A5106485771- Gambling Behavior and Treatments
- Multiple Sclerosis Research Studies
- Psychometric Methodologies and Testing
- Nuclear Structure and Function
- Personality Disorders and Psychopathology
- Mental Health Research Topics
- Advanced Statistical Modeling Techniques
- Advanced Causal Inference Techniques
- Obsessive-Compulsive Spectrum Disorders
- Statistical Methods and Bayesian Inference
- RNA Research and Splicing
- Cognitive Abilities and Testing
- Eating Disorders and Behaviors
- Attention Deficit Hyperactivity Disorder
- Sexuality, Behavior, and Technology
- Peripheral Neuropathies and Disorders
- Systemic Sclerosis and Related Diseases
- Transcranial Magnetic Stimulation Studies
- Healthcare Systems and Practices
- Ginkgo biloba and Cashew Applications
- Health Systems, Economic Evaluations, Quality of Life
- Psychology of Social Influence
- Pharmaceutical Economics and Policy
- Schizophrenia research and treatment
- Pregnancy and Medication Impact
Peuplements végétaux et bioagresseurs en milieu tropical
2023
Écologie Marine Tropicale des Océans Pacifique et Indien
2023
Inserm
2019-2022
Centre Hospitalier Universitaire de La Réunion
2021-2022
Centre Hospitalier Saint-Denis
2021
Université de Rennes
2016-2020
Centre Hospitalier Universitaire de Rennes
2020
École des Hautes Études en Santé Publique
2015-2020
CIC Rennes
2020
Sciences, Philosophie, Histoire
2013-2019
In Europe, the prevalence of gambling disorders in general population ranges from 0.15 to 6.6%. Professional athletes are known for having risk factors addictive behaviors, such as young age or sensation seeking, though no study has yet tried evaluate and among this specific population. The goals were estimate gambling, problematic not, European professional explore that associated with practice problems athletes. A self-completion questionnaire was specifically designed study....
Background Craving is a core symptom of addictive disorders, such as pathological gambling for example. Over the last decade, several studies have assessed efficacy repetitive transcranial magnetic stimulation (rTMS) in addiction field, which triggers dorsolateral prefrontal cortex (DLPFC) to decrease craving. The STIMJEU study investigated whether single session low-frequency (LF, i.e., 1 Hz) rTMS applied right DLPFC reduced cue-induced craving sample treatment-seeking gamblers. Methods...
Compared to general population, pathological gamblers are 3.4 times more likely attempt suicide. Our objective was identify specific profiles of problem (PGs) with suicidal risk according sociodemographic, clinical and gambling characteristics. The PGs cohort, called "EVALJEU" , consists in the inclusion any new PG seeking treatment our Department. Patients underwent a semi-structured interview completed self-report questionnaires. "suicidal module" Mini International Psychiatric (MINI)...
Introduction The primary outcome of our study was to assess the links between level cognitive distortions and severity gambling disorder. We also aimed at assessing patient trajectories attention deficit hyperactivity disorder (ADHD). Materials methods population ( n = 628) comprised problem non-problem gamblers both sexes 18 65 years age, who reported on least one occasion during previous year. Data encompassed socio-demographic characteristics, habits, South Oaks Gambling Screen, Attitudes...
LMNA-linked familial partial lipodystrophy type 2 (FPLD2) leads to insulin resistance-associated metabolic complications and cardiovascular diseases. We aimed characterise the disease phenotype in a cohort of patients carrying an LMNA founder variant.We collected clinical biological data from monoallelic or biallelic p.(Thr655Asnfs*49) variant (n = 65 13, respectively) 19 non-affected relative controls followed-up Reunion Island Lipodystrophy Competence Centre, France.Two-thirds with FPLD2...
Patient-reported outcomes (PRO) have gained importance in clinical and epidemiological research aim at assessing quality of life, anxiety or fatigue for instance. Item Response Theory (IRT) models are increasingly used to validate analyse PRO. Such relate observed variables a latent variable (unobservable variable) which is commonly assumed be normally distributed. A priori sample size determination important obtain adequately powered studies determine clinically changes In previous...
Most of the knowledge about people with multiple sclerosis (PwMS) in France comes from cohorts, which may suffer recruitment bias or unique registry located Lorraine, East France.To describe use care French population PwMS, over 2010-2015.All PwMS national health data system (97% general covered) were included. Demographics, and described (visits practitioners (GPs), neurologists, nurses, physiotherapists hospitalisations). A focus on neurological follow-up was also conducted.A total 112,415...
