A5107463035- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Acute Kidney Injury Research
- Renal Transplantation Outcomes and Treatments
- Liver Disease Diagnosis and Treatment
- Dialysis and Renal Disease Management
- Neonatal Respiratory Health Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Chronic Kidney Disease and Diabetes
- Central Venous Catheters and Hemodialysis
- Sexual function and dysfunction studies
- Drug-Induced Hepatotoxicity and Protection
- Bone health and treatments
- Sepsis Diagnosis and Treatment
- Diagnosis and Treatment of Venous Diseases
- Hormonal and reproductive studies
- Ion Channels and Receptors
- Childhood Cancer Survivors' Quality of Life
- Romani and Gypsy Studies
- Renal Diseases and Glomerulopathies
- Medical Imaging and Pathology Studies
- Congenital heart defects research
- Financial Literacy, Pension, Retirement Analysis
- Genomics and Rare Diseases
- Intestinal Malrotation and Obstruction Disorders
St. Vincent's University Hospital
2006-2023
University College Dublin
2008-2022
Centre Hospitalier de l’Université de Montréal
2021
University Hospital Limerick
2019-2020
National Maternity Hospital
2018
Midland Regional Hospital Mullingar
2014-2016
The Royal Free Hospital
2011-2015
University College London
2011-2015
Royal Free London NHS Foundation Trust
2014
King's College Hospital
2011
Despite the US Dialysis Outcome Quality Initiative )DOQI( guidelines, for various reasons, increasing numbers of end-stage renal disease patients are becoming dependent on cuffed haemodialysis catheters (HCs) chronic access. Their use is complicated by frequent failure due to thrombosis and catheter-related sepsis. In our unit, all HCs put in place radiology department.In a prospective study we looked at outcome over three-year period, during which time 573 consecutive were placed 336...
Background. Renal disease is a recognized complication of orthotopic liver transplantation (OLT). We aimed to determine the incidence all stages chronic kidney (CKD), as defined in Kidney Disease Outcomes Quality Initiative Guidelines. also wanted risk factors for development CKD and its impact on patient survival.
People with chronic kidney disease (CKD) experience high levels of psychological distress, which is associated higher mortality and adverse health outcomes. Little known about the rates a range mental difficulties or suicide attempts in people CKD.Individuals CKD (n = 268; age 18-94 years, mean 49.96 years) on haemodialysis 79), peritoneal dialysis 46), transplant recipients 84) who were not renal replacement therapy (RRT; n 59) recruited through Irish Kidney Association social media pages...
Paracetamol overdose can cause acute kidney injury (AKI) independent of its hepatotoxic effects. We aimed to determine the prevalence AKI (AKI Network definition) in those with paracetamol-induced hepatotoxicity, identify factors associated development, assess impact on outcomes patient survival and length stay proportion patients recovering renal function (estimated glomerular filtration rate > 60 mL/min) by time hospital discharge or transfer out.Between 2000 2007, admitted a tertiary...
Renal impairment post-liver transplant (LT) is often attributed to calcineurin inhibitors (CNIs). A renal biopsy can be a useful tool but may complicated in LT recipients. We aimed determine the clinical scenarios that prompted decision perform this patient population, assess histological findings and evaluate management survival outcome.Information on variables histology was extracted from single-centre prospectively compiled databases 1996 onwards.Over 2100 adults received an time period...
Abstract Purpose : Chronic allograft nephropathy (CAN) remains the leading cause of renal graft loss after first year following transplantation. This study aimed to identify novel urinary proteomic profiles, which could distinguish and predict CAN in susceptible individuals. Experimental design The included 34 transplant patients with histologically proven 36 normal function. High‐throughput profiles were generated from urine samples three different ProteinChip arrays by surface‐enhanced...
Obesity is a treatable risk factor for chronic kidney disease progression. We audited the reporting of body-mass index in nephrology outpatient clinics to establish characteristics individuals with obesity practice. Body-mass index, clinical information and biochemical measures were recorded patients attending between 3rd August, 2018 18th January, 2019. Inferential statistics Pearson correlations used investigate relationships type 2 diabetes, hypertension proteinuria. Mean ± SD BMI was...
Chronic kidney disease (CKD) is a common complication post-orthotopic liver transplantation (OLT). Development of CKD detected by monitoring serum urea and creatinine, however can occasionally be at an advanced stage before they become abnormal. Therefore, more accurate parameters are required. In order to identify novel biomarkers CKD, was obtained from 47 OLT recipients with (glomerular filtration rate <60 mL/min) 23 normal renal function >90 mL/min). Using the proteomic technique...
The use of novel kidney injury biomarkers has been shown to improve diagnostic assessment and prognostic prediction in various populations with acute (AKI), but their a standard clinical practice have rarely reported.We reported the implementation neutrophil gelatinase-associated lipocalin (NGAL) measurement for routine AKI workup patients receiving nephrology consultation tertiary academic centre. Specific focus was made on performance discriminate functional ("pre-renal") from intra-renal...
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The objective of this audit was to evaluate prescribing anti-coagulants for atrial fibrillation in haemodialysis patients St. Vincent's University Hospital. prevalence AF is between 8 and 34 percent on haemodialysis1. End stage renal disease were excluded from key trials evaluating direct-acting oral anticoagulants (DOACs) AF. Nevertheless when compared warfarin DOACs have similar or superior efficacy, less bleeding risk, more predictable pharmacokinetic pharmacodynamic properties2.
<h3>Introduction</h3> Ten to fifteen percent of small for gestational age (SGA) infants demonstrate failure catch-up growth. Haploinsufficiency the insulin-like growth factor-1 receptor (IGF1R) gene due monosomy 15q is an extremely rare cause with 16 cases reported in literature. We describe phenotype such a patient including biochemical findings, auxology and management. <h3>Case</h3> A three-year-old female global developmental delay autistic spectrum disorder was evaluated short stature....
<h3>Background</h3> Irish Travellers are a Roman Catholic endogamous minority group with origins dating back to the twelfth century. Latest figures estimate their numbers at 40,129 on Island of Ireland. The Romani people colloquially known as 'Roma Gypsies' an indo-Aryan ethnic originating from northern Indian subcontinent, also traditionally itinerant and estimated number 5000 in Ireland any one time. Often overlooked, nomadic races unique groups specific health needs <h3>Aims</h3> Our...