoniae transmission dynamics in households using longitudinal data on pneumococcal (Pnc) carriage the United Kingdom. Ten consecutive swabs were taken at 4-week intervals from all members of 121 households. The family status is derived observed Pnc each member. Transition matrices are built for size and composition containing frequency transitions between statuses over a 28-day interval. A density-dependent model fitted to derive maximum-likelihood...
Social contact patterns are a critical explanatory factor of the spread close-contact infectious agents. Both indirect (via observed epidemiologic data) and direct diaries that record at-risk events) approaches to measurement contacts by age have been proposed in literature. In this paper, authors discuss possibilities offered time-use surveys measure explain seroprevalence profiles. The first develop methodology estimate time-of-exposure matrices, then they apply it data for United States...
Abstract Background The 7-valent pneumococcal conjugate vaccine has been introduced in national immunisation programmes of most industrialised countries and recently two African GAVI eligible (Rwanda Gambia). However the long term effects PCV are still unclear, as beneficial direct herd immunity might be countered by serotype replacement. Method A dynamic, age-structured, compartmental model Streptococcus pneumoniae transmission was developed to predict potential impact PCV7 on incidence...
The introduction of mass vaccination against Varicella-Zoster-Virus (VZV) is being delayed in many European countries because of, among other factors, the possibility a large increase Herpes Zoster (HZ) incidence first decades after initiation vaccination, due to expected decline boosting Cell Mediated Immunity caused by reduced varicella circulation. A multi-country model VZV transmission and reactivation, used evaluate possible impact on HZ epidemiology Italy, Finland UK. Despite...