- Biosensors and Analytical Detection
- Microfluidic and Capillary Electrophoresis Applications
- Advanced biosensing and bioanalysis techniques
- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced Biosensing Techniques and Applications
- Semiconductor materials and devices
- 3D Printing in Biomedical Research
- Integrated Circuits and Semiconductor Failure Analysis
- Advancements in Semiconductor Devices and Circuit Design
- Microfluidic and Bio-sensing Technologies
- Bacteriophages and microbial interactions
- SARS-CoV-2 detection and testing
- Additive Manufacturing and 3D Printing Technologies
- Molecular Biology Techniques and Applications
- Gene expression and cancer classification
- Cell Image Analysis Techniques
- DNA and Nucleic Acid Chemistry
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- ZnO doping and properties
- Cellular Mechanics and Interactions
- Genetics, Bioinformatics, and Biomedical Research
- Transition Metal Oxide Nanomaterials
- Nanofabrication and Lithography Techniques
- Bacterial Identification and Susceptibility Testing
Korea Polytechnic University
2018-2024
Soonchunhyang University
2024
National NanoFab Center
2016-2023
Kongju National University
2023
Korea University of Technology and Education
2022-2023
Hankyong National University
2010-2021
Daejeon University
2015-2020
University of Washington
2017-2019
Seattle University
2019
Korea Advanced Institute of Science and Technology
2012-2018
The advantageous physiochemical properties of poly(dimethylsiloxane) (PDMS) have made it an extremely useful material for prototyping in various technological, scientific, and clinical areas. However, PDMS molding is a manual procedure requires tedious assembly steps, especially 3D designs, thereby limiting its access usability. On the other hand, automated digital manufacturing processes such as stereolithography (SL) enable true design fabrication. Here formulation, characterization, SL...
Stereolithography (SL) is emerging as an attractive alternative to soft lithography for fabricating microfluidic devices due its low cost and high design efficiency. Low molecular weight poly(ethylene glycol)diacrylate (MW = 258) (PEG-DA-258) has been used SL 3D-printing of biocompatible microdevices at submillimeter resolution. However, resins that simultaneously feature transparency, biocompatibility, resolution are still lacking. It found photosensitizer isopropyl thioxanthone can, in a...
In this study, we developed lateral flow assay (LFA) biosensors for the detection of hepatitis B surface antigens using well-controlled gold nanoparticles (AuNPs). To enhance colorimetric signals, a seeded growth method was used preparation size-controlled AuNPs with narrow size distribution. Different sizes in range 342-137.8 nm were conjugated antibodies and then optimized efficient LFA biosensors. The conjugation stability investigated by UV-vis spectroscopy AuNP dispersion at various pH...
A novel trace lead ion (Pb(2+)) detection platform by combining a microfluidic sample pretreatment device with DNA aptamer linked photoluminescent graphene oxide quantum dot (GOQD) sensor was proposed. The multilayered microdevice included microchamber which packed cation exchange resins for preconcentrating metal ions. loading and recovery were automatically actuated peristaltic polydimethylsiloxane micropump flow rate of 84 μL/min. Effects the actuation time, concentration, pH, volumes...
We have developed a sequential stereolithographic co-printing process using two different resins for fabricating porous barriers in microfluidic devices. 3D-printed channels with resin made of poly(ethylene glycol) diacrylate (MW = 258) (PEG-DA-258), UV photoinitiator, and sensitizer. The were created within the microchannels either PEG-DA 575) (PEG-DA-575) or 40% (
We demonstrated a stereolithographically 3D-printed chip for the straightforward injection of hydrogel barriers in microchannels and facile measurement molecular diffusivities through these hydrogels.
The antimicrobial resistance of 122 Shigella sonnei isolates obtained in Korea during the period 1991-2000 was characterized. These were highly resistant to traditional antibiotics such as trimethoprim (100 %), streptomycin sulfamethoxazole (94 tetracycline (93 %) and nalidixic acid (90 %). All S. carried Tn7 their chromosomes. 8.4 kb non-transferable (R) plasmid carrying tetA, strA-strB sul1 found 93 % isolates. Resistance first appeared a isolate 1997, then all from 1998 1999. commonly...
Sensitive and accurate capture, enrichment, identification of drug-resistant bacteria on human skin are important for early-stage diagnosis treatment patients. Herein, we constructed a three-dimensional hierarchically structured polyaniline nanoweb (3D HPN) to enrich, detect on-site by rubbing infected skins. These unique hierarchical nanostructures enhance capture efficiency help severely deform the surface entrapped them. Therefore, 3D HPN significantly contributes effective reliable...
Spherical 3D graphite microballs (3D GMs) and their nanohybrids GM–Fe3O4 nanoparticles) were synthesized by using a microfluidic droplet generator thermal evaporation-induced capillary compression method. Using the nanoparticle as support for polymerization, GM–polypyrrole composites produced with unique core–shell structure.
The digital nucleic acid assay is a precise, sensitive, and reproducible method for determining the presence of individual target molecules separated in designated partitions; thus, this technique can be used detection. Here, we propose multifunctional micropattern array capable isolating into partitions simultaneous on-site cell lysis to achieve direct DNA extraction digitized quantification thereof. fabricated by deposition copolymer film, poly(2-dimethylaminomethyl styrene-co-hydroxyethyl...