- Uterine Myomas and Treatments
- Cervical Cancer and HPV Research
- Endometriosis Research and Treatment
- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Health Literacy and Information Accessibility
- Preterm Birth and Chorioamnionitis
- Social Media in Health Education
- Reproductive System and Pregnancy
- AI in cancer detection
- Cancer Immunotherapy and Biomarkers
- MicroRNA in disease regulation
- Reproductive tract infections research
- Pelvic floor disorders treatments
- CAR-T cell therapy research
- Monoclonal and Polyclonal Antibodies Research
- Cancer-related molecular mechanisms research
- Maternal and fetal healthcare
- Antiplatelet Therapy and Cardiovascular Diseases
- Radiomics and Machine Learning in Medical Imaging
- Neuroblastoma Research and Treatments
- Immunotherapy and Immune Responses
- Angiogenesis and VEGF in Cancer
- Patient-Provider Communication in Healthcare
- Lung Cancer Treatments and Mutations
Hallym University Medical Center
2017-2025
Hallym University Kangnam Sacred Heart Hospital
2015-2025
Hallym University
2013-2025
Incheon St. Mary's Hospital
2023
Konkuk University Medical Center
2021
Chung-Ang University Hospital
2021
Hallym University Sacred Heart Hospital
2021
Soonchunhyang University
2021
Johns Hopkins University
2020
Seoul St. Mary's Hospital
2011-2013
Abstract Colposcopy is widely used to detect cervical cancers, but experienced physicians who are needed for an accurate diagnosis lacking in developing countries. Artificial intelligence (AI) has been recently computer-aided showing remarkable promise. In this study, we developed and validated deep learning models automatically classify neoplasms on colposcopic photographs. Pre-trained convolutional neural networks were fine-tuned two grading systems: the intraepithelial neoplasia (CIN)...
Attitudes Regarding HPV Vaccinations of Children among Mothers with Adolescent Daughters in KoreaThe aim this study, carried out before the beginning human papillomavirus (HPV) vaccinations as a National Immunization Program (NIP) Korea 2016, is to assess ranges perceptions and personal experience their influences on attitudes regarding children, mothers adolescent (9-14 years age) daughters Korea.From November 2015 February we distributed written questionnaire who had aged 9-14 years.The...
Globally, YouTube is one of the most popular websites, and content not restricted to entertainment. The purpose this study was assess quality information in videos pertaining hysterectomy.
Bacterial vaginosis (BV) is the most common disease in women of childbearing age and caused by growth abnormal microbiota vagina. Probiotic consumption can be an effective alternative treatment to preserve or improve vaginal health. In present study, MED-01, a complex five strains probiotic candidates isolated from vagina Korean women, was used. This study designed as 12-week, randomized, multicenter, double-blind, placebo-controlled clinical trial evaluate efficacy safety MED-01 on A total...
This fifth revised version of the Korean Society Gynecologic Oncology practice guidelines for management cervical cancer incorporates recent research findings and changes in treatment strategies based on 4.0 released 2020. Each key question was developed by focusing notable insights crucial contemporary issues field cancer. These questions were evaluated their significance impact current finalized through voting development committee. The selected as follows: efficacy safety immune...
We describe the updated Korean Society of Gynecologic Oncology (KSGO) practice guideline for management cervical cancer, version 5.1. The KSGO announced fifth its clinical guidelines cancer in March 2024. selection key questions and systematic reviews were based on data available up to December 2022. Between 2023 2024, substantial findings from large-scale trials new advancements research remarkably emerged. Therefore, existing 5.0, we with newly accumulated added 4 reflecting latest...
CT83, a cancer-testis antigen, has emerged as potential biomarker and therapeutic target in various cancers. This study explores its expression role cervical adenocarcinoma progression prognosis. CT83 was analyzed cancer cell lines using quantitative PCR Western blotting. Functional assays demonstrated that overexpression (OE) promotes proliferation, migration, invasion, epithelial–mesenchymal transition (EMT) cells while also upregulating PD-L1 expression. Conversely, knockdown reduced...
Chlamydia infection in acute pelvic inflammatory disease (PID) is associated with serious complications including ectopic pregnancy, tubal infertility, Fitz-Hugh-Curtis syndrome and tubo-ovarian abscess (TOA). This study compared clinical laboratory data between PID without chlamydia infection.The medical records of 497 women who were admitted 2002 2011 reviewed. The patients divided into two groups (PID infection), which terms the patients' characteristics, presentation, findings,...
