A5101441437- Reproductive Biology and Fertility
- Sperm and Testicular Function
- COVID-19 Clinical Research Studies
- Blood Coagulation and Thrombosis Mechanisms
- Salivary Gland Tumors Diagnosis and Treatment
- Advanced biosensing and bioanalysis techniques
- Thyroid and Parathyroid Surgery
- Sepsis Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Ovarian function and disorders
- Carbon and Quantum Dots Applications
- Land Use and Ecosystem Services
- Hepatitis B Virus Studies
- Iron Metabolism and Disorders
- Breast Lesions and Carcinomas
- Folate and B Vitamins Research
- Quantum Dots Synthesis And Properties
- Viral Infections and Outbreaks Research
- Remote Sensing and Land Use
- SARS-CoV-2 and COVID-19 Research
- Autophagy in Disease and Therapy
- Head and Neck Anomalies
- Environmental Changes in China
- Tissue Engineering and Regenerative Medicine
- RNA Interference and Gene Delivery
Fanjingshan National Nature Reserve
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2022
The University of Texas Medical Branch at Galveston
2018-2021
Shanghai University
2021
Ningxia Medical University
2014-2020
Qingdao University
2013-2018
Affiliated Hospital of Qingdao University
2018
Yinchuan First People's Hospital
2017
Ministry of Education of the People's Republic of China
2016
We determine if LBP contributes to the recovery from spermatogenic dysfunction in diabetic individuals.
Members of the family Filoviridae, including Ebola virus (EBOV) and Marburg (MARV), cause severe hemorrhagic fever in humans nonhuman primates. Given their high lethality, a comprehensive understanding filoviral pathogenesis is urgently needed. In present studies, we revealed that exchange protein directly activated by cAMP 1 (EPAC1) gene deletion protects vasculature ex vivo explants from EBOV infection. Importantly, pharmacological inhibition EPAC1 using EPAC-specific inhibitors (ESIs)...
To assess the value of ultrasonography (US) features for determining malignant potential complex cystic lesions.Seventy-nine lesions were reviewed retrospectively. They classified into four types according to US in type I, masses have a thick outer wall, internal septa, or both; II, are an intracystic with one more discrete solid mural within cyst; III, contain mixed and components at least 50% portion mass; IV, there predominantly (at 50%) eccentric central foci. Positive predictive values...
<title>Abstract</title> Land use change is a key factor affecting habitat quality. In order to reveal the impacts of urban land changes on quality, this paper uses city Zhongwei, China, as case study. Based data from 1980, 2000 and 2020, PLUS-InVEST coupled model was used predict assess quality Zhongwei. The results showed that 1980 areas construction woodland increased significantly, while water unused decreased slightly, other lands remained essentially unchanged. main factors such...
Valvular diseases are common health problems that strongly related to high morbidity and mortality; aortic valve allograft transplantation may be a promising way improve survival relieve symptoms. However, ideal tissue viability has not been observed with cryopreservation methods, which could lead apoptosis necrosis in cryopreserved tissue. It trehalose plays positive role by acting maintain cell structures protect cells from stress responses. In this study, we studied the effects of...
Coagulopathy is associated with both inflammation and infection, including infection the novel SARS-CoV-2 (COVID-19). Endothelial cells (ECs) fine tune hemostasis via cAMP-mediated secretion of von Willebrand factor (vWF), which promote process clot formation. The e xchange p rotein directly a ctivated by c AMP (EPAC) ubiquitously expressed intracellular cAMP receptor that plays key role in stabilizing ECs suppressing inflammation. To assess whether EPAC could regulate vWF release during...
Abstract The SARS-CoV-2 pandemic has inspired renewed interest in understanding the fundamental pathology of acute respiratory distress syndrome (ARDS) following infection because fatal COVID-19 cases are commonly linked to failure due ARDS. pathologic alteration known as diffuse alveolar damage endothelial and epithelial cells is a critical feature lung injury However, pathogenesis ARDS SRAS-CoV-2 remains largely unknown. In present study, we examined apoptosis post-mortem sections from...
Coagulopathy is associated with both inflammation and infection, including infections novel severe acute respiratory syndrome coronavirus-2, the causative agent infection of COVID-19. Clot formation promoted via cAMP-mediated secretion von Willebrand factor (vWF), which fine-tunes process hemostasis. The exchange protein directly activated by cAMP (EPAC) a ubiquitously expressed intracellular receptor that plays regulatory role in suppressing inflammation. To assess whether EPAC could...
In this study, the spatiotemporal expression of SerpinB11 in mouse testis from postnatal 1–60 d was checked, protein strongly localized intermediate spermatogonia, B-type spermatogonium, preleptotene spermatocyte, leptonema zygotene but weakly pachytene diplotene sphere sperm, and apoptotic sperm positive stained protein, localization cell cycle marker CDK4 meiosis SCP3 were investigated, colocalized spermatocyte. Taken together, these results suggested that might involved spermatogenesis apoptosis.