A5036861946- Cardiovascular Health and Risk Factors
- Cardiovascular Disease and Adiposity
- Cardiac Health and Mental Health
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Obesity, Physical Activity, Diet
- Cardiac and Coronary Surgery Techniques
- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Health disparities and outcomes
- Cardiac Imaging and Diagnostics
- Lipoproteins and Cardiovascular Health
- Cardiovascular Health and Disease Prevention
- Telomeres, Telomerase, and Senescence
- Stress Responses and Cortisol
- Angiogenesis and VEGF in Cancer
- Liver Disease Diagnosis and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Mobile Health and mHealth Applications
- Heart Rate Variability and Autonomic Control
- Nutritional Studies and Diet
- Physical Activity and Health
- Mesenchymal stem cell research
Northside Hospital
2023
Emory University
2013-2020
Emory Clinic
2015-2019
Emory Healthcare
2017-2018
Johns Hopkins Medicine
2018
Johns Hopkins University
2018
Emory and Henry College
2016-2017
Morehouse School of Medicine
2012-2017
Winship Cancer Institute
2016-2017
Tulane University
2016
OBJECTIVE This study examined the prognostic significance of diabetes and microvascular complications in patients with heart failure preserved ejection fraction (HFpEF). RESEARCH DESIGN AND METHODS analysis included 3,385 (mean age 69 ± 9.6 years; 49% male; 89% white) HFpEF from Treatment Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist Trial (TOPCAT). Diabetes were ascertained by self-reported history medical record review. Microvascular neuropathy, nephropathy,...
Background The associations between high‐sensitivity troponin I (hsTnI) levels and coronary artery disease (CAD) severity progression remain unclear. We investigated whether there is an association hsTnI angiographic of CAD the predictive value level for incident cardiovascular outcomes independent severity. Methods Results In 3087 patients (aged 63±12 years, 64% men) undergoing cardiac catheterization without evidence acute myocardial infarction, was calculated by number major arteries with...
Background Food deserts ( FDs ), defined as low-income communities with limited access to healthy food, are a growing public health concern. We evaluated the impact of living in on incident cardiovascular events. Methods and Results recruited 4944 subjects (age 64±12, 64% male) undergoing cardiac catheterization into Emory Cardiovascular Biobank. Using US Department Agriculture definition FD , we determined whether their residential addresses had (1) poor (2) low income, or (3) both (= )....
Leukocyte telomere length (LTL) is a biological marker of aging, and shorter LTL associated with adverse cardiovascular outcomes. Reduced regenerative capacity has been proposed as mechanism. Bone marrow-derived circulating progenitor cells are involved in tissue repair regeneration.Main objective this study was to examine the relationship between their impact on outcomes.We measured by quantitative polymerase chain reaction 566 outpatients (age: 63±9 years; 76% men) coronary artery disease....
Cardio Metabolic Syndrome (CMS), also known as insulin resistance syndrome or metabolic X, is a combination of disorders risk factors that essentially includes diabetes mellitus, systemic arterial hypertension, central obesity and hyper-lipidemia.Common to these diseases metabolism the associated development atherosclerotic cardiovascular disease (ASCVD).Studies have shown strong link between CMS increased prevalence peripheral vascular diseases, coronary artery myocardial infarctions well...
Subcutaneous ICD in Dialysis Patients Background Although the subcutaneous (S‐ICD®) is an attractive alternative patients with end‐stage renal disease (ESRD), data on S‐ICD outcomes dialysis are lacking. Methods cardiomyopathy undergoing implantation our center were stratified by need for chronic at time of implant. The primary endpoint was incidence death, heart failure hospitalization or appropriate shocks, and secondary endpoints inappropriate shocks implant related complications...
Endogenous regenerative capacity, assessed as circulating progenitor cell (PC) numbers, is an independent predictor of adverse outcomes in patients with cardiovascular disease. However, their predictive role heart failure (HF) remains controversial. We the relationship between number PCs and pathogenesis severity HF impact on incident events.We recruited 2049 adults which 651 had diagnosis. were enumerated by flow cytometry CD45med+ blood mononuclear cells expressing CD34, CD133, vascular...
Background Educational attainment is an indicator of socioeconomic status and inversely associated with coronary artery disease risk. Whether educational level ( EAL ) among patients influences outcomes remains understudied. Methods Results Patients undergoing cardiac catheterization had their highest assessed using options elementary/middle school, high college, or graduate education. Primary outcome was all‐cause mortality secondary were a composite cardiovascular death/non‐fatal...
Mobile health (mHealth) is the utilisation of mobile technologies in healthcare and has particular relevance improving lifestyle behaviours which may ultimately reduce cardiovascular disease risk. Various intervention studies for example integrate self-monitoring diet physical activity with text messaging systems to improve intermediate outcomes. Currently future progress mHealth formal diagnostic therapeutic roles pending includes need validate standardise accelerometer heart rate data from...
Background Although diastolic blood pressure ( DBP ) is independently associated with an increased risk of adverse cardiovascular outcomes in the general population, it unclear if a similar relationship exists patients heart failure preserved ejection fraction. Methods and Results This analysis included 1703 (mean age, 72±10 years; 50% men; 78% white) fraction enrolled TOPCAT (Treatment Preserved Cardiac Function Heart Failure With Aldosterone Antagonist) Trial from Americas who were treated...
Although high resting heart rates are associated with adverse outcomes in failure reduced ejection, the reports for preserved ejection fraction (HFpEF) conflicting. A secondary analysis was conducted order to examine relationship between rate and 2705 patients (mean age = 68 ± 10 years; 47% men; 88% white) HFpEF who were sinus rhythm from Treatment of Preserved Cardiac Function Heart Failure an Aldosterone Antagonist Trial (TOPCAT). Baseline obtained baseline electrocardiogram data. Outcomes...