A5073401724- Curcumin's Biomedical Applications
- RNA Interference and Gene Delivery
- Cancer Research and Treatments
- Cancer Cells and Metastasis
- Helicobacter pylori-related gastroenterology studies
- MicroRNA in disease regulation
- Biopolymer Synthesis and Applications
- Cancer-related molecular mechanisms research
- Galectins and Cancer Biology
- Bioactive Compounds and Antitumor Agents
- Nanocomposite Films for Food Packaging
- Biosensors and Analytical Detection
- Cancer-related Molecular Pathways
- RNA Research and Splicing
- Veterinary medicine and infectious diseases
- Bacteriophages and microbial interactions
- Wnt/β-catenin signaling in development and cancer
- Advanced biosensing and bioanalysis techniques
- RNA modifications and cancer
- Polyamine Metabolism and Applications
- Freezing and Crystallization Processes
- Potato Plant Research
- Retinoids in leukemia and cellular processes
- Neutropenia and Cancer Infections
- Colorectal Cancer Screening and Detection
Tehran University of Medical Sciences
2015-2020
Tarbiat Modares University
2015-2017
Colon cancer is one of the leading causes cancer-associated death worldwide. The prognosis for advanced colorectal cancers remains dismal, mainly due to propensity metastatic progression. Accordingly, there a need effective anti-metastasis therapeutic agents. Since great body research has indicated anticancer effects curcumin, we investigated dendrosomal curcumin (DNC) on cellular migration and adhesion human SW480 cells possible molecular mechanisms involved. Different methods were applied...
Curcumin is a hydrophobic polyphenol extracted from the plant curcuma longa with establishedanticancer properties. However, curcumin benefits have been impaired by its very low watersolubility, absorption, rapid metabolism and clearance body. Recently,nanotechnology promises to be helpful in development of drugs delivery systems recentadvances macromolecular design nanocarriers. In this review, we present novelgeneration nano-vehicles termed dendrosomes which are readily synthesized...
Despite the good results of anticancer activities by curcumin, there are some hurdles that limit use curcumin as an agent. Many methods were examined to overcome this defect like dendrosomal (DNC). There is increasing evidence miRNAs play important roles in biological processes. In study, we focus on microRNA-21 anti-cancer effects DNC breast cancer.
Purpose: Helicobacter pylori is a widely distributed gram-negative bacterium that infects the human stomach and duodenum.HpaA H. pylori-specific lipoprotein has been shown to be an effective protective antigen against infection.HpaA of as vaccine fully competent for stimulation immune responses.The aim this project cloning, expression, purification flagellar sheath adhesion in Escherichia coli host by fast protein liquid chromatography (FPLC) vaccination target. Materials Methods:The hpaA...
Objective(s): Breast cancer imposes a highest rate of malignancy among the women all around world. Chitin and its derivatives such as D-glucosamine-carboxymethyl chitin Di-hydroxy propyl have immune-modulating effects influence on innate acquisitive immunity which lead to cell activity enhancement. The aim this study was investigating effect D-glucosamine nanoparticle immune responses changes in cytokines type 1 2 level tumoral mice. Methods: Nanoparticles were synthesized by ionic gelation...