A5059520764- Plant Stress Responses and Tolerance
- Plant nutrient uptake and metabolism
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Plant responses to water stress
- Protein Degradation and Inhibitors
- Ubiquitin and proteasome pathways
- Plant Parasitism and Resistance
- Plant and animal studies
- Genetic and phenotypic traits in livestock
- Multiple Myeloma Research and Treatments
- Genetic diversity and population structure
- Plant Gene Expression Analysis
- Agronomic Practices and Intercropping Systems
- Plant Water Relations and Carbon Dynamics
- Biofuel production and bioconversion
- Histone Deacetylase Inhibitors Research
- Genetic Mapping and Diversity in Plants and Animals
- Transgenic Plants and Applications
- Enzyme Catalysis and Immobilization
- Ecology and Vegetation Dynamics Studies
- Light effects on plants
- Aluminum toxicity and tolerance in plants and animals
- Peptidase Inhibition and Analysis
- Plant Reproductive Biology
The University of Texas MD Anderson Cancer Center
2023-2024
The University of Texas at Austin
2019-2023
Institute of Plant and Microbial Biology, Academia Sinica
2012-2021
National Chung Hsing University
2012-2013
National Taipei University
2013
Academia Sinica
2013
Abstract Six Arabidopsis (Arabidopsis thaliana) clade A protein phosphatase 2Cs (PP2Cs) have established abscisic acid (ABA) signaling roles; however, phenotypic roles of the remaining three “HAI” PP2Cs, Highly ABA-Induced1 (HAI1), AKT1-Interacting PP2C1/HAI2, and HAI3, remained unclear. HAI PP2C mutants had enhanced proline osmoregulatory solute accumulation at low water potential, while other PP2Cs no or lesser effect on these drought resistance traits. hai1-2 also increased expression...
Drought-induced proline accumulation observed in many plant species has led to the hypothesis that further increases would promote drought tolerance. Here we discuss both previous and new data showing metabolism turnover, rather than just accumulation, functions maintain growth during water limitation. Mutants of Δ (1)-Pyrroline-5-Carboxylate Synthetase1 (P5CS1) Proline Dehydrogenase1 (PDH1), key enzymes synthesis catabolism respectively, have similar reductions controlled soil drying. Such...
The clade A protein phosphatase 2C Highly ABA-Induced 1 (HAI1) plays an important role in stress signaling, yet little information is available on HAI1-regulated phosphoproteins. Quantitative phosphoproteomics identified phosphopeptides of increased abundance hai1-2 unstressed plants and exposed to low-water potential (drought) stress. identity localization the phosphoproteins as well enrichment specific phosphorylation motifs indicated that these sites may be regulated directly by HAI1 or...
Plant growth is coordinated with environmental factors, including water availability during times of drought. Microtubules influence cell expansion; however, the mechanisms by which signals impinge upon microtubule organization and whether microtubule-related factors limit drought remains unclear. We found that three
Host–parasite coevolution can maintain high levels of genetic diversity in traits involved species interactions. In many systems, host exploited by parasites are constrained use other functions, leading to complex selective pressures across space and time. Here, we study genome-wide variation the staple crop Sorghum bicolor (L.) Moench its association with parasitic weed Striga hermonthica (Delile) Benth., a major constraint food security Africa. We hypothesize that geographic selection...
Abstract Little is known about cytoplasmic osmoregulatory mechanisms in plants, and even less understood how the osmotic properties of cytoplasm organelles are coordinately regulated. We have previously shown that Arabidopsis (Arabidopsis thaliana) plants lacking functional versions plastid-localized mechanosensitive ion channels Mechanosensitive Channel Small Conductance-Like2 (MSL2) MSL3 contain leaf epidermal plastids under hypoosmotic stress, during normal growth development. Here, we...
Water-use efficiency (WUE) is the ratio of biomass produced per unit water consumed; thus, it can be altered by genetic factors that affect either side ratio. In present study, we exploited natural variation for WUE to discover loci affecting accumulation or use as WUE. Genome-wide association studies (GWAS) using integrated measured through carbon isotope discrimination (δ13C) Arabidopsis thaliana accessions identified genomic regions associated with Reverse analysis 70 candidate genes...
