A5057092549- COVID-19 and Mental Health
- Healthcare professionals’ stress and burnout
- Liver Disease Diagnosis and Treatment
- Resilience and Mental Health
- Chemical Synthesis and Analysis
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Posttraumatic Stress Disorder Research
- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Ferroptosis and cancer prognosis
- Asymmetric Synthesis and Catalysis
- Disaster Response and Management
- Child and Adolescent Psychosocial and Emotional Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Employment and Welfare Studies
- Alcohol Consumption and Health Effects
- Sphingolipid Metabolism and Signaling
- Fluorine in Organic Chemistry
- Peptidase Inhibition and Analysis
- Click Chemistry and Applications
- Adipose Tissue and Metabolism
- Carbohydrate Chemistry and Synthesis
- Diabetes Treatment and Management
- Lipid metabolism and disorders
Southern Medical University
2018-2024
South China University of Technology
2024
Guangdong Provincial People's Hospital
2024
Guangdong Academy of Medical Sciences
2024
Zhujiang Hospital
2023
TCM-Intigrated Cancer Center of Southern Medical University
2022-2023
Affiliated Hospital of Southwest Medical University
2023
Zhoukou City Academy of Agricultural Sciences
2023
United States Department of the Navy
2020-2023
Second Military Medical University
2008-2022
Purposes During the outbreak of Coronavirus Disease 2019 (COVID-19) all over world, mental health conditions care workers are great importance to ensure efficiency rescue operations. The current study examined effect social support on and its underlying mechanisms regarding mediating role resilience moderating age during epidemic. Methods Social Support Rating Scale (SSRS), Connor-Davidson Resilience scale (CD-RISC) Symptom Checklist 90 (SCL-90) were administrated among 1472 from Jiangsu...
Background & AimsAcute liver failure (ALF) is a condition with high mortality and morbidity, characterized by glutathione depletion, oxidative stress, mitochondrial dysfunction. Ferroptosis may be involved in ALF. Indeed, emerging studies have shown that ferroptosis plays significant role However, the mechanism of hepatocytes during ALF remains unknown.MethodsHepatic-specific transforming growth factor β receptor 1 knockout (TGFβr1Δhep-CKO) mice nuclear erythroid 2-related 2 (Nrf2-/-) were...
A tendency to selectively process a threat positive information may be involved in the etiology of anxiety disorders. The aim this study is examine whether attentional bias modification (ABM) can used modify high test-anxiety individuals' attention emotional and change related vulnerability. Seventy-seven undergraduates were included: 28 individuals received 5-day modified dot probe task as ABM training, 29 classic placebo, 20 did not receive an intervention between two test sections. In...
The ability to identify emotions from the human voice is a crucial aspect of social cognition. Currently, very little known about neural correlates nonverbal emotional vocalizations processing. We used electrophysiological measures examine processing versus neutral vocalizations. Participants listened angry, happy, and vocalizations, as well monkey voices, which served response target. Angry sounds were processed differently than happy ones starting at 50 ms, whereas both vocal associated...
The aim of this study was to examine symptoms posttraumatic stress disorder (PTSD), depression, and anxiety among junior high school students in worst-hit areas 3 years after the Wenchuan earthquake. Analyses were carried out on 373 377 enrolled. In addition obtaining demographic characteristics, Impact Event Scale–Revised, Zung Self-rating Depression Scale, Anxiety an Earthquake exposure screening scale administered. It found that 29.6%, 44.8%, 37.6% participants reported clinical PTSD,...
Purposes Since a considerable number of health care workers (HCWs) were sent to Wuhan aid COVID-19 control during the epidemic, non-frontline HCWs who stayed in local hospitals had work overload provide daily services for other issues, which makes them more vulnerable experience fatigue. Self-efficacy is suggested as protective factor Nonetheless, less known regarding underlying mechanisms. This research aimed explore prevalence fatigue among pandemic, investigate mediating effect...
Alcoholic liver disease (ALD) is associated with hepatic inflammatory activation and iron overload. The receptor for advanced glycation end products (RAGE) an important metabolic mediator during the development of ALD. aim this study was to determine effect RAGE on homeostasis in We found increased circulating transferrin, hepcidin ferritin ALD patients positively correlated level. knockout (RAGE-/-) wild-type mice were subjected chronic alcoholic feeding 6 weeks induce ALD, inhibitor,...
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic and continues to rise in worldwide. Limonin a triterpenoid compound widely found fruits citrus plants with wide range pharmacological effects, including anti-cancer, anti-inflammation, anti-viral, anti-oxidation protection properties. However, potential molecular mechanism limonin on NAFLD zebrafish remains unknown. In this study, larvae were exposed thioacetamide establish an model treated for 72 h simultaneously....
Hepatic steatosis is the early stage of alcoholic liver disease (ALD), may progress to steatohepatitis, fibrosis even cirrhosis. Polydatin, primary active component Polygonum cuspidatum Sieb. et Zucc, has been recognized possess hepatoprotective and anti-inflammatory properties. To investigate whether polydatin alleviates ethanol induced injury elucidate underlying molecular mechanisms, zebrafish larvae at 4 days post-fertilization (dpf) were exposed 350 mmol/L for 32 h, then treated with 48...
Introduction: One year after the Coronavirus disease 2019 (COVID-19) outbreak, China has made substantial progress in prevention and control of pandemic, while epidemic situation remains grim since virus may easily survive with falling temperature winter. The present study aimed to compare prevalence associated factors anxiety between high-risk low-risk nurses 1 COVID-19 examine association resilience its underlying mechanisms. Method: Connor-Davidson Resilience scale, Perceived Social...
As the traditional Chinese herbal formula, Xiaoyaosan and its modified formula have been described in many previous studies with definite anti-depressive effects, but underlying mechanism remains mystery. Previous work our lab has demonstrated that depression induced by chronic stress could generate brain blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) signals disorder, accompanied impairment of hippocampal neuronal plasticity, decrease brain-derived...
Medical staff were battling against coronavirus disease 2019 (COVID-19) at the expense of their physical and mental health, particularly risk for posttraumatic stress disorder (PTSD). In this case, intervening PTSD medical preparing them future outbreaks are important. Previous studies showed that perceived was related to development PTSD. Hence, in study, association between perception symptoms COVID-19 potential links explored. Three hundred four staff's exposure patients, working during...
This paper describes a practical, enantio- and diastereoselective Mannich reaction between chiral Ni(II) complex of glycine 1 α-amino sulfones 2, involving the creation carbon−carbon bond two stereogenic centers in single operation; it represents an attractive route to synthesis α,β-diamino acids.
The primary goals of this study, were to identify the posttraumatic growth (PTG) level accidentally injured Chinese patients shortly after an accident occurred and determine whether cognitive processing, self-disclosure, psychosocial resources predicted PTG. A total 232 recruited from two public hospitals in Shanghai within first three months accidental injury. Patients completed self-report questionnaires assess severity injury, resources, reported a mid-low PTG (M = 50.38, SD 18.12) short...