Abstract High mobility group box 1 (HMGB1) is a prototypic alarmin and plays an important role in the pathogenesis of inflammatory process spontaneous preterm birth. This study was conducted to compare levels HMGB1 amniotic fluid amnion membranes women with chorioamnionitis/intra-amniotic inflammation healthy controls. We also aimed elucidate involvement microRNA-548 (miR-548) regulating expression its function human epithelial cells (hAECs). A bioinformatics analysis predicted binding by...
Artificial intelligence has enabled the automated diagnosis of several cancer types. We aimed to develop and validate deep learning models that automatically classify cervical intraepithelial neoplasia (CIN) based on histological images. Microscopic images CIN3, CIN2, CIN1, non-neoplasm were obtained. The performances two pre-trained convolutional neural network (CNN) adopting DenseNet-161 EfficientNet-B7 architectures evaluated compared with those pathologists. dataset comprised 1106 from...
Even with the prolific clinical use of next-generation cancer therapeutics, many tumors remain unresponsive or become refractory to therapy, creating a medical need. In cancer, DCs are indispensable for T cell activation, so there is restriction on cytotoxic immunity if not present in sufficient numbers tumor and draining lymph nodes take up relevant antigens. To address this bottleneck, we developed therapeutic based albumin fused FMS-related tyrosine kinase 3 ligand (Alb-Flt3L) that...
Background: Multiple sclerosis (MS) is an immune-associated inflammatory disorder of the central nervous system and results in serious disability.Although many disease-modifying therapy drugs have been developed, these shown limited clinical efficacy some adverse effects previous studies, therefore, there has reasonable need for less harmful cost-effective therapeutics.Herein, we tested anti-inflammatory effect sulforaphane (SFN) a mouse model experimental autoimmune encephalomyelitis...
Malignant ovarian germ cell tumors are rare, and knowledge of their prognostic factors is limited, with little available randomized data. This study was conducted to evaluate the clinicopathologic characteristics malignant determine association primary treatment failure.The medical records 57 patients stages I IV tumor were retrospectively reviewed, treatment-related data collected analyzed.The median age at diagnosis 23.3 years (range: 8-65 years), follow-up period 108 months 48-205...
YouTube is one of the most popular open-access video-sharing websites, and it also used to obtain health care information. Cesarean delivery common major surgical intervention in many countries. Videos related cesarean have been uploaded YouTube. However, no study has explored overall quality videos on platform.The objective this was analyze content evaluate frequently viewed that are accessible YouTube.We searched for a total 18 terms by combining 6 retrieved from Google AdWords 3 c...
Many patients seek information online, including on social media, regarding various health topics. This study aimed to investigate whether YouTube videos endometriosis could be a useful source for the general population, surgical trainees, and specialists. A search was conducted December 26, 2021, using terms "endometriosis," "endometrioma," "endometriotic cyst." Videos were sorted by view count, 100 with highest counts chosen. After excluding 48 reasons, 52 included in final analysis. The...
The tailored radio frequency gradient echo (TRFGE) technique that has been used in venography (Cho et al., Magn. Reson. Med. 28, 25-38, 1992; Ro, Cho, 237, 1992) is applied to functional imaging. TRFGE the advantage it sensitive field created by susceptibility effect, thereby enhancing only signals from regions with local gradient. In addition, method insensitive in-flow especially arterial blood. latter further simplifies MRI data analysis. sequence is, therefore, suitable for MR imaging...
Abstract Background Renal allograft recipients are reported to have a higher incidence of malignancy than the general population. This single hospital-based study examined and clinicopathologic behavior uterine cervical carcinoma in renal transplant recipients. Methods Among 453 women receiving transplantation from January 1990 December 2008, 5 patients were diagnosed with carcinoma. Medical records these retrospectively reviewed, data collected analyzed. Results The was 58.1 out 100,000 per...
Our purpose was to provide the clinical advantages of laparoscopic approach compare vaginal in correcting uterine and vault prolapse.Between June 2007 2011, 174 women were admitted HUMC (Hallym University Medical Center) underwent pelvic reconstructive surgery for prolapsed uterus. Upon retrospective review medical records, patients who had symptoms organ Baden-Walker prolapse grade ≥ 2 selected divided into two groups as follows: group (n=120) (n=54). We compared results outcome by...