Kelly Goulart Lima

ORCID: 0000-0002-1912-2150
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Cancer, Hypoxia, and Metabolism
  • Tannin, Tannase and Anticancer Activities
  • Liver physiology and pathology
  • Cancer, Lipids, and Metabolism
  • Diet, Metabolism, and Disease
  • Diabetes Treatment and Management
  • Metabolism, Diabetes, and Cancer
  • Natural Compounds in Disease Treatment
  • Pleural and Pulmonary Diseases
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Autophagy in Disease and Therapy
  • Public Health in Brazil
  • Genomics, phytochemicals, and oxidative stress
  • Neonatal and Maternal Infections
  • Streptococcal Infections and Treatments
  • Metabolomics and Mass Spectrometry Studies
  • Biochemical and Molecular Research
  • Plant tissue culture and regeneration
  • Surgical site infection prevention
  • Pancreatic function and diabetes
  • Antimicrobial Resistance in Staphylococcus
  • PI3K/AKT/mTOR signaling in cancer
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Cholesterol and Lipid Metabolism

Pontifícia Universidade Católica do Rio Grande do Sul
2016-2023

Universidade de São Paulo
2020

It has been reported that glucagon-like peptide-1 (GLP-1) agents have associated with both the increased risk of cancer and inhibition tumor growth metastases. The aim this study is to evaluate effect liraglutide on hepatocellular carcinoma cells - HepG2. Cytometry was used mechanism related decreased cell proliferation. Nuclear staining morphometric analysis were also verify process taking place after treatment liraglutide, in order better understand mechanism, TGF-β1 performed. HepG2...

10.1016/j.ejphar.2017.05.015 article EN publisher-specific-oa European Journal of Pharmacology 2017-05-11

The incidence of hepatocellular carcinoma (HCC) keeps rising year by year, and became the second leading cause cancer-related death. Some studies have found that liraglutide, a GLP-1 analog, may decrease tumor cells proliferation. Due to this, aim this work is investigate antiproliferative potential exenatide, another analog. Cell proliferation was assessed direct count with Trypan blue dye exclusion. Flow cytometry used determinate autophagy nuclear staining. Morphometric analysis verify...

10.17179/excli2019-1415 article EN PubMed 2019-01-01

Octyl gallate (OG) is an antioxidant commonly used in food, although there no definition of its acceptable daily intake. There are reports vitro and vivo showing that food additives drugs can alter lipid metabolism. Lipid droplet accumulation hepatic cells one the main findings unregulated metabolism strongly related to development nonalcoholic fatty liver disease (NAFLD). In this study, we investigated effects OG on hepatocellular carcinoma cell line (HepG2). The results have shown, for...

10.17179/excli2020-2214 article EN EXCLI journal 2020-07-06

Objective: To describe the antimicrobial resistance profile of strains isolated from neonates with septicemia undergoing vancomycin treatment, to determine agreement treatment guideline and blood cultures, assess presence acute kidney injury (AKI) clinical outcome in a hospital Brazil. Methods: A total 51 newborns treated were studied period January December 2017. Treatment assessment was verified by compliance Rational Use Insurance Policy Antibiotics Neonatology culture. The AKI based on...

10.30968/rbfhss.2020.113.0472 article EN cc-by-nc-nd Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde 2020-09-21

Abstract: This study aimed to identify the pattern of antimicrobial use in a unit and orthopedic surgical clinic medium-sized hospital Mato Grosso. The based analysis 500 medical charts filling out forms previously prepared from Regional Hospital Sorriso, between March April 2012, after approval project by CEP Julio Muller University (Protocol No. 219/2011). It was observed that 69% (345) sample were male, with ages ranging 18 112 years. In all can observe prescription antibiotics, most...

10.36560/20201319 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2013-03-01
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