A5031501754- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- RNA modifications and cancer
- Gut microbiota and health
- Dietary Effects on Health
- Epigenetics and DNA Methylation
- Gastrointestinal motility and disorders
- Cardiovascular Disease and Adiposity
- Extracellular vesicles in disease
- Clostridium difficile and Clostridium perfringens research
- Cancer-related gene regulation
- Diet, Metabolism, and Disease
Hospital de Clínicas de Porto Alegre
2023-2024
Universidade Federal do Rio Grande do Sul
2023-2024
BACKGROUND Prevalence of hepatocellular carcinoma (HCC) is increasing, especially in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). AIM To investigate rifaximin (RIF) effects on epigenetic/autophagy markers animals. METHODS Adult Sprague-Dawley rats were randomly assigned (n = 8, each) and treated from 5-16 wk: Control [standard diet, water plus gavage vehicle (Veh)], HCC [high-fat choline deficient diet (HFCD), diethylnitrosamine (DEN) drinking Veh gavage],...
Extracellular vesicles (EVs) are promising as a biomarker of metabolic dysfunction associated steatotic liver disease (MASLD). The objective is to study EVs and their involvement in MASLD concerning the disease's pathogenesis progression characteristics.
Genetic and epigenetic alterations are related to metabolic dysfunction-associated steatotic liver disease (MASLD) pathogenesis.