A5020652889- Neural dynamics and brain function
- Visual perception and processing mechanisms
- Functional Brain Connectivity Studies
- Visual Attention and Saliency Detection
- Congenital heart defects research
- Olfactory and Sensory Function Studies
- Neural and Behavioral Psychology Studies
- Genetics and Neurodevelopmental Disorders
- Autism Spectrum Disorder Research
- Muscle activation and electromyography studies
- Retinal Development and Disorders
- Neuroscience and Music Perception
- Transcranial Magnetic Stimulation Studies
- Face Recognition and Perception
- Undergraduate Neuroscience Education and Research
- Color perception and design
- Domain Adaptation and Few-Shot Learning
- Neuroscience, Education and Cognitive Function
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Neuroscience and Neural Engineering
- Aesthetic Perception and Analysis
- Advanced Chemical Sensor Technologies
- Vestibular and auditory disorders
- Hearing Loss and Rehabilitation
Boston Children's Hospital
2022-2024
Harvard University
2022-2024
KU Leuven
2018-2022
Harvard University Press
2022
VIB-KU Leuven Center for Brain & Disease Research
2022
Transcranial magnetic stimulation (TMS) can non-invasively modulate neural activity in humans. Despite three decades of research, the spatial extent cortical area activated by TMS is still controversial. Moreover, how interacts with task-related during motor behavior unknown. Here, we applied single-pulse over macaque parietal cortex while recording single-unit at various distances from center grasping. The TMS-induced activation remarkably restricted, affecting spiking single neurons an...
Summary Different theories explain how subjective experience arises from brain activity 1,2 . These have independently accrued evidence, yet, confirmation bias and dependence on design choices hamper progress in the field 3 Here, we present an open science adversarial collaboration which directly juxtaposes Integrated Information Theory (IIT) 4,5 Global Neuronal Workspace (GNWT) 6–10 , employing a theory-neutral consortium approach 11,12 We investigate neural correlates of content duration...
Copy-number variants of the CYFIP1 gene in humans have been linked to autism spectrum disorders (ASD) and schizophrenia (SCZ), two neuropsychiatric characterized by defects brain connectivity. Here, we show that plays an important role functional connectivity callosal functions. We find Cyfip1-heterozygous mice reduced white matter architecture, similar phenotypes found patients with ASD, SCZ other disorders. Cyfip1-deficient also present decreased myelination axons, altered presynaptic...
Abstract Different theories explain how subjective experience arises from brain activity1,2. These have independently accrued evidence, yet, confirmation bias and dependence on design choices hamper progress in the field3. Here, we present an open science adversarial collaboration which directly juxtaposes Integrated Information Theory (IIT)4,5 Global Neuronal Workspace (GNWT)6-10, employing a theory-neutral consortium approach11,12. We investigate neural correlates of content duration...
Understanding homologies and differences in auditory cortical processing human nonhuman primates is an essential step elucidating the neurobiology of speech language. Using fMRI responses to natural sounds, we investigated representation multiple acoustic features cortex awake macaques humans. Comparative analyses revealed homologous large-scale topographies not only for frequency but also temporal spectral modulations. In both species, posterior regions preferably encoded relatively fast...
Primates constantly explore their surroundings via saccadic eye movements that bring different parts of an image into high resolution. In addition to exploring new regions in the visual field, primates also make frequent return fixations, revisiting previously foveated locations. We systematically studied a total 44,328 fixations out 217,440 fixations. Return were ubiquitous across behavioral tasks, monkeys and humans, both when subjects viewed static images performed natural behaviors....
Abstract Neuroscience education is challenged by rapidly evolving technology and the development of interdisciplinary approaches for brain research. The Human Brain Project (HBP) Education Programme aimed to address need expertise in research equipping a new generation researchers with skills across neuroscience, medicine, information technology. Over its ten year duration, programme engaged over 1,300 experts attracted more than 5,500 participants from various scientific disciplines blended...
