A5090202240- Neurotransmitter Receptor Influence on Behavior
- Memory and Neural Mechanisms
- Psychedelics and Drug Studies
- Receptor Mechanisms and Signaling
- Biochemical Analysis and Sensing Techniques
- Morinda citrifolia extract uses
- Stress Responses and Cortisol
- Attention Deficit Hyperactivity Disorder
- Tryptophan and brain disorders
- Alcohol Consumption and Health Effects
- Microbial Metabolites in Food Biotechnology
- Neuroscience and Neuropharmacology Research
- Chemical synthesis and alkaloids
- Probiotics and Fermented Foods
- Medicinal Plants and Neuroprotection
- Gut microbiota and health
- Cannabis and Cannabinoid Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Olfactory and Sensory Function Studies
Universidade Estadual de Santa Cruz
2018-2021
Psychobiotics correspond to a class of probiotics, mainly the genus Lactobacillus and Bifidobacterium, capable producing neuroactive substances, such as γ-aminobutyric acid (GABA) serotonin, which exert effects on brain-gut axis. Evidence suggests that psychobiotics can have beneficial effect mood, anxiety cognition. The present study evaluated chronic administration two new strains plantarum, L. plantarum 286 (Lp 286) 81 81) isolated from fermentation cocoa (Theobroma cacao L.) cupuaçu...
Ayahuasca is a hallucinogenic beverage produced from the decoction of Banisteriopsis caapi (Bc) and Psychotria viridis (Pv), β-carboline- N,N-dimethyltryptamine(DMT)-containing plants, respectively. Accumulating evidence suggests that ayahuasca may have therapeutic effects on ethanol abuse. It not known, however, whether its are dependent presence DMT or if non-DMT-containing components would effects. The aim present study was to investigate rewarding properties (30, 100 300 mg/kg, orally),...
Evidence suggests that aripiprazole, a partial dopamine D2 and serotonin 5-HT1A receptor agonist 5-HT2A antagonist, show significant efficacy in reducing alcohol use. We have previously demonstrated treatment with aripiprazole blocked the reinstatement of cocaine-induced behavioral sensitization context-dependent manner, suggesting environment may modulate therapeutic effects aripiprazole. The present study aimed to evaluate on ethanol-induced conditioned place preference female mice, role...
Ibogaine is a psychedelic extracted from the plant Tabernanthe iboga Baill. (Apocynaceae) , natural Africa, and has been proposed as potential treatment for substance use disorders. In animal models, ibogaine reduces ethanol self-administration. However, no study to date investigated effects of on ethanol-induced conditioned place preference (CPP). The present aimed investigate repeated with reinstatement CPP in male mice. rewarding (1.8 g/kg, i. p.) or (10 30 mg/kg, p. o.) were using model....
Contradictory findings suggest that the behavioral and abuse-related effects of ethanol are mediated by its action at α1 subunit-containing GABAA (α1GABAA) receptors. In present study, we investigated a sub-chronic post-ethanol administration treatment with zolpidem, an α1-preferring positive allosteric modulator receptors, on subsequent expression ethanol-induced sensitization in mice. Animals received (1.8 g/kg, ip) or saline treatments every other day for 15 days (8 sessions) were...