A5080289942- Exercise and Physiological Responses
- Gut microbiota and health
- Muscle metabolism and nutrition
- Diet and metabolism studies
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Sports Performance and Training
- Probiotics and Fermented Foods
- Nutritional Studies and Diet
- Cardiovascular and exercise physiology
- Respiratory viral infections research
- Pediatric health and respiratory diseases
- Stress Responses and Cortisol
- Dermatology and Skin Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Molecular Biology Techniques and Applications
- Heat shock proteins research
- Sports injuries and prevention
- Cardiovascular Effects of Exercise
- High Altitude and Hypoxia
- Advanced biosensing and bioanalysis techniques
- Tryptophan and brain disorders
- Heart Rate Variability and Autonomic Control
- Pneumonia and Respiratory Infections
- Chronic Obstructive Pulmonary Disease (COPD) Research
Griffith University
2015-2024
The University of Queensland
2024
Westmead Institute for Medical Research
2024
University of Münster
2024
University of Central Florida
2016-2023
Icahn School of Medicine at Mount Sinai
2023
Menzies School of Health Research
2015-2019
ENT and Allergy
2017
National Heart Foundation of Australia
2014
Australian Sports Commission
2005-2010
To evaluate the ability of a probiotic Lactobacillus fermentum VRI-003 (PCC) to enhance mucosal immune system elite athletes.A double-blind, placebo-controlled, crossover trial was conducted over 4-month period winter training. PARTICIPANTS; 20 healthy male distance runners.PCC given at daily dose 1.26 x 10(10) as freeze-dried powder in gelatin capsules. Placebo capsules contained an inert excipient.Treadmill performance (monthly), and systemic immunity training (daily) illness were...
We determined the effects of varying daily carbohydrate intake by providing or withholding during training on endurance performance, whole body rates substrate oxidation, and selected mitochondrial enzymes. Sixteen endurance-trained cyclists triathletes were pair matched randomly allocated to either a high-carbohydrate group (High group; n = 8) an energy-matched low-carbohydrate (Low for 28 days. Immediately before study commencement final 5 days, subjects undertook 5-day test block in which...
Objective: To characterize the etiology of upper respiratory symptoms in elite athletes presenting to a sports physician for treatment. Design: Prospective clinical and laboratory investigations. Setting: Sports medicine clinic. Participants: Seventy elite-level athletes. Main Outcome Measurements: Physician-recorded diagnosis; health/training questionnaires; investigations pathogens, white blood cell differential counts, immune parameters. Results: Physicians characterized 89% presentations...
Abstract We critically review potential involvement of trimethylamine N -oxide (TMAO) as a link between diet, the gut microbiota and CVD. Generated primarily from dietary choline carnitine by bacteria hepatic flavin-containing mono-oxygenase (FMO) activity, TMAO could promote cardiometabolic disease when chronically elevated. However, control circulating is poorly understood, age, body mass, sex hormones, renal clearance, FMO3 expression genetic background may explain little 25 % variance....
Cannabidiol (CBD) has demonstrated anti-inflammatory, analgesic, anxiolytic and neuroprotective effects that have the potential to benefit athletes. This pilot study investigated of acute, oral CBD treatment on physiological psychological responses aerobic exercise determine its practical utility within sporting context.On two occasions, nine endurance-trained males (mean ± SD V̇O2max: 57.4 4.0 mL·min-1·kg-1) ran for 60 min at a fixed intensity (70% V̇O2max) (RUN 1) before completing an...
Viral respiratory tract infections are frequently complicated by secondary bacterial infections. This study aimed to use machine learning predict the risk of superinfection in SARS-CoV-2-positive individuals.
Background: Fatigue and impaired performance in athletes is well recognised has been loosely linked to “overtraining”. Reduced concentration of IgA the saliva increased shedding Epstein Barr virus (EBV) have associated with intense training elite athletes. Objective: To determine whether presenting fatigue had an immune defect relevant defective containment EBV infection, a probiotic preparation ( Lactobacillus acidophilus ) shown enhance mucosal immunity animal models could reverse any...
Purpose: To characterize differences in cytokine responses to exercise of different intensities and durations between healthy illness-prone runners. Methods: Trained distance runners were classified as (no more than two episodes upper-respiratory symptoms per year; N = 10) or (four 8) completed three treadmill tests: SHORT (30 min, 65% V˙O2max), LONG (60 INTENSE (6 × 3 90% V˙O2max). Blood samples collected pre-, post-, 1 h, 10 24 h after exercise, interleukin (IL)-2, IL-4, IL-6, IL-8, IL-10,...
Introduction: Unique gut microbial colonisation patterns are associated with the onset of allergic disease in infants; however, there is insufficient evidence to determine if aberrant composition persist adult rhinitis (AR) sufferers. Objective: To compare microbiome between AR sufferers and controls. Methods: Gut stool samples was compared 57 (39.06 ± 13.29 years) 23 controls (CG; 36.55 10.51 via next-generation sequencing V3–V4 hypervariable regions 16S rRNA gene. Taxonomic classification...
Abstract Cold water immersion and compression garments are now popular strategies for post‐exercise recovery. However, little information exists on the effectiveness of these to minimize muscle damage, or any impact they may have biomarker clearance after team sport competition. The main aim this study was investigate time course damage markers inflammatory cytokines during basketball tournament play. We also wished examine if cold recovery ameliorate post‐game increases biomarkers, compared...
To investigate relationships between training mileage and intensity, the type, incidence, severity, duration of respiratory illness in distance runners, impact on submaximal maximal running performance.A longitudinal observational study runners with serial monitoring loads clinical patterns illness.A 4-month winter period Southern Hemisphere.A total 20 highly trained (elite) male middle-distance competing at national international levels.Training was quantified by (km), intensity (scale,...
The uptake and distribution of CO throughout the circulatory system during two different methods rebreathing (2 min 'Schmidt' 40 'Burge' methods) were determined in nine healthy volunteers. Specifically, impact (i) differences mixing time (t(mix)), (ii) diffusion to myoglobin (Mb) (iii) wash-out was assessed on calculated haemoglobin mass (Hb(mass)). Arterial (a), muscle venous (vm) capillary samples (c) obtained simultaneously at 0, 1, 2, 3.5, 5, 7.5, 10, 12.5, 15, 20, 30 for determination...
The DNA machine unwinds RNA; selectively recognizes targeted fragment; attracts fluorogenic substrate and catalytically multiplies fluorescent signal.
This study investigated the association between synthetic ovarian hormone use [i.e., oral contraceptive (OC) pill] and basal C-reactive protein (CRP), peripheral blood immune cell subsets, circulating pro- anti-inflammatory cytokine concentrations in elite female athletes. Elite athletes (n = 53) selected Rio Summer Olympic squads participated this study; 25 were taking an OC (AthletesOC) 28 naturally hormonally cycling (AthletesNC). Venous samples collected at rest for determination of sex...
The aim of this study was to determine the influence training volume alterations on diversity and composition gut microbiome in a free-living cohort middle-distance runners. Fourteen highly-trained runners (n = 8 men; V˙O2peak 70.1 ± 4.3 ml·kg·min-1; n 6 women, V˙O2peak: 59.0 3.2 ml·kg·min-1) completed three weeks normal (NormTr), high-volume (HVolTr; 10, 20 30% increase during each successive week from NormTr), one-week taper (TaperTr; 55% exponential reduction HVolTr three). Faecal samples...