Emmanouil Korakas

ORCID: 0000-0002-7813-5488
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About
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Research Areas
  • Cardiovascular Health and Disease Prevention
  • Diabetes Treatment and Management
  • Cardiovascular Function and Risk Factors
  • Blood Pressure and Hypertension Studies
  • Liver Disease Diagnosis and Treatment
  • COVID-19 Clinical Research Studies
  • Climate Change and Health Impacts
  • Metabolism, Diabetes, and Cancer
  • Diet, Metabolism, and Disease
  • Acute Ischemic Stroke Management
  • Liver Disease and Transplantation
  • Diet and metabolism studies
  • Cardiovascular Disease and Adiposity
  • Long-Term Effects of COVID-19
  • Pharmacology and Obesity Treatment
  • Neurological Disorders and Treatments
  • Advanced Glycation End Products research
  • Biochemical effects in animals
  • Cardiac Imaging and Diagnostics
  • Coenzyme Q10 studies and effects
  • Cardiovascular Effects of Exercise
  • Psoriasis: Treatment and Pathogenesis
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Cerebrovascular and Carotid Artery Diseases
  • Diabetes Management and Research

National and Kapodistrian University of Athens
2019-2025

University General Hospital Attikon
2018-2025

Sotiria General Hospital
2023-2024

The effect of different diet patterns on psoriasis (PSO) and psoriatic arthritis (PSA) is unknown. Τhe aim our study was to evaluate the effectiveness a Mediterranean (MD) Ketogenic (KD), in patients with PSO PSA. Twenty-six were randomly assigned start either MD or KD for period 8 weeks. After 6-week washout interval, two groups crossed over other type At end this study, resulted significant reduction weight (p = 0.002, p < 0.001, respectively), BMI 0.006, waist circumference (WC) total...

10.3390/ijms25052475 article EN International Journal of Molecular Sciences 2024-02-20

Background and Objectives: Glucagon-like peptide-1 receptor agonists (GLP-1RA) sodium-glucose cotransporter-2 inhibitors (SGLT-2i) are cardioprotective drugs. We investigated their effects on left atrial function, a major determinant of cardiac diastolic dysfunction in type 2 diabetes mellitus. also explored the association changes arterial stiffness with those LA strain after treatment. Materials Methods: A total 200 patients (59.5 ± 9.1 year old, 151 male) mellitus treated metformin were...

10.3390/medicina60030395 article EN cc-by Medicina 2024-02-26

Hydroxytyrosol reduces low-density lipoprotein oxidation, contributing to prevention of atherosclerosis progression.In a prospective, crossover, double-blind, placebo-controlled trial, 30 chronic coronary artery syndrome (CCAS) patients were randomized 4 capsules/day, containing 412.5 mg olive oil with 2.5 hydroxytyrosol (OOHT) each one or placebo for 1 month and then crossed over the alternate treatment (placebo OOHT). We measured (a) perfused boundary region (PBR) sublingual arterial...

10.1111/eci.13983 article EN cc-by European Journal of Clinical Investigation 2023-03-13

Abstract Background/Introduction Coronavirus disease 2019 (COVID-19) has been associated with impaired subclinical markers of endothelial and vascularfunction. Purpose We investigated whether intervention Endocalyx (Microvascular Health Solutions),a dietary supplement containing glycosaminoglycans fucoidan, can improve glycocalyx integrity,arterial stiffness, coronary microcirculationin patients after COVID-19 infection. Methods Fiftypatients within 15 days a confirmed mild-to-moderate...

10.1093/ehjci/jeae333.222 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

Background We investigated the effects of combined treatment with glucagon like peptide‐1 receptor agonists (GLP‐1RA) and sodium‐glucose cotransporter‐2 inhibitors (SGLT‐2i) on NT‐proBNP (N‐terminal pro‐brain natriuretic peptide), GDF‐15 (growth differentiation factor 15), MOTS‐c (mitochondrial‐derived peptide‐c) in patients type 2 diabetes (T2D) high or very cardiovascular risk. Methods studied 163 consecutive who were treated insulin (n=40), liraglutide (n=41), empagliflozin (n=42), their...

