A5031905516- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Bone Tissue Engineering Materials
- 3D Shape Modeling and Analysis
- Bone health and osteoporosis research
- Orthopaedic implants and arthroplasty
- Pelvic and Acetabular Injuries
- Orthodontics and Dentofacial Orthopedics
- Face recognition and analysis
- Facial Rejuvenation and Surgery Techniques
- Additive Manufacturing and 3D Printing Technologies
- Musculoskeletal pain and rehabilitation
- Electrospun Nanofibers in Biomedical Applications
- Shoulder Injury and Treatment
- Craniofacial Disorders and Treatments
- Elasticity and Material Modeling
- Bone fractures and treatments
- Anatomy and Medical Technology
- Dental Radiography and Imaging
- 3D Printing in Biomedical Research
- Facial Trauma and Fracture Management
- Temporomandibular Joint Disorders
- Cellular and Composite Structures
- Automotive and Human Injury Biomechanics
Baylor College of Medicine
2012-2024
Michael E. DeBakey VA Medical Center
2011-2021
Houston Methodist
2017
Exponent (United States)
2014-2015
Rice University
2001-2008
Whitaker Center for Science and the Arts
2004
The University of Texas MD Anderson Cancer Center
2004
University of California, Berkeley
1999-2002
Biomechanics Institute of Valencia
2001
University of California System
1999
Study Design. The biomechanical behavior of a single lumbar vertebral body after various surgical treatments with acrylic vertebroplasty was parametrically studied using finite-element analysis. Objectives. To provide theoretical framework for understanding and optimizing the biomechanics vertebroplasty. Specifically, to investigate effects volume distribution bone cement on stiffness recovery body. Summary Background Data. Vertebroplasty is treatment that stabilizes fractured vertebra by...
Biomechanical properties within cadaveric vertebral bodies were parametrically studied using finite element analysis after calibration to experimental data.To develop and validate three-dimensional models of the human thoracolumbar spine based on quantitative computed tomography scans. Specifically, combine modeling together with biomechanical testing circumventing problems associated direct measurements shell properties.Finite methods can help understand injury mechanisms stress...
Orthognathic surgery corrects jaw deformities to improve aesthetics and functions. Due the complexity of craniomaxillofacial (CMF) anatomy, orthognathic requires precise surgical planning, which involves predicting postoperative changes in facial appearance. To this end, most conventional methods involve simulation with biomechanical modeling methods, are labor intensive computationally expensive. Here we introduce a learning-based framework speed up appearances. Specifically, shape change...
This study focused on the assessment of radiography, microcomputed tomography, and histology for evaluation bone formation in a 15.0-mm defect rabbit radius after implantation tissue-engineered construct. Radiography was found to be useful as noninvasive method obtaining images calcified tissue throughout time course experiment. With this method, however, image quality low, making it difficult obtain precise information about location quantity formed. Microcomputed tomography used create...
To aid in the development of scaffolds for tissue engineering, we propose a library architectures (unit primitives) that may be strategically merged according to various characteristics. In particular, bone, mechanical characteristics such as regional stiffness, micro-architectural levels surface strain, void fraction amount and orientation, well permeability other parameters will critical both individually concert. As relationships between aforementioned are elucidated, potential...
In Brief Study Design. The effects of bone cement placement, volume, and density on the degree biomechanical reinforcement cadaveric vertebral bodies were studied using experimentally calibrated detailed finite element models. Objectives. To investigate efficacy prophylactic vertebroplasty intact with respect to recovery fracture risk reduction. Summary Background Data. Vertebroplasty is a potentially effective prevention treatment, but complications due leakage must be minimized. Therefore,...
It is clinically important to accurately predict facial soft-tissue changes prior orthognathic surgery. However, the current simulation methods are problematic, especially in anatomic regions of clinical significance, e.g., nose, lips, and chin. We developed a new 3-stage finite element method (FEM) approach that incorporates realistic tissue sliding improve such prediction.In Stage One, change was simulated, using FEM with patient-specific mesh models generated from our previously eFace...
This study investigated the in vitro degradation characteristics of macroporous hydrogels based on poly(propylene fumarate-co-ethylene glycol) (P(PF-co-EG)). Four formulations were fabricated to test effect porosity and cross-linking density resulting hydrogels. Macroporosity was introduced by addition sodium bicarbonate ascorbic acid, precursors carbon dioxide porogen, initiation system for hydrogel cross-linking. Macroporous with porosities 0.80 +/- 0.03 0.89 synthesized concentrations 40...
There is an increased incidence of fractures in untreated adjacent vertebrae after vertebroplasty.To introduce unconstrained 6 degrees freedom biomechanical testing to investigate whether vertebroplasty lowered the fracture strength under physiological loading conditions and describe observed pattern.Three-level spinal segments (T10-12 L1-3) from spines were tested axial compression which shear forces torque minimized using a 6-degrees robotic arm. Fracture initiation loads ultimate failure...
We sought to test the hypothesis that a pedicle screw has two parallel threads of different heights throughout full length could increase both bone purchase and pullout strength compared with standard single-threaded similar dimensions. A double-threaded were respectively placed into paired pedicles 21 vertebral bodies. The screws then pulled out pedicles, output parameters measured. Although insertional torque was, on average, 14.5% higher (p = 0.039) for screw, maximum 0.12),...
In Brief Study Design: An in vitro flexibility study of the human thoracolumbar spine under compressive preload. Objective. To attain kinematics descriptive by applying a pure bending moment range physiologic preloads. Summary Background Data. Many studies on mechanical behavior have been conducted; however, little is known regarding variations motion attributable to simulated body weight and other load conditions. Methods. Five fresh cadaveric specimens (T9–L3) were used. axial preloads...