Electrophysiological evidence suggested primarily the involvement of middle temporal (MT) area in depth cue integration macaques, as opposed to human imaging data pinpointing V3B/kinetic occipital (V3B/KO). To clarify this conundrum, we decoded monkey functional MRI (fMRI) responses evoked by stimuli signaling near or far depths defined binocular disparity, relative motion, and their combination, compared results with those from an identical experiment previously performed humans. Responses...
Abstract Transcranial Magnetic Stimulation (TMS) can non-invasively modulate neural activity in humans. Despite three decades of research, the spatial extent cortical area activated by TMS is still controversial. Moreover, how interacts with task-related during motor behavior unknown. We applied single-pulse over macaque parietal cortex while recording single-unit at various distances from center stimulation grasping. The TMS-induced activation was remarkably restricted, affecting single...
SUMMARY Copy-number variants of the CYFIP1 gene in humans have been linked to Autism and Schizophrenia, two neuropsychiatric disorders characterized by defects brain connectivity. regulates molecular events underlying post-synaptic functions. Here, we show that plays an important role functional connectivity callosal In particular, find Cyfip1 heterozygous mice reduced white matter architecture, typically relating phenotypes found patients with Autism, Schizophrenia other disorders....
Event Abstract Back to Multisensory data-driven modeling of fMRI responses across primate species Marcelo Armendariz1, 2*, Dante Mantini2, 3, 4 and Wim Vanduffel1, 2, 5 1 Department Neurosciences, KU Leuven, Belgium 2 Leuven Brain Institute, 3 Movement Sciences, Leuven, IRCCS Fondazione Ospedale San Camillo, Italy Harvard Medical School, United States Humans experience the world via multiple sensory inputs that are hierarchically processed in brain. Identifying characterizing brain pathways...
Event Abstract Back to Encoding of natural sounds in human and monkey auditory cortex Marcelo Armendariz1, Julia Erb2, 3, Federico De Martino2, Elia Formisano2, 3 Wim Vanduffel1, 4, 5* 1 KU Leuven, Laboratory Neuro- Psychophysiology, Belgium 2 Maastricht University, Department Cognitive Neuroscience, Netherlands Brain Imaging Center, 4 Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, United States 5 Harvard Medical School, Radiology, Cortical processing...
Event Abstract Back to Integration of motion and disparity cues depth in monkey brain Marcelo Armendariz1*, Andrew Welchman2, Hiroshi Ban2 Wim Vanduffel1 1 KU Leuven, Neuroscience, Belgium 2 University Birmingham, School Psychology, United Kingdom Recognising interacting with objects depends on knowing the three-dimensional (3D) structure world around us. Estimating environment is a principal function visual system primates, enabling many key computations, such as segmentation, object...
As AI algorithms increasingly participate in daily activities that used to be the sole province of humans, we are inevitably called upon consider how much machines really like us. To address this question, turn Turing test and systematically benchmark current AIs their abilities imitate humans. We establish a methodology evaluate humans versus Turing-like tests representative set selected domains, parameters, variables. The experiments involved testing 769 human agents, 24 state-of-the-art...
Primates rely on hierarchically organized cortical areas in the ventral visual pathway to rapidly and accurately recognize objects. Previous work showed that linearly weighted summations of population activity across macaque inferior temporal (IT) cortex (final stage hierarchy) can sufficiently explain object confusion patterns. These “top-readout” decoding models posit downstream brain regions receiving input from IT drive categorization. However, such hypothetical (e.g., PFC) likely...
Primates constantly explore their surroundings via saccadic eye movements that bring different parts of an image into high resolution. In addition to exploring new regions in the visual field, primates also make frequent return fixations, revisiting previously foveated locations. We systematically studied a total 44,328 fixations out 217,440 fixations. Return were ubiquitous across behavioral tasks, monkeys and humans, both when subjects viewed static images performed natural behaviors....