Hao Ling

ORCID: 0000-0002-7796-5308
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About
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Research Areas
  • Extracellular vesicles in disease
  • MicroRNA in disease regulation
  • Cardiovascular Disease and Adiposity
  • Immune cells in cancer
  • Atherosclerosis and Cardiovascular Diseases
  • Cancer-related molecular mechanisms research
  • Opportunistic and Delay-Tolerant Networks
  • Mobile Ad Hoc Networks
  • Circular RNAs in diseases
  • AI in cancer detection
  • Cancer Research and Treatments
  • Indoor and Outdoor Localization Technologies
  • Advanced Measurement and Detection Methods
  • Cardiovascular Effects of Exercise
  • Infrared Target Detection Methodologies
  • Advanced X-ray and CT Imaging
  • Energy Efficient Wireless Sensor Networks
  • Liver Disease Diagnosis and Treatment
  • Congenital heart defects research
  • Metabolomics and Mass Spectrometry Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Adipokines, Inflammation, and Metabolic Diseases
  • Optical Systems and Laser Technology
  • Domain Adaptation and Few-Shot Learning
  • Photoacoustic and Ultrasonic Imaging

Sichuan University
2025

West China Hospital of Sichuan University
2025

Second Affiliated Hospital of Jilin University
2020-2023

Harbin Medical University
2014-2022

Fourth Affiliated Hospital of Harbin Medical University
2014-2022

Nanjing Institute of Technology
2019

East China Normal University
2018

Harbin Institute of Technology
2011-2012

Acute coronary syndrome (ACS) is a serious threat to public health. Based on clinical manifestations, ACS can be classified into unstable angina (UA) pectoris and acute myocardial infarction (AMI). The purpose of this study was explore the possibility using serum exosomal microRNA (miR)-126, miR-21, phosphatase tensin homolog (PTEN) expression levels as biomarkers UA AMI investigate whether these were positively correlated with severity stenosis based Gensini score. Exosomes isolated by...

10.3389/fphys.2020.00654 article EN cc-by Frontiers in Physiology 2020-06-11

To evaluate the diagnostic value of ultrasound radiomics in distinguishing between benign and malignant breast nodules women who have undergone silicone augmentation. A retrospective study was conducted 99 detected by 93 had The data were collected 1 January 2006 September 2023. allocated into a training set (n = 69) validation 30). Regions interest (ROIs) manually delineated using 3D Slicer software, radiomic features extracted selected Python programming. Eight machine learning algorithms...

10.3390/curroncol32010029 article EN cc-by Current Oncology 2025-01-03

Background Nodal/TGF-Lefty signaling pathway has important effects at early stages of differentiation human embryonic stem cells in directing them to differentiate into different lineages. LEFTY, one transforming growth factors the pathway, plays an role development heart. The aim this work was find evidence on whether Lefty variations are associated with congenital heart diseases (CHD). Methods We sequenced gene for 230 Chinese Han CHD patients and evaluated SNPs rs2295418, rs360057...

10.1371/journal.pone.0104535 article EN cc-by PLoS ONE 2014-08-11

Purpose Acute coronary syndrome presents as unstable angina (UA) or acute myocardial infarction (AMI). We explored the use of exosomal miR-122-5p a biomarker for UA and AMI determined whether its expression level is positively correlated with severity stenosis.Methods This study enrolled 34 patients AMI, 31 UA, 22 control subjects. qPCR was used to detect levels serum miR-122-5p.Results The in significantly higher than that group, differed between patients. Receiver operating characteristic...

10.1080/1354750x.2020.1803963 article EN Biomarkers 2020-07-29

An improved IR target-tracking algorithm based on mean shift is proposed herein, which combines the mean-shift-based gradient-matched searching strategy with a feature-classification-based tracking algorithm. target representation model constructed by considering likelihood ratio of gray-level features and local background as weighted value original kernel histogram region. expression for mean-shift vector in this derived, criterion updating presented. Experimental results show that improves...

10.1364/ao.51.005051 article EN Applied Optics 2012-07-10

The fundamental operation in mobile wireless communication is to establish links between neighbor devices. neighor discovery problem non-trivial, especially under an urban environment. Various background scenarios, e.g., inside vehicles, at open-air squares, and the supermarket, lead complex requirements. Discovery among fast moving devices requires immediate exchange of emergency messages (minimum latency), while low-speed crowded environments pay more attention energy efficiency. Typical...

10.1109/access.2018.2878251 article EN cc-by-nc-nd IEEE Access 2018-01-01

Cardiovascular diseases continue to be the foremost cause of death among both males and females worldwide.[1] Coronary artery disease (CAD) represents a major subtype cardiovascular diseases. Recent evidence has highlighted worldwide increase in incidence CAD clinical manifestations regardless geographical region.[2] Despite steady decline mortality western countries over past few decades, approximately one-third population suffering from will succumb disease. Rapid accurate diagnostic...

10.1097/cm9.0000000000001202 article EN cc-by-nc-nd Chinese Medical Journal 2020-11-23

Based on the wave theory of aberrations, Point Spread Functions (PSFs) optical synthetic aperture imaging system disturbed by some such as Piston error, Tilt spherical aberration, astigmatism, were analyzed. Additionally, analytical expressions central value PSF (CVPSF) error and deduced, simulated MATLAB. The results show that when one sub-aperture an N identical sub-apertures array is fluctuates periodically. Furthermore, decreased aberration or astigmatism can be significantly compensated...

10.1117/12.904731 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2011-11-23

Effect of mathematical misorientation on microstructures and properties bicrystal superalloy RR2086 have been investigated. Prior to thermal exposure, precipitates modified bicrystals (BXs) at grain boundaries were mainly MCs. After the a reasonable amount discontinuous blocky M23C6 which embedded in γ' layer along boundary found BXs. This type is known be ductile creep-resistant. No cellular appeared during exposure. structure results improved creep performance high-angle BXs compared their...

10.1088/2053-1591/aaceb4 article EN Materials Research Express 2018-06-25

Synergistic Cancer Therapy In article number 2100950 by Bin Qin, Jin Sun, and co-workers, a both-in-one hybrid bacteria, wherein the chemotherapeutic drug doxorubicin is integrated onto surface of glucose dehydrogenase-overexpressed non-pathogenic Escherichia coli strain, potentiates stimulated systemic antitumor immune responses, thereby significantly inhibiting tumor metastasis, postsurgical regrowth, primary/distal relapse in four different models.

10.1002/adhm.202170102 article EN Advanced Healthcare Materials 2021-11-01

Medical scene graph contributes to cognitive tasks such as question answering. An automatic medical generator can annotate images with graphs conveniently. end-to-end model is proposed, which contains an based on and surgery records. The novel extract symptom information of the from records via name entity recognition then convert it into graphs. content format are pre-defined according features images. A (MSG) dataset also produced. 116 where each includes 6 30 entities. Experiments show...

10.1109/bibm52615.2021.9669882 article EN 2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) 2021-12-09
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