A5058708414- Tuberculosis Research and Epidemiology
- HIV/AIDS Research and Interventions
- Mental Health Treatment and Access
- Adolescent Sexual and Reproductive Health
- HIV, Drug Use, Sexual Risk
- Schizophrenia research and treatment
- HIV/AIDS Impact and Responses
- Pneumonia and Respiratory Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV Research and Treatment
- Healthcare professionals’ stress and burnout
- Family Caregiving in Mental Illness
- Antibiotic Use and Resistance
- Adolescent and Pediatric Healthcare
- Infectious Diseases and Tuberculosis
- Mycobacterium research and diagnosis
- HIV-related health complications and treatments
- Global Maternal and Child Health
- COVID-19 and Mental Health
- Health, psychology, and well-being
Zambart
2019-2024
University of Zambia
2019-2024
Faculty of Public Health
2023
London School of Hygiene & Tropical Medicine
2021-2023
To describe the prevalence and determinants of HIV stigma in 21 communities Zambia South Africa.Analysis baseline data from HPTN 071 (PopART) cluster-randomized trial. came a random sample 3859 people living with HIV. Community-level exposures reflecting fears judgements perceptions community members not (n = 5088), health workers (HW) 851).We calculated internalized stigma, experienced or healthcare setting past year. We conducted risk-factor analyses using logistic regression, adjusting...
WHO recommends community-wide, systematic tuberculosis screening in high-prevalence settings. C-reactive protein has been proposed as a tool for people living with HIV. We aimed to assess the performance of point-of-care test community two countries high burden.
Integrating standardized measures of HIV stigma and discrimination into research studies emerging prevention approaches could enhance uptake retention these approaches, care treatment for people living with (PLHIV), by informing mitigation strategies. We sought to develop a succinct set capture key domains use in on technologies.
Abstract People with tuberculosis (TB) are susceptible to mental distress. Mental distress can be driven by biological and socio-economic factors including poverty. These persist beyond TB treatment completion yet there is minimal evidence about the health of survivors. A cross-sectional prevalence survey adults was conducted in an urban community Zambia. Survey participants were administered five-item Self Reporting Questionnaire (SRQ-5) screening tool measure Associations between primary...
The impact of HIV stigma on viral suppression among people living with (PLHIV) is not well characterized.Twenty-one communities in Zambia and South Africa, nested within the HPTN 071 (PopART) trial.We analyzed data (<400 copies RNA/mL) 5662 laboratory-confirmed PLHIV aged 18-44 years who were randomly sampled PopART trial population cohort 24 months after enrolment (PC24). We collected experiences internalization from those self-reported their status (n = 3963/5662) perceptions a 20% random...
Objectives Prevalence surveys remain the best way to assess national tuberculosis (TB) burden in many countries. Challenges with using culture (the reference standard) for TB diagnosis prevalence have led increasing use of molecular tests (Xpert assays), but discordance between these two has created problems deciding which individuals TB. We aimed design an accurate diagnostic algorithm (TBPS) that limits culture. Design TBPS four communities, conducted during 2019. Setting Three Zambian...
To assess the impact of a combination HIV prevention intervention including universal testing and treatment (UTT) on stigma among people living with HIV, community members health workers not HIV.This study was nested in HPTN 071 (PopART) trial, three-arm cluster randomised trial conducted between 2013 2018 21 urban/peri-urban communities (12 Zambia nine South Africa).Using an adjusted two-stage cluster-level analysis, controlling for baseline imbalances, we compared multiple domains arms at...
The global expansion of HIV testing, prevention and treatment services is necessary to achieve epidemic control promote individual population health benefits for people living with (PLHIV) in sub-Saharan Africa. Community-based workers (CHWs) could play a key role supporting implementation at scale. In the HPTN 071 (PopART) trial Zambia South Africa, cadre 737 study-specific CHWs, working closely government-employed CHW, were deployed deliver 'universal' door-to-door package, including an...
Abstract Background In the high disease burden and resource-constrained contexts of sub-Saharan Africa (SSA), health workers experience a range psychosocial stressors that leave them vulnerable to developing burnout, which can reduce service quality negatively impact their own wellbeing. As universal testing treatment (UTT) for HIV scales up across SSA, we sought understand implications this human resource-intensive approach prevention inform decision-making about workforce staffing support...
The WHO estimates 58 million people experienced one or more TB disease episodes between 2000 and 2018. These 'former patients' are at greater risk of future infection death than naïve people. Additionally, former patients experience social, psychological, physiological difficulties after microbiological cure. Drawing on semi-structured interviews collected with 28 from communities in Zambia (n = 8) South Africa 2) October 2018 March 2019, we describe their perceptions having two episodes....
In recent years, there has been increased recognition of the need to integrate mental health services into routine tuberculosis (TB) care. For successful integration, policymakers first understand practices TB workers in management conditions, including depression, anxiety, and psychological distress, use this decide how best could be delivered tandem with services. qualitative study we aimed other stakeholders viewed conditions linked they screened treated these their patients.The draws on...
Abstract Introduction To investigate the association between individual and community‐level measures of HIV stigma incidence within 21 communities participating in HPTN (071) PopART trial Zambia South Africa. Methods Secondary analysis data from a population‐based cohort followed‐up over 36 months 2013 2018. The outcome was rate incident infection among individuals who were negative at entry. Individual‐level exposures, measured random sample all participants, were: (1) perception community,...
Background Mental health is a critical and neglected public problem for adolescents in sub-Saharan Africa. In this paper we aim to determine the prevalence of depressive symptoms association with HIV risk behaviours aged 15–19 years Zambia SA. Methods We conducted cross-sectional survey from August-November 2017 seven control communities HPTN 071 (PopART) trial (a community-randomised universal testing treatment), enrolling approximately 1400 eligible adolescents. HIV-status was...
Abstract People living with HIV (PLHIV) report lower health-related quality-of-life (HRQoL) than HIV-negative people. stigma may contribute to this. We explored the association between and HRQoL among PLHIV. used cross-sectional data from 3991 randomly selected PLHIV who were surveyed in 2017–2018 for HPTN 071 (PopART), a cluster randomised trial Zambia South Africa. Participants 18–44 years, had laboratory-confirmed infection, knew their status. was measured using...
The mental health and TB syndemic is a topic that remains under-researched with significant gap in acknowledging recognizing patient experiences, particularly the sub-Saharan African region. In this qualitative study conducted Zambia, we aimed to explore lived experiences of patients focusing on their multi-layered drivers distress, by so doing highlighting contextual factors influence distress setting. draws data collected 2018 as part Tuberculosis Reduction through Expanded Antiretroviral...