A5101744403- Growth Hormone and Insulin-like Growth Factors
- Antifungal resistance and susceptibility
- Microscopic Colitis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Pluripotent Stem Cells Research
- Cancer-related molecular mechanisms research
- Lung Cancer Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Long-Term Effects of COVID-19
- Asthma and respiratory diseases
- Radiation Dose and Imaging
- Mobile Health and mHealth Applications
- Pharmacovigilance and Adverse Drug Reactions
- Health Literacy and Information Accessibility
- Patient Safety and Medication Errors
- COVID-19 and Mental Health
- Cardiac Health and Mental Health
- Colorectal Cancer Screening and Detection
- RNA Research and Splicing
- Cardiac Arrhythmias and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Cell Adhesion Molecules Research
- COVID-19 Clinical Research Studies
- Esophageal and GI Pathology
ACT Government
2024
Canberra Hospital
2024
Harrogate District Hospital
2022
Albert Einstein College of Medicine
2020
Massachusetts Institute of Technology
2020
National Institutes of Health
2019
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2019
Washington University in St. Louis
2015
San Francisco VA Medical Center
2014
University of the Pacific
2014
Phthalates are commonly used in plastic products daily life. The endocrine-disrupting effects of phthalates have been widely reported. Accumulating evidence from human cohorts and lab animals indicate exposure to might impair neurodevelopment. However, the direct causal relationship mechanism between with neurodevelopment neurotoxicity not firmly established. We found that (i.e. DBP, DINP, BBP) disrupted expression estrogen receptors (esr1, esr2a, esr2b), impaired neurogenesis brain...
Raised blood pressure or hypertension is by far the leading risk factor for preventable deaths in Australia, contributing to over 25 000 annually (Supporting Information, figure 1 and 2),1-3 mainly due stroke, heart disease, kidney failure, atrial fibrillation dementia.3, 4 The reduction of less than 140/90 mmHg only achieved 32% people with control rates have stagnated a decade 3).5, 6 As our compare poorly other high income countries (eg, 68% Canada),5-7 we published call-to-action...
Recombinant human growth hormone (GH) is commonly used to treat short stature in children. However, GH treatment has limited efficacy, particularly severe, non-GH-deficient conditions such as chondrodysplasias, and potential off-target effects. Because results from decreased plate chondrogenesis, we developed a cartilage-targeting single-chain antibody fragment (CaAb) aiming deliver therapeutic molecules the plate, thereby increasing efficacy while minimizing adverse effects on other...
Flecainide is a Vaughan Williams class 1c antiarrhythmic used to treat supraventricular and ventricular arrhythmias. It has been described as rare cause for increased pacemaker capture thresholds. We describe report of patient, in her early 80s, presenting with tachy-brady syndrome on background permanent atrial fibrillation. She was treated metoprolol flecainide by private cardiologist. Permanent right chamber pacing recommended slow heart rate. At insertion single pacemaker, she noted have...
Few studies have explored the impact of using different methods for obtaining accurate medication histories on safety. This study was conducted to compare accuracy and clinical pharmacist obtained by electronic medical record review (EMRR) alone with those direct interviews combined EMRR.This 18-week prospective included patients who were admitted Inpatient Medicine Service at institution had a pharmacist-conducted reconciliation EMRR within 48 hours hospital admission. A chart performed...
Staphylococcus aureus subcapsular splenic abscess and associated empyema in the setting of tocilizumab therapy: A case report Key Clinical MessageWe a after recent commencement tocilizumab, masquerading as musculoskeletal pain.This highlights importance considering unusual underlying infections patients on tocilizumab.
Key Clinical Message We report a case of Staphylococcus aureus subcapsular splenic abscess and associated empyema after recent commencement tocilizumab, masquerading as musculoskeletal pain. This highlights the importance considering unusual underlying infections in patients on tocilizumab.
Recombinant human growth hormone (GH) is commonly used to treat short stature in children. However, GH treatment has limited efficacy particularly severe, non-GH deficient conditions such as chondrodysplasias, and potential off-target effects. Because results from decreased plate chondrogenesis, we previously developed a cartilage-targeting single-chain antibody fragment (CaAb) (1), aiming deliver therapeutic molecules the plate, thereby increasing while minimizing adverse effects on other...
<h3>Introduction</h3> Colonoscopy is increasingly being performed in the very elderly patients with some data suggesting this safe and efficacious<sup>1</sup>. Here we assess safety outcomes for these an NHS district general hospital. <h3>Method</h3> In retrospective study, all above age of 90 attending a colonoscopy were identified through electronic database. Reports retrieved medical records reviewed. <h3>Results</h3> Between Jan 2016 June 2021, 142 mean 91 (90-98 years) to have undergone...