A5014280857- Diabetes Treatment and Management
- Diabetic Foot Ulcer Assessment and Management
- Diabetes Management and Research
- Metabolism, Diabetes, and Cancer
- Cardiovascular Health and Disease Prevention
- Wound Healing and Treatments
- Diet and metabolism studies
- Heart Rate Variability and Autonomic Control
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pressure Ulcer Prevention and Management
- Diabetes and associated disorders
- Pain Mechanisms and Treatments
- Blood Pressure and Hypertension Studies
- Pancreatic function and diabetes
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Adipokines, Inflammation, and Metabolic Diseases
- Cerebrovascular and Carotid Artery Diseases
- COVID-19 Clinical Research Studies
- Peripheral Artery Disease Management
- Nutritional Studies and Diet
- Adipose Tissue and Metabolism
- Pharmacology and Obesity Treatment
- Botulinum Toxin and Related Neurological Disorders
- Lipoproteins and Cardiovascular Health
Laiko General Hospital of Athens
2016-2025
National and Kapodistrian University of Athens
2016-2025
University of Ioannina
2017-2023
Pasteur Hellenic Institute
2023
Senologic Hellenic Society
2023
General Hospital of Athens G. Genimatas
2023
Papageorgiou General Hospital
2023
Aristotle University of Thessaloniki
2023
Hippocration General Hospital
2017-2022
Sotiria General Hospital
2022
OBJECTIVE To investigate the efficacy, safety, and tolerability of oral semaglutide added to insulin with or without metformin. RESEARCH DESIGN AND METHODS Patients type 2 diabetes uncontrolled on metformin were randomized 3 mg (N = 184), 7 182), 14 181) placebo 184) in a 52-week, double-blind trial. End points change from baseline week 26 HbA1c (primary) body weight (confirmatory secondary). Two estimands defined: treatment policy (effect regardless trial product discontinuation rescue...
The rate at which people eat has been suggested to be positively associated with obesity, although appetite and related gut hormones have not measured. objective of the study was determine whether eating same meal varying speeds elicits different postprandial peptide responses.This a crossover clinical research facility.Seventeen healthy adult male volunteers participated in study.A test consisting 300 ml ice cream (675 kcal) consumed random order on two sessions by each subject: duration...
To study the prevalence of pathogenic organisms and outcome methicillin-resistant Staphylococcus aureus (MRSA) infection in foot ulcers diabetic patients.A retrospective analysis wound swabs taken from infected patients, selected an outpatient clinic. Seventy-five patients (79 ulcers) with positive were included. Size ulcer time to healing, particular for MRSA-infected ulcers, measured all patients.Gram-positive aerobic bacteria commonest micro-organism isolated (56.7%) followed by...
OBJECTIVE—To compare survival rates after first amputation between patients with and without diabetes. RESEARCH DESIGN AAND METHODS—We performed a retrospective study of all nontraumatic amputations at our center in the years 1990–1995 (n = 100) 151) Survival status was assessed from until 31 December 2001. RESULTS—Altogether, 61% 54.3% those diabetes died 5.2 (4.5–5.8) 5.3 (4.7–5.9) [mean (95% CI)] amputation, respectively (P 0.80). not different controlling for level (major versus minor)...
The extent to which atherosclerosis is accelerated in chronic inflammatory diseases not established. We compared preclinical rheumatoid arthritis with diabetes mellitus, a known coronary heart disease equivalent.Endothelial function, arterial stiffness, carotid intima-media thickness, and analysis of atheromatous plaques were examined 84 patients without cardiovascular versus healthy controls matched for age, sex, traditional risk factors, as well 48 duration patients. Rheumatoid associated...
In patients with uncontrolled type 2 diabetes on basal insulin, prandial insulin may be initiated. We assessed the efficacy and safety of initiating degludec/liraglutide fixed-ratio combination (IDegLira) versus basal-bolus insulin.A phase 3b trial examined glargine (IGlar U100) 20-50 units/day metformin, randomized to IDegLira or IGlar U100 aspart ≤4 times per day.Glycated hemoglobin (HbA1c) decreased from 8.2% (66 mmol/mol) 6.7% (50 (67 (estimated treatment difference [ETD] -0.02% [95% CI...
Serum inflammatory markers, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), white blood cells (WBC), and procalcitonin (PCT), have been used for the diagnosis of foot infections in patients with diabetes. However, little is known about their changes during treatment infections. The aim this prospective study was to examine performance serum markers follow-up osteomyelitis. A total 61 (age 63.1 ± 7.0 years, 45 men 16 women, 7 type 1 54 2 diabetes) untreated infection (34...
Objective To examine the effect of α-lipoic acid on neuropathic symptoms in patients with diabetic neuropathy (DN). Methods Patients painful DN were treated 600 mg/day acid, orally, for 40 days. Neuropathy Symptom Score (NSS), Subjective Peripheral Screen Questionnaire (SPNSQ) and douleur neuropathique (DN)4 questionnaire scores assessed at baseline day 40. Quality-of-life treatment effects by Brief Pain Inventory (BPI), Neuropathic (NPSI) Sheehan Disability Scale (SDS). Changes body weight,...
The epidemiologic link between schizophrenia (SCZ) and type 2 diabetes (T2D) remains poorly understood. Here, we investigate the presence extent of a shared genetic background SCZ T2D using genome-wide approaches. We performed association study (GWAS) polygenic risk score analysis in Greek sample collection (GOMAP) comprising three patient groups: only (n = 924), 822), comorbid 505); samples from two separate cohorts were used as population-based controls 1,125). summary statistics...
Abstract Objective: The aim of this study was to test the hypothesis that baroreflex sensitivity (BRS), assessed by indirect measurement aortic pressure, is blunted in obesity. Additionally, potential effect cardiac autonomic nervous system (ANS) activity, compliance, and metabolic parameters on BRS obese subjects investigated. Research Methods Procedures: A group 30 women with BMI >30 kg/m 2 a controls <25 were examined. estimated sequence technique, ANS activity short‐term spectral...
To examine differences in telomere (terminal restriction fragment [TRF]) length and pulse wave velocity (PWV)--an index of arterial stiffness--in patients with type 2 diabetes without microalbuminuria (MA).A total 84 men diabetes, 40 MA 44 (aged 63.5 +/- 9.0 vs. 61.2 9.8 years), were studied. TRF was determined white blood cells. defined as albumin excretion rate (AER) the range 30-300 mg/24 h at least two three 24-h urine collections. PWV assessed using applanation tonometry. Markers...
OBJECTIVE Because many patients with diabetic macular edema (DME) do not respond to focal/grid laser photocoagulation, the only currently approved treatment, alternatives are needed. Based on encouraging preliminary findings, we aimed assess efficacy and safety of anti–tumor necrosis factor (TNF) monoclonal antibody infliximab in this condition. RESEARCH DESIGN AND METHODS This was a single-center, double-blind, randomized, placebo-controlled, crossover study. Eleven sight-threatening DME...