A5085863196- Gut microbiota and health
- Tryptophan and brain disorders
- Diet and metabolism studies
- Bipolar Disorder and Treatment
- Mental Health Research Topics
- Gastrointestinal motility and disorders
- Schizophrenia research and treatment
- Nutritional Studies and Diet
- Eating Disorders and Behaviors
- Psychosomatic Disorders and Their Treatments
- Vagus Nerve Stimulation Research
- Health Policy Implementation Science
- Child Nutrition and Feeding Issues
- Electroconvulsive Therapy Studies
- Clinical practice guidelines implementation
- Obesity and Health Practices
- Ovarian function and disorders
- Obesity, Physical Activity, Diet
- Meta-analysis and systematic reviews
- Respiratory Support and Mechanisms
- Delphi Technique in Research
- Neuroendocrine regulation and behavior
- Complementary and Alternative Medicine Studies
- Primary Care and Health Outcomes
- Menopause: Health Impacts and Treatments
University College Cork
2019-2025
University of Minnesota
2010-2025
APC Microbiome Institute
2019-2023
Cork University Hospital
2023
Minnesota Department of Health
2023
Beaumont Hospital
2016
Beaumont Hospital, Royal Oak
2016
Botsford Hospital
2016
Beaumont Hospital, Dearborn
2016
Royal College of Surgeons in Ireland
2016
Abstract The microbiome-gut-brain axis plays a role in anxiety, the stress response and social development, is of growing interest neuropsychiatric conditions. gut microbiota shows compositional alterations variety psychiatric disorders including depression, generalised anxiety disorder (GAD), autism spectrum (ASD) schizophrenia but studies investigating microbiome (SAD) are very limited. Using whole-genome shotgun analysis 49 faecal samples (31 cases 18 sex- age-matched controls), we...
Objective: To assess pragmatic challenges faced when implementing, delivering, and sustaining models of integrated mental health intervention in primary care settings. Thirty percent patients with chronic medical conditions up to 80% those complexity have comorbidity, yet clinics rarely include onsite professionals only one eight receive evidence-based treatment. Integrating specialty into improves outcomes for common disorders, such as depression. Methods: We used key informant interviews...
Social anxiety disorder (SAD) is a crippling psychiatric characterized by intense fear or in social situations and their avoidance. However, the underlying biology of SAD unclear better treatments are needed. Recently, gut microbiota has emerged as key regulator both brain behaviour, especially those related to function. Moreover, increasing data supports role for immune function oxytocin signalling responses. To investigate whether plays causal modulating behaviours relevant SAD, we...
Introduction: The gut microbiota plays a role in gut–brain communication and can influence psychological functioning. Diet is one of the major determinants composition. impact unpasteurised dairy products on unknown. In this observational study, we investigated effect dietary change involving intake microbiome composition status participants undertaking residential 12-week cookery course an organic farm. Methods: Twenty-four completed study. majority food consumed during their stay...
Complex interventions are widely used in health care, public health, education, criminology, social work, business, and welfare. They have increasingly become the subject of systematic reviews challenging to effectively report. The Interventions Methods Workgroup developed an extension Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA-CI).Following EQUATOR Network guidance Meta-Analysis extensions, this Explanation Elaboration (EE) document accompanies PRISMA-CI...
Nutritional interventions have beneficial effects on certain psychiatric disorder symptomatology and common physical health comorbidities. However, studies evaluating nutritional literacy in mental professionals (MHP) are scarce. This study aimed to assess the across 52 countries. Surveys were distributed via colleagues professional societies. Data collected regarding self-reported general nutrition knowledge, education, learning opportunities, tendency recommend food supplements or...
BackgroundOnce a proposed topic has been identified for systematic review and undergone question formulation stage, protocol must be developed that specifies the scope research questions in detail outlines methodology conducting review.RationaleFramework modifications are often needed to accommodate increased complexity. We describe give examples of adaptations alternatives traditional analytic frameworks.DiscussionThis article identifies describes elements frameworks how they can adapted...
An awareness of the importance gut–brain axis in psychiatric disorders such as depression is increasing. The gut microbiome a key component this axis. Gut bacteria can communicate with brain through variety pathways including hypothalamic–pituitary–adrenal axis, immune modulation, tryptophan metabolism and production various neuroactive compounds. Patients depression, other mood anxiety disorders, show distinct compositional changes their profile, raising question about possible aetiological...
Background: An impairment of self and interpersonal functioning has an impact on coping strategies, regulation affect stress. Little is known so far about the personality in patients with bipolar disorder (BD). The aim this study to assess effects structure attachment BD symptom burden. Methods: Forty-six diagnosis were assessed by 12-item Operationalized Psychodynamic Diagnosis Structure Questionnaire (OPD-SQS), short version Experience Close Relationship-revised (ECR-R-D) Brief Symptom...
A functional reciprocity between the gut microbiome and vagal nerve activity has been suggested, however, human studies addressing this phenomenon are limited.Twenty-four-hour cardiac (CVA) was assessed from 73 female participants (aged 24.5 ± 4.3 years). Additionally, stool samples were subjected to 16SrRNA gene analysis (V1-V2). Quantitative Insights Into Microbial Ecology (QIIME) used analyse data. inflammatory parameters (such as CRP IL-6) derived serum samples.Daytime CVA correlated...