10.1161/jaha.124.039129 article EN cc-by-nc-nd Journal of the American Heart Association 2025-02-26

Metabolic-dysfunction Associated Steatotic Liver Disease (MASLD) has been associated with increased cardiovascular risk. The aim of this Randomized Double-blind clinical Trial was to evaluate the effects coenzyme-Q10 supplementation in patients MASLD terms endothelial, vascular and myocardial function.

10.1186/s12933-024-02326-8 article EN cc-by Cardiovascular Diabetology 2024-07-10

AbstractIntroduction: Usage of automated insulin delivery systems is increasing for the treatment people with type 1 diabetes (T1D). This study compared long-term cost-effectiveness Advanced Hybrid Closed Loop MiniMed 780G (AHCL) system versus sensor augmented pump (SAP) predictive low glucose management (PLGM) or multiple daily injections (MDI) plus intermittently scanned continuous monitoring (isCGM) in T1D Greece. Methods: Analyses were performed using IQVIA CORE Diabetes Model, clinical...

10.1089/dia.2021.0443 article EN Diabetes Technology & Therapeutics 2021-12-28

Abstract Context The cardiovascular benefits of semaglutide are established; however, its effects on surrogate vascular markers and liver function not known. Objective To investigate the vascular, endothelial, in patients with type 2 diabetes (T2DM) nonalcoholic fatty disease (NAFLD). Methods Overall, 75 consecutive subjects T2DM NAFLD were enrolled: 50 received 1 mg (treatment group) 25 dipeptidyl peptidase 4 inhibitors (control group). All underwent a clinical, hepatic examination...

10.1210/jendso/bvae122 article EN cc-by Journal of the Endocrine Society 2024-07-01

To evaluate the potential association between endothelial glycocalyx damage, as well arterial stiffness, and retinal changes on optical coherence tomography (OCT) OCT-angiography (OCT-A) in patients with type 2 diabetes mellitus (DM).

10.3390/jpm14090995 article EN Journal of Personalized Medicine 2024-09-19

Osteoprotegerin (OPG) and osteopontin (OPN) are vascular calcification inhibitors with a known role in the atherosclerotic inflammatory process. We investigated their relationship adverse outcomes (restenosis/adverse cardiovascular events) after endovascular revascularisation of patients peripheral arterial disease (PAD).203 consecutive were enrolled PAD group (PADG) 78 age sex-matched subjects less than two risk factors served as control (COG). PADG underwent standard medical assessment at...

10.1186/s12933-022-01605-6 article EN cc-by Cardiovascular Diabetology 2022-09-01

Abstract Background Bullous pemphigoid is the most common bullous chronic autoimmune skin disease. Recent studies have suggested dipeptidyl-peptidase 4 inhibitors as possible predisposing agents of pemphigoid. The objective our study was to prospectively estimate association between gliptins and development Methods We conducted a prospective which included all patients diagnosed with biopsy-proven in Dermatology Department hospital April 1, 2009 December 31,2019. diagnosis based on specific...

10.1186/s12902-021-00689-7 article EN cc-by BMC Endocrine Disorders 2021-02-11

Familial partial lipodystrophy (FPLD) is a rare syndrome in which patient’s phenotype not merely dependent on the specific genetic mutation, but it also defined by combination of other demographic, environmental and factors. In this prospective observational study Greek referral center, we enrolled 39 patients who fulfilled clinical criteria FPLD. A analysis was conducted, included sequence deletion/duplication analyses LMNA PPRARG genes, along with anthropometric metabolic parameters. The...

10.3390/ijms241512045 article EN International Journal of Molecular Sciences 2023-07-27

Background: Physicians’ exercise habits vary across different medical specialties and health service infrastructure. We assessed physicians’ performance according to the recommendations of 2020 European Society Cardiology Guidelines. Methods: This cross-sectional study comprised 742 physicians Athens Medical Association (AMA), Greece. Utilizing a self-administered questionnaire, habits, demographics, specialty, infrastructure [Hellenic National Health care System (HNHS) or Private (PS)] were...

10.1177/15598276241267213 article EN American Journal of Lifestyle Medicine 2024-07-26
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