A5034143911- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Cancer-related molecular mechanisms research
- Metastasis and carcinoma case studies
- Colorectal Cancer Screening and Detection
- Esophageal Cancer Research and Treatment
- Gastrointestinal Tumor Research and Treatment
- RNA modifications and cancer
- Cancer-related Molecular Pathways
- Cancer Diagnosis and Treatment
- Dysphagia Assessment and Management
- Colorectal Cancer Surgical Treatments
- Gastroesophageal reflux and treatments
- Kruppel-like factors research
- Plant Disease Resistance and Genetics
- Wnt/β-catenin signaling in development and cancer
- Colorectal and Anal Carcinomas
- Cardiac, Anesthesia and Surgical Outcomes
- Tracheal and airway disorders
- Genetic and Kidney Cyst Diseases
- AI in cancer detection
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Mechanisms and Therapy
- Medical Research and Treatments
- Neuroendocrine Tumor Research Advances
Wenzhou Medical University
2018-2024
Wenzhou Central Hospital
2013-2024
Second Affiliated Hospital of Zhejiang University
2024
Shanghai University
2024
First Affiliated Hospital of Gannan Medical University
2023
Changes in gastric mucosa caused by Helicobacter pylori (H. pylori) infection affect the observation of early cancer under endoscopy. Although previous researches reported that computer-aided diagnosis (CAD) systems have great potential H. infection, their explainability remains a challenge.We aim to develop an explainable artificial intelligence system for diagnosing (EADHI) and giving diagnostic basis endoscopy.A case-control study.We retrospectively obtained 47,239 images from 1826...
Several recent studies have found that the efficacy of computer-aided polyp detection (CADe) on adenoma rate (ADR) diminished in real-world settings. The role unmeasured factors AI-human interaction, such as monitor approaches, remains unknown. This study aimed to validate effectiveness CADe real world and assess impact approaches.
To compare the effect of radiofrequency ablation (RFA) combined with transcatheter arterial chemoembolization (TACE) alone for treatment 3 - 5 cm hepatocellular carcinoma (HCC).From January 2006 to March 2010, sixty-two HCC patients were randomly treated RFA TACE (n = 32) or 30). This group included who had Child-Pugh class A B three fewer tumors, in which just one tumor size was diameter, and no evidence extrahepatic metastasis macrovascular invasion. The follow up ranged from 9 39 months....
Colorectal cancer is one of the leading causes death worldwide. Wnt/beta-catenin signalling pathway plays a central role in normal cellular responses, making it potent target therapy. Study was taken to assess whether ellagic acid modulates and CDK8 activity colon cells. Effect on viability cell lines (HT 29 HCT 116), were assessed by MTT assay its influence CDK8, ?-catenin, p-?-catenin, axin1 2, survivin, c-Myc cyclin D1 expressions determined western blotting. The levels also analysed...
It is important to predict the risk of gastric cancer (GC) for endoscopists because early detection GC determines selection best treatment strategy and prognosis patients. The study aimed evaluate utility a predictive nomogram based on Kyoto classification gastritis GC.It was retrospective that included 2639 patients who received esophagogastroduodenoscopy serum pepsinogen (PG) assay from January 2019 November at Endoscopy Center Department Gastroenterology, Wenzhou Central Hospital. Routine...
Abstract Background A novel scoring system and screening procedure for gastric cancer (GC) was proposed based on the national conditions of China, which state that endoscopy professionals facilities are relatively limited compared with large Chinese population. Methods used to retrospectively analyse patients who met from April 2017 December 2019 in our hospital. We divided all into three groups: low-risk group (0–11 scores), medium-risk (12–16 high-risk (17–23 scores). Statistical analysis...
Abstract Background and Aim The implementation of computer‐aided detection (CAD) devices in esophagogastroduodenoscopy (EGD) could autonomously identify gastric precancerous lesions neoplasms reduce the miss rate prospective trials. However, there is still insufficient evidence their use real‐life clinical practice. Methods A real‐world, two‐center study was conducted at Wenzhou Central Hospital (WCH) Renmin Wuhan University (RHWU). High biopsy low strategies were adopted, CAD applied 2019...
Isolated metachronous metastatic small intestinal squamous cell carcinoma is rare, and it sometimes difficult to determine whether by immunohistochemistry alone. At present, there no literature analyzing the gene profile of carcinoma.We met a 62-year-old male patient who had history lung surgery. He was admitted for simultaneous jejunal all carcinoma, gastric adenocarcinoma, rectal adenocarcinoma. Endoscopic resection performed cancer cancer, surgical docetaxel adjuvant chemotherapy were...
Background: The mucosal changes of early gastric cancers (EGC) are slight and difficult to be recognized, leading a high miss rate. Artificial intelligence (AI) systems have the potential improve detection EGC. Here, we report case cancer discovered by an endoscopist with assistance AI system. Case presentation: A 67-year-old male patient came our hospital for Esophagogastroduodenoscopy (EGD) due routine physical examination. He had previously been healthy but was treated Helicobacter pylori...
Background: The implementation of computer-aided detection (CAD) devices in esophagogastroduodenoscopy (EGD) could autonomously identify gastric precancerous lesions and neoplasms, reduce the miss rate neoplasms prospective tandem trials. However, there is still insufficient evidence their use real-life clinical practice. Method: A real-world, two-center, large-volume, pragmatic study was conducted at Wenzhou Central Hospital (WCH) Renmin Wuhan University (RHWU). Random biopsy target were...
Objective To investigate the clinical effects of stent-laparoscopy approach in treatment elderly patients with malignant colorectal obstruction. Methods Clinical data 55 hospitalized cancer-induced bowel obstruction Wenzhou Central Hospital from January 2009 to 2014 were evaluated retrospectively.All treated expandable metallic stents for remission obstruction.Patients divided laparoscopy surgery-observation group (n=14) receiving laparoscopic surgery after decompression and...
Objective To explore the clinical value of a new scoring system for gastric cancer screening in hospital visits. Methods A was used to retrospectively analyze data patients who visited Wenzhou Central Hospital various digestive symptoms from April 2017 August 2018 and met requirements. All were divided into three groups according grading results system: low-risk group (0-11 points), medium-risk (12-16 points) high-risk (17-23 points). A comparative analysis performed on detection...
Background: The mucosal changes of early gastric cancers (EGC) are slight and difficult to be recognized, leading a high miss rate. Artificial intelligence (AI) systems have the potential improve detection rate EGC. Here, we reported case EGC discovered by an endoscopist with assistance AI system. Case presentation: A 67-year-old male patient came our hospital for Esophagogastroduodenoscopy (EGD) due routine physical examination. He had previously been healthy but was treated Helicobacter...
Abstract Background and Aim. It is of importance to predict the risk gastric cancer (GC) for endoscopists because early detection GC determines selection best treatment strategy prognosis patients. The aim study was evaluate utility a predictive nomogram based on Kyoto classification gastritis GC. Methods. retrospective that included 2639 patients who received esophagogastroduodenoscopy serum pepsinogen (PG) assay from January 2020 November at Endoscopy Center Department Gastroenterology,...