A5063393755- Pomegranate: compositions and health benefits
- Drug Transport and Resistance Mechanisms
- Vitamin D Research Studies
- Psoriasis: Treatment and Pathogenesis
- Phytochemicals and Medicinal Plants
- Immune Response and Inflammation
- Cynara cardunculus studies
- Dental Health and Care Utilization
- Essential Oils and Antimicrobial Activity
- Pharmacology and Obesity Treatment
- Pregnancy and preeclampsia studies
- Romani and Gypsy Studies
- Therapeutic Uses of Natural Elements
- Smoking Behavior and Cessation
- Body Composition Measurement Techniques
- Vitamin C and Antioxidants Research
- Pediatric Hepatobiliary Diseases and Treatments
- Dental Research and COVID-19
- Hibiscus Plant Research Studies
- Gestational Diabetes Research and Management
- Obesity and Health Practices
- Bone health and osteoporosis research
- Liver Disease Diagnosis and Treatment
- Thermoregulation and physiological responses
- Sesame and Sesamin Research
University of Banja Luka
2013-2025
Public Health Institute of the Republic of Srpska
2017-2022
Institute for Plant Protection and Environment
2020
University of Belgrade
2020
ORCID
2015
Background: Type 2 diabetes mellitus (T2DM) is commonly associated with hyperglycemia, dyslipidemia, oxidative stress and inflammation which are well known cardiovascular risk factors. Pomegranate peel polyphenols have a proven hypolipemic, antioxidant anti-inflammatory activity. However, there lack of clinical studies that would confirm its effects in diabetic patients. The potential pomegranate extract (PoPEx) to counteract T2DM patients was investigated. For this purpose, randomized,...
Pomegranate peel contains high levels of various phytochemicals. We evaluated the effects pomegranate extract (PoPEx) consumption on plasma lipid profile, fatty acids (FA) level and blood pressure (BP) in patients with diabetes mellitus type 2 (DMT2). Thirty-seven subjects were recruited this double blind, placebo controlled randomized trial. The study group (n = 19) received over 8 week’s capsules containing PoPEx twice a daily, while placebo. Treatment induced significant lowering both...
The search for effective coronavirus disease (COVID-19) therapy has attracted a great deal of scientific interest due to its unprecedented health care system overload worldwide. We have carried out study investigate the in silico effects most abundant pomegranate peel extract constituents on multi-step process serious acute respiratory syndrome 2 (SARS-CoV-2) internalization host cells. Binding affinities and interactions ellagic acid, gallic punicalagin punicalin were studied four selected...
Background. Oxidative stress and inflammation are closely related pathophysiological processes, both occurring in type 2 diabetes mellitus (T2DM). In addition to the standard treatment of T2DM, a potential strategy has been focused on use bile acids (BAs) as an additional treatment. Ursodeoxycholic acid (UDCA), first BA used humans, improves glucose lipid metabolism attenuates oxidative stress. The aim this study was evaluate metabolic, anti-inflammatory, antioxidative effects UDCA patients...
Abstract Bacterial lipopolysaccharide (LPS) induces general inflammation, by activating pathways involving cytokine production, blood coagulation, complement system activation, and acute phase protein release. The key cellular players are leukocytes endothelial cells, that lead to tissue injury organ failure. aim of this study was explore the anti-inflammatory, antioxidant, cytoprotective properties two bile acids, ursodeoxycholic acid (UDCA) chenodeoxycholic (CDCA) in LPS-induced...
Introduction This study aimed to investigate the anti-inflammatory, antioxidant, and anti-apoptotic properties of ursodeoxycholic (UDCA) chenodeoxycholic (CDCA) bile acids in a rat model endotoxin (lipopolysaccharide, LPS)-induced acute lung injury (ALI). Methods The included six groups Wistar rats exposed different pretreatments. control were pretreated with propylene glycol, solvent for acids, while other received UDCA or CDCA 10 days. On 10th day, an injection was given evaluate impact...