Concerns about body shape and weight are core diagnostic criteria for eating disorders although intensity varies between patients. Few studies have focused on the clinical differences relative to of these concerns. Nonetheless, they might a prognostic value. This study was aimed at identifying characteristics associated with marked concerns in patients an disorder. Data collected from systematic standardized assessment outpatients seeking treatment our department disorders. Only female...
When assessing change in patient-reported outcomes, the meaning patients’ self-evaluations of target construct is likely to over time. Therefore, methods evaluating longitudinal measurement non-invariance or response shift at item-level were proposed, based on structural equation modelling item theory. Methods coming from Rasch theory could also be valuable. The lack evaluation these approaches prevents determining best strategy adopt. A simulation study was performed compare and evaluate...
Background and aims Gambling disorder-related illegal acts (GDRIA) are often crucial events for gamblers and/or their entourage. This study was designed to determine the predictive factors of GDRIA. Methods Participants were 372 reporting at least three DSM-IV-TR (American Psychiatric Association, 2000) criteria. They assessed on basis sociodemographic characteristics, gambling-related personality profile, psychiatric comorbidities. A multiple logistic regression performed identify relevant...
Statistical modeling conference on the quality of life measurements French National Platform Quality Life and Cancer Faculty Science in Luminy, Marseille, France, 12-13 September 2013 The statistical team Mathematical Institute Luminy undertook a successful first addressing challenges measuring field oncology. More than 15 presentations were made over 2-day period by Sciences Luminy. managed to assemble participants from different disciplines, such as mathematics statistics, public health,...
To describe pregnancies exposed to teriflunomide (TERIF) in women with multiple sclerosis (MS) France over the period 2014-2016.All 15- 49-year-old MS national health insurance database were included. Pregnancies that had started between August 2014 and March 2016 identified from their outcomes. Three groups according treatment exposure compared: TERIF, interferons (IFNs) or glatiramer acetate, no medication.Among 44,008 followed 24.5 months on average, 2,639 identified. There 1,538 (58.3%)...
Patient-reported outcomes (PRO) are important as endpoints in clinical trials and epidemiological studies. Guidelines for the development of PRO instruments analysis data have emphasized need to report methods used sample size planning. The Raschpower procedure has been proposed power determination comparison PROs cross-sectional studies comparing two groups patients when an item reponse model, Rasch is intended be analysis. test group effect using requires several parameters fixed at...
The transition to metabolically unhealthy obesity (MUO) is driven by the limited expandability of adipose tissue (AT). Familial Partial Lipodystrophy type 2 (FPLD2) an alternative model for AT dysfunction that suitable comparison with obesity. While MUO associated low-grade systemic inflammation, studies inflammation in FPLD2 have yielded inconsistent results. Consequently, markers between and great interest better understand pathophysiological defects FPLD2.To compare levels inflammatory...
Il aura fallu attendre 2010 pour que soit menée en France la première étude de prévalence des troubles liés à pratique jeux hasard et d’argent [1]. Si cette enquête a indiqué les problèmes jeu touchaient environ 1,3 % population adulte, elle ne décrivait partiellement caractéristiques associées. est cependant essentiel disposer d’informations pouvant expliquer qu’une récréative devienne hors contrôle. L’étude JEU ambition. Impliquant 7 centres hospitaliers français, débuté 2009 permis...
Abstract Background Multiple sclerosis (MS) is a chronic neurological disease affecting about 100,000 persons in France. Disease management mainly supervised by the neurologist, supported general practitioner (GP). The complexity of disease, due to variety symptoms as well recent changes therapeutic arsenal, requires both high level expertise and coordination between different health care providers. To face this challenge, integrated coordinated network services “MS expert centers” have been...
Mental disorders (MDs) in multiple sclerosis (MS) patients decreases treatment adherence and quality of life, increases the risk disability progression care consumption.This study was to assess prevalence MDs MS compared with healthy controls (HC) French general population rheumatoid arthritis (RA) patients.The 2015 for patients, RA estimated using a random population-based data sample from 'National Inter-Scheme Information System on Health Insurance' 2011-2015 period. Two control groups...