A5063573163- Cannabis and Cannabinoid Research
- Sleep and related disorders
- Sleep and Wakefulness Research
- Muscle metabolism and nutrition
- Sleep and Work-Related Fatigue
- Obesity, Physical Activity, Diet
- Forensic Toxicology and Drug Analysis
- Thermoregulation and physiological responses
- Coffee research and impacts
- Diet and metabolism studies
- Sports Performance and Training
- Cardiovascular and exercise physiology
- Nutritional Studies and Diet
- Behavioral Health and Interventions
- Traumatic Brain Injury Research
- Alcohol Consumption and Health Effects
- Exercise and Physiological Responses
- Substance Abuse Treatment and Outcomes
- Traffic and Road Safety
- Prenatal Substance Exposure Effects
- Eating Disorders and Behaviors
- Traumatic Brain Injury and Neurovascular Disturbances
- Obstructive Sleep Apnea Research
- Sensory Analysis and Statistical Methods
- Older Adults Driving Studies
The University of Sydney
2019-2025
Woolcock Institute of Medical Research
2020-2024
Macquarie University
2023
Griffith University
2016-2022
Baker Heart and Diabetes Institute
2015
The University of Texas at Austin
2014
Background: Cannabidiol (CBD), a major cannabinoid of Cannabis sativa, is widely consumed in prescription and non-prescription products. While CBD generally considered ‘non-intoxicating’, its effects on safety-sensitive tasks are still under scrutiny. Aim: We investigated the driving performance. Methods: Healthy adults ( n = 17) completed four treatment sessions involving oral administration placebo, or 15, 300 1500 mg randomised, double-blind, crossover design. Simulated performance was...
Cannabidiol (CBD) has demonstrated anti-inflammatory, analgesic, anxiolytic and neuroprotective effects that have the potential to benefit athletes. This pilot study investigated of acute, oral CBD treatment on physiological psychological responses aerobic exercise determine its practical utility within sporting context.On two occasions, nine endurance-trained males (mean ± SD V̇O2max: 57.4 4.0 mL·min-1·kg-1) ran for 60 min at a fixed intensity (70% V̇O2max) (RUN 1) before completing an...
Background Medical cannabis use is increasingly common in Australia. Patients and physicians need to be aware of the important implications that such may have for driving. Objective The aim this article briefly review scientific evidence regarding driving impairment discuss current legal issues affecting patients, as well update on relevant best guidance offer their patients. Discussion Delta-9-tetrahydrocannabinol (THC) impairs performance can increase crash risk. These effects are more...
Several single-nucleotide variants (SNVs) in low-density lipoprotein receptor-related protein 6 (Lrp6) cause neural tube defects (NTDs) mice. We therefore examined LRP6 192 unrelated infants from California with the NTD, spina bifida, and found four heterozygous missense SNVs, three of which were predicted to be deleterious, among NTD cases not 190 ethnically matched nonmalformed controls. Parents siblings could tested because study design. Like Crooked tail Ringleschwanz mouse variants,...
Abstract Introduction In January 2020, the government of Australian Capital Territory (ACT) decriminalised possession and cultivation cannabis for personal use. This study explored driving‐related attitudes, beliefs behaviours ACT residents who are legally cultivating consuming cannabis. Methods A two‐part cross‐sectional was conducted. Part‐1: Cannabis users residing in were invited to complete an online survey. Part‐2: Survey respondents reported ‘currently growing’ submit a sample their...
The Australian Capital Territory (ACT), a region that includes Australia's capital, Canberra, decriminalised small-scale cannabis cultivation and possession in January 2020. Here, we examined use behaviours, experiences attitudes of current past ACT cultivators. residents (n = 311) who currently cultivate or have previously cultivated completed cross-sectional online survey ('CAN-ACT') provided home-grown for phytocannabinoid analysis (optional). Reasons included preference to self-supply,...
The aim of this study was to determine the influence training volume alterations on diversity and composition gut microbiome in a free-living cohort middle-distance runners. Fourteen highly-trained runners (n = 8 men; V˙O2peak 70.1 ± 4.3 ml·kg·min-1; n 6 women, V˙O2peak: 59.0 3.2 ml·kg·min-1) completed three weeks normal (NormTr), high-volume (HVolTr; 10, 20 30% increase during each successive week from NormTr), one-week taper (TaperTr; 55% exponential reduction HVolTr three). Faecal samples...
Australian pharmacists currently dispense a wide range of prescription-only cannabis-based medicines. Recent regulatory changes will expand the role pharmacists, allowing certain low-dose cannabidiol products to be supplied without prescription in pharmacies. This harmonises Australia with many other countries where are readily available consumers.To examine pharmacists' experience, knowledge and attitudes towards medicinal cannabis their preparedness supply over-the-counter products.We...
Abstract Background Exercise is known to improve health. However, it can be unpleasant, often inducing negative feelings, or ‘affect’. Cannabidiol (CBD), a non-intoxicating constituent of the cannabis plant, has been reported enhance subjective experience exercise; specifically, in trained individuals performing fixed-intensity endurance activity. Here, we investigated effects CBD on responses exercise under more ecologically valid conditions; namely, recreationally active self-paced Methods...
Medicinal cannabis (MC) products have been available on prescription in Australia for around six years. General practitioners (GPs) are at the forefront of MC prescribing and recent years seen substantial increases numbers. This study examined current knowledge, experiences, attitudes Australian GPs MC. We also compared our findings to those an earlier 2017 investigation.
A growing number of clinical trials (CTs) are investigating the therapeutic potential cannabidiol (CBD), a non-intoxicating phytocannabinoid found in Cannabis sativa. These CTs often use crossover experimental designs requiring 'washout' (clearance) periods. However, length time CBD persists plasma (its 'window detection') is unclear and could be significant. Indeed, structurally related phytocannabinoid, Δ9 -tetrahydrocannabinol (THC), has long window detection plasma. We investigated...
Objective: Fatal vision goggles (FVGs) are image-distorting equipment used within driver education programs to simulate alcohol-related impairment. However, there is no empirical evidence comparing the behavioral effects associated with wearing FVGs alcohol intoxication. The purpose of this study was determine validity in producing impairment simulated driving.Methods: Twenty-two healthy males (age: 23 ± 3 years, mean SD) participated a placebo-controlled crossover design involving 4...