Psoriasis is an autoimmune and inflammatory skin disease. Psoriatic patients express higher levels of plasma homocysteine (Hcy) concentration pro-inflammatory mediators than healthy people; this frequently associated with vitamin D deficiency. The aim clinical study was to investigate the effects high doses supplementation on parameters Hcy metabolism cytokines in sera psoriatic patients. This prospective conducted 40 who had All received 5000 IU/day for three months. Clinical biochemical...
Abstract Bacterial lipopolysaccharide (LPS) induces general inflammation, by activating pathways involving cytokine production, blood coagulation, complement system activation, and acute phase protein release. The key cellular players are leukocytes endothelial cells, that lead to tissue injury organ failure. aim of this study was explore the anti-inflammatory, antioxidant, cytoprotective properties two bile acids, ursodeoxycholic acid (UDCA) chenodeoxycholic (CDCA) in LPS-induced...
<b>Background/Aim:</b> Polyphenol compounds obtained from pomegranate have beneficial pharmacological activities in the treatment of diabetes mellitus type 2 (DMT2). Most DMT2 patients are overweight or obese and obesity by itself is very much related to insulin resistance abnormalities secretion. This clinical study aimed evaluate peel extract (PoPEx) activity on anthropometric parameters body composition with DMT2. <b>Methods:</b> Sixty continuous metformin therapy were involved this...
Background and aimsBody composition in childhood is not only a marker of the prevalence obesity, but it can also be used to assess associated metabolic complications. Bioelectrical impedance analysis (BIA) shows promise as an easy use, rapid, non-invasive tool evaluate body composition. The objectives this study were to: (a) develop BIA prediction equations estimate total water (TBW) fat-free mass (FFM) European children early adolescents validate with deuterium dilution reference technique...
The aim of this study was to explore the health status and needs Roma women in two biggest communities Republic Srpska, Bosnia & Herzegovina. Data presented work were collected through assessment 183 adult women, which part improvement program. Logistic regression used assess degree absence medical supervision by a provider related sociodemographic characteristics women. majority had no schooling, 62.8 % 88.5% unemployed, while 93.9% insurance, card, registered with Family Medicine Doctor....
Introduction. Children with hearing impairment do not understand speech without specific instructions and cannot meet daily life requirements. have higher DMFT index poorer oral hygiene than healthy children of the same age. The aim this study was to determine health status prevalence dental caries in attending Center for Education Rehabilitation Speech Hearing Banjaluka. Material Methods. conducted as a cross-sectional it included 66 both genders, age 3 18 years, deciduous, mixed permanent...
: The aim of this study was to determine the role physicians in intensive intervention and education regarding smoking cessation patients undergoing elective surgery under general anaesthesia.
Background: Within the goals of Protocol on Water and Health, Bosnia Herzegovina has set objective improving Water, Sanitation, Hygiene (WASH) in primary schools. The baseline WASH survey schools is planned as first activity its achievement. aim research to examine state Republic Srpska. Methods Objectives: This was conducted from September 2019 March 2020 We evaluated condition 66 Two instruments were employed for data collection: a questionnaire administered school administrative staff...
Introduction. Dental status in people with special needs is generally non satisfactory. Children have difficulties maintaining oral hygiene, they require conditions for dental care and because of previous negative experience often show emotional vulnerability. Development diseases these subjects the consequence insufficient knowledge about causes diseases, poor eating habits, low level hygiene inadequate number visits to dentist. The aim this study was determine prevalence caries children...
Introduction/Objective. Not only do pre-pregnancy overweight or obesity increase the risk of adverse maternal and perinatal outcomes but they also lead to development gestational diabetes mellitus. The objective this study was estimate prevalence in Republic Srpska investigate its association with hyperglycemia Methods. A cross-sectional carried out during period from February October 2012 among 555 pregnant women 24 28 weeks. criterion for exclusion sample previously diagnosed type 1 2...
Background/Aim: Psoriasis is a chronic inflammatory skin disease that associated with higher prevalence of cardiovascular (CV) risk factors. The effect vitamin D on bone health has been long known, but its extraskeletal role especially in and disease, the subject recent research. This study aimed to assess influence high-dose supplementation Area Severity Index (PASI) score lipid profile patients psoriasis. Methods: included 20 adult plaque They received capsules daily dose 5,000 IU over 12...