A5003437612- Antibiotic Use and Resistance
- Urinary Tract Infections Management
- Patient Satisfaction in Healthcare
- Geriatric Care and Nursing Homes
- Chronic Kidney Disease and Diabetes
- Chronic Disease Management Strategies
- Computational Drug Discovery Methods
- Pneumonia and Respiratory Infections
- Global Health Care Issues
- Health Promotion and Cardiovascular Prevention
- COVID-19 Impact on Reproduction
- Global Maternal and Child Health
- Urinary Bladder and Prostate Research
- Health Systems, Economic Evaluations, Quality of Life
- Statistical Methods in Clinical Trials
- Healthcare Systems and Technology
- Renal and Vascular Pathologies
- Bacterial Identification and Susceptibility Testing
- Nosocomial Infections in ICU
- Pelvic floor disorders treatments
- Frailty in Older Adults
- Primary Care and Health Outcomes
- Mobile Health and mHealth Applications
- Pharmacovigilance and Adverse Drug Reactions
- Telemedicine and Telehealth Implementation
University of Limerick
2024-2025
University College Dublin
2022-2024
University of North Carolina at Chapel Hill
2019-2023
National University of Ireland
2019-2020
Cecil College
2020
Ollscoil na Gaillimhe – University of Galway
2015-2019
Abstract Background Using the Irish Longitudinal Study on Ageing (TILDA), we evaluated prevalence and distribution of chronic kidney disease (CKD), its determinants in order to identify risk groups for population health planning Ireland. Methods Data were analysed from Wave 1 (2009-2011) TILDA, a national cohort participants aged 50+ who had both plasma creatinine cystatin C measured at baseline. Kidney function was estimated using 2012 2021 CKD-EPI equations. CKD defined as eGFR < 60...
Identifying the unintended effects of drugs (side effects) is a very important issue in pharmacological studies. The laboratory verification associations between and side requires costly, time-intensive research. Thus, an approach to predicting drug based on known effects, using computational model, highly desirable. To provide such we used openly available data resources model as bipartite graph. drug-drug network constructed word2vec where edges represent semantic similarity them. We...
Current antimicrobial prescribing guidelines indicate that male and female patients with urinary tract infections (UTIs) should be treated same antimicrobials but for different durations. The aim of this study was to explore the differences in reconsultations UTI both males females. A total 2557 adult suspected participating Supporting Improvement Management Prescribing infection (SIMPle) from 30 general practices were analyzed. An prescribed significantly more often females (77%) than...
Background The 2016 point prevalence survey (PPS) of healthcare-associated infections (HAI) and antimicrobial use (AMU) in Irish long-term care facilities (LTCF) (HALT) showed a 9.8% AMU 4.4% HAI prevalence, based on aggregated data analysis. Aim Our aim was to identify institutional resident risk factors HAI. Methods HALT gathered information using questionnaires, for residents who met the surveillance definition active and/or AMU, limiting analysis level. In January 2017, we requested...
Identify changes in the prevalence and antimicrobial resistance patterns of potentially pathogenic bacteria urine cultures during a 2-year stewardship intervention program nursing homes (NHs).Before-and-after study.The study included 27 NHs North Carolina.We audited all ordered before an intervention. Analyses compared culture rates, positive pathogen patterns.Of 6,718 total collected, 68% were for bacteria. During intervention, significant reductions rates observed (P = .014). Most...
Hypertension is highly prevalent in chronic kidney disease (CKD), posing a significant but modifiable risk for adverse clinical outcomes. This study explored the prevalence, awareness, treatment, and control of hypertension older Irish adults with CKD.
Mobile phones offer new opportunities to efficiently and interactively collect real-time data from patients with acute illnesses, such as urinary tract infections (UTIs). One of the main benefits using mobile collection methods is automated upload, which can reduce chance loss, an issue when other paper-based surveys.The aim was explore differences in collecting UTI text messaging, a phone app (UTI diary), online survey. This paper provides lessons learned integrating into randomized...
Background Long-term care facilities (LTCFs) are important locations of antimicrobial consumption. Of particular concern is inappropriate prescribing prophylactic antimicrobials. Aim We aimed to explore factors related prophylaxis in LTCFs Ireland. Methods The point prevalence surveys Healthcare-Associated Infections Long-Term Care Facilities (HALT) were performed Ireland May 2013 and 2016. Data collected on facility (type stewardship initiatives) resident characteristics (age, sex,...
A European placebo-controlled trial of antibiotic treatment for lower respiratory tract infection (LRTI) conducted in 16 primary care practices networks recruited participants between November 2007 and April 2010, found adverse events (AEs) occurred more often patients prescribed amoxicillin compared to placebo. This secondary analysis explores the causal relationship estimates specific AEs (diarrhoea, nausea, rash) due LRTI, if any subgroup is at increased risk or a AE. total 2061 were...
Inappropriate antimicrobial prescribing contributes to the global spread of resistance. The pending weekend with changed availability general practitioners (GP) and increased patient concern may increase intention prescribe antimicrobials. aim this study is analyse variation in between weekdays Irish practice. All data over a 15 month period was obtained from 30 practices participating Supporting Improvement Management Prescribing for urinary tract infection (SIMPle) study. Antimicrobials...
Predicting the onset time of adverse drug events can substantially lessen negative impact on prognosis cancer patients who are often subject aggressive and highly toxic treatment regimens. However, laboratory verification each patient case to study mechanics requires costly, time-intensive research. Thus, alleviate efforts required tackle this problem, using computational models is desirable. To provide a suite such applicable models, we used openly available event data resources called...
Information on the readiness of Irish general practice to participate in structured chronic disease management (CDM) care is limited. This study explores logistic, staffing, and organizational preparedness do so, stratified by their size, location, training status; implementation challenges were also explored. An anonymous, paper-based random survey was performed. A chi-square test applied compare practices location (urban/rural), post-graduate status (with/without), numbers GMS patient...