Several studies have used short term dehydration, osmotic stress or Abscisic Acid (ABA) treatments to identify the initial protein phosphorylation-dephosphorylation responses drought and low water potential ABA treatments. However, longer acclimation leads altered expression of many kinases phosphatases suggesting that it may also produce unique changes in phosphoproteome composition. To get a better overview state drought-related phosphoproteomics investigate this question versus...
A novel, alkali-tolerant halophilic bacterium-OKH with an ability to produce extracellular halophilic, alkali-tolerant, organic solvent stable, and moderately thermostable xylanase was isolated from salt salterns of Mithapur region, Gujarat, India. Identification the bacterium done based upon biochemical tests 16S rRNA sequence. Maximum production achieved at pH 9.0 37°C temperature in medium containing 15% NaCl 1% (w/v) corn cobs. Sugarcane bagasse wheat straw also induce when used as...
Abstract During moderate severity drought and low water potential (ψw) stress, poorly understood signaling mechanisms restrict both meristem cell division subsequent expansion. We found that the Arabidopsis thaliana Clade E Growth-Regulating 2 (EGR2) protein phosphatase Microtubule-Associated Stress Protein 1 (MASP1) differed in their stoichiometry of accumulation across root had opposing effects on activity at ψw. Ectopic MASP1 or EGR expression increased decreased, respectively, size...
Abstract Transcriptional reprogramming plays a key role in drought stress responses, preceding the onset of morphological and physiological acclimation. The best-characterized signal regulating gene expression response to is phytohormone abscisic acid (ABA). ABA-regulated expression, biosynthesis signaling are highly organized diurnal cycle, so that traits occur at appropriate time day. mechanisms underpin such diel oscillations ABA signals poorly characterized. Here we uncover GIGANTEA (GI)...
Despite recent advances in therapeutic treatments, multiple myeloma (MM) remains an incurable malignancy. Epigenetic factors contribute to the initiation, progression, relapse, and clonal heterogeneity MM, but our knowledge on epigenetic mechanisms underlying MM development is far from complete. The SAGA complex serves as a coactivator transcription catalyzes acetylation deubiquitylation. Analyses of data sets Cancer Dependency Map Project revealed that many components are selective...
Soil salinity can negatively impact plants growth, development and fitness. Natural plant populations restricted to coastal environments may evolve in response saline habitats therefore provide insights into the process of adaptation. We investigated growth physiological responses inland Panicum hallii experimental treatments. Coastal genotypes demonstrated less reduction superior ion homeostasis compared conditions, supporting a hypothesis local identified several QTL associated with...
Abstract The Clade A protein phosphatase 2C Highly ABA-Induced 1 (HAI1) plays an important role in stress signaling yet little information is available on HAI1-regulated phosphoproteins. Quantitative phosphoproteomics identified phosphopeptides of increased abundance hai1-2 unstressed plants and exposed to low water potential (drought) stress. identity localization the phosphoproteins as well enrichment specific phosphorylation motifs indicated that these sites may be regulated directly by...
The evolution of gene expression is thought to be an important mechanism local adaptation and ecological speciation. Gene divergence occurs through the cis- polymorphisms more widespread effects driven by trans-regulatory factors. Here, we explore sequence in a large sample Panicum hallii accessions encompassing species range using reciprocal transplantation experiment. We observed genotype transplant site drivers divergence, with limited number genes exhibiting genotype-by-site...
ABSTRACT Host-parasite coevolution can maintain high levels of genetic diversity in traits involved species interactions. In many systems, host exploited by parasites are constrained use other functions, leading to complex selective pressures across space and time. Here, we study genome-wide variation the staple crop Sorghum bicolor (L.) Moench its association with parasitic weed Striga hermonthica (Delile) Benth., a major constraint food security Africa. We hypothesize that geographic...
Abstract Despite recent advances in therapeutic treatments, multiple myeloma (MM) remains an incurable malignancy. Epigenetic factors contribute to the initiation, progression, relapse, and clonal heterogