- Electrospun Nanofibers in Biomedical Applications
- Dendrimers and Hyperbranched Polymers
- Advanced Sensor and Energy Harvesting Materials
- Graphene and Nanomaterials Applications
- Transgenic Plants and Applications
- RNA Interference and Gene Delivery
- Nanoparticle-Based Drug Delivery
- Bone Tissue Engineering Materials
- Engineering Technology and Methodologies
- Plant tissue culture and regeneration
- Electrohydrodynamics and Fluid Dynamics
- 3D Printing in Biomedical Research
- Advanced biosensing and bioanalysis techniques
- Extracellular vesicles in disease
- Radiopharmaceutical Chemistry and Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Neuroscience and Neural Engineering
- Chemical Synthesis and Analysis
- Pluripotent Stem Cells Research
- Animal Virus Infections Studies
- SARS-CoV-2 detection and testing
- Dental Implant Techniques and Outcomes
- Toxin Mechanisms and Immunotoxins
- Polymer Synthesis and Characterization
- CRISPR and Genetic Engineering
Dalhousie University
2023-2024
University of Prince Edward Island
2023
Tehran University of Medical Sciences
2017-2021
Baqiyatallah University of Medical Sciences
2016
Pasteur Institute of Iran
2015
Salmonella enterica is considered one of the most common bacterial agent causes acute gastroenteritis and foodborne illness in humans worldwide. Antibiotic-resistant as a major problem Serovar. This study introduces new simple sensitive aptasensor based on chitosan (Chi)-electrospun carbon nanofibers (CNF) /gold nanoparticles (GNPs) decorated pencil graphite electrode (GE) novel platform for electrochemical detection A Salmonella-specific recognition aptamer ssDNA sequence was used...
Abstract Crosslinking is usually required to improve the mechanical properties and stability of collagen‐based scaffolds. Introducing exogenous crosslinks into collagen may however affect structure. Since architecture tied its functionality, it important study effect crosslinking select a method that preserves both structure properties. The objective this compare various methods on bioartificial tendon‐like materials (collagen multifilament bundles) fabricated by contact drawing. We examine...
Designing a unique theranostic biocompatible, biodegradable, and cost-effective agent which is easy to be synthesized as biohybrid material was the aim of this study. In matter, asparagine attached anionic linear globular dendrimer G2 (as negatively charged nanosized water soluble polymer that outweighs other traditionally used dendrimers) finally contrast (Gd 3+ ) loaded (which made complexes) in asparagine-dendrimer. Observations revealed that, addition successful colon cancer brain...
Coronaviruses (CoVs) are large ribonucleic acid (RNA) viruses causing primarily respiratory disease in humans. A novel human coronavirus, subsequently named middle east syndrome coronavirus (MERS-CoV), was first reported Saudi Arabia September of 2012. With increasing numbers infections and deaths from MERS-CoV, development a rapid reliable kit crucial to prevent further spread MERS-CoV.In this study, we present two real-time reverse-transcription polymerase chain reaction (rRT-PCR) assays...
Background: In spite of increasing number chemotherapeutic drugs, achieving chemotherapy drug with minimal side effects in cancer treatment is still a major challenge. Chemotherapy has an important role the non- Hodgkin's lymphoma cancer. Chlorambucil (CBL) lipophilic DNA alkylating having been administrated many cancers like leukemia but its use limited because chemical instability, low permeability cells and high toxicity. Keywords: Non-hodgkin's lymphoma, PLGA, chlorambucil,...
Dendrimers are one of the most appropriate nanocaries for imaging moieties in applications.The purpose this study was evalution cytotoxicity and inducing apoptosis dendrimers. This conducted order to investigate metastasis suppression effect dendrimer human breast MCF-7 cell line finding nanoparticle protein corona biological enviromental. Dendrimer assessed by MTT assay. The mRNA experession level KAI1 as a suppressor gene, Bax Pro- apoptotic Bcl-2 an anti-apoptotic gene GAPDH housekepping...
Alginate is among the most popular bioinks for 3D bioprinting because it biocompatible, biodegradable, and easily crosslinked using divalent cations. Here, we investigate addition of cellulose nanocrystals (CNCs) to an alginate-based bioink strengthen bioprinted structures. Using coaxial bioprinting, alginate strands were constructed with a core-sheath structure reinforced by CNCs within core. The resulted in increase storage modulus. Formulations containing more stable uniformity factors...
The purpose of this study was the investigation targeting potential 99mTc-Labeled dendrimer-phenylalanine conjugate for brain tumor SPECT imaging. L-Type amino acid transporters (LAT1) are highly expressed in blood-brain barrier as well cancer cells; thus, LAT1 using phenylalanine could improve sensitivity and specificity radiosynthesis nanocarrier. In study, dendrimer G2–phenylalanine synthesized characterized by Fourier transform infrared spectroscopy, atomic force microscopy, particle...
Abstract The design of new star-shaped dendrimers with ketoprofen and mefenamic acid at the periphery was achieved using divergent method. use cationic cyclopentadienyliron moieties coupled introduction to dendrimer allowed produce dendrimeric materials that possess antimicrobial anti-inflammatory activities. dendrimers' compositions were analyzed through FT-IR, 1H-NMR, 13C-NMR spectroscopic techniques. Furthermore, all synthesized exhibited exceptional thermal stability within 300 – 350oC...