A5052919207- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Drug-Induced Hepatotoxicity and Protection
- Liver Diseases and Immunity
- Diet, Metabolism, and Disease
- RNA modifications and cancer
- Bioactive Compounds and Antitumor Agents
- Sesquiterpenes and Asteraceae Studies
- Cancer-related gene regulation
- Inflammasome and immune disorders
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Tannin, Tannase and Anticancer Activities
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Biochemical and Molecular Research
- Pleural and Pulmonary Diseases
- Plant chemical constituents analysis
- Synthesis and Reactions of Organic Compounds
- Synthesis and Biological Evaluation
- Cancer, Lipids, and Metabolism
- interferon and immune responses
- Cancer, Hypoxia, and Metabolism
- Ultrasound and Hyperthermia Applications
- Curcumin's Biomedical Applications
- Tendon Structure and Treatment
Pontifícia Universidade Católica do Rio Grande do Sul
2013-2025
Michigan State University
2025
Hospital de Clínicas de Porto Alegre
2024
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2023
Portal hypertension (PH) is a frequent and severe clinical syndrome associated with chronic liver disease. Considering the mechanobiological effects of hydrostatic pressure shear stress on endothelial cells, we hypothesised that PH might influence phenotype sinusoidal cells (LSECs) during disease progression. The aim this study was to investigate increased hydrodynamic LSECs identify endothelial-derived biomarkers PH.Primary were cultured under normal or within pathophysiological range (1...
Process-based cropping systems models (CSMs) are key components of measurement, monitoring, reporting, and verification (MMRV) frameworks carbon markets, but their application suffers from model-specific differences that keep any one model working well across all combinations soils, climates, crops, agronomic practices at varying scales. Multi-model ensemble (MME), successfully used to quantify soil, management climate impact on crop productivity, provide an opportunity better estimate...
BACKGROUND Prevalence of hepatocellular carcinoma (HCC) is increasing, especially in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). AIM To investigate rifaximin (RIF) effects on epigenetic/autophagy markers animals. METHODS Adult Sprague-Dawley rats were randomly assigned (n = 8, each) and treated from 5-16 wk: Control [standard diet, water plus gavage vehicle (Veh)], HCC [high-fat choline deficient diet (HFCD), diethylnitrosamine (DEN) drinking Veh gavage],...
Acute lung injury (ALI) is an inflammatory process, and has high incidence mortality. ALI the acute respiratory distress syndrome are two common complications worldwide that result in failure, sepsis, death. Pro-inflammatory substances, such as cytokines chemokines, responsible for activating body's defense mechanisms usually mediate processes. Therefore, research of substances decrease uncontrolled response organism seen potential patients with ALI. Octyl gallate (OG) a phenolic compound...
(+)-Catechin is a type of catechin present in large amounts açaí fruits and cocoa seeds. Besides its antioxidant anti-inflammatory activities, little known about effects the liver, especially during hepatic fibrosis. We report here (+)-catechin on stellate cells. induced quiescent phenotype GRX cells, along with an increase lipid droplets. Proliferator-activated receptor γ mRNA expression was upregulated, whereas I collagen downregulated. Pro-inflammatory cytokines were not influenced by...
Octyl gallate (OG) is an antioxidant commonly used in food, although there no definition of its acceptable daily intake. There are reports vitro and vivo showing that food additives drugs can alter lipid metabolism. Lipid droplet accumulation hepatic cells one the main findings unregulated metabolism strongly related to development nonalcoholic fatty liver disease (NAFLD). In this study, we investigated effects OG on hepatocellular carcinoma cell line (HepG2). The results have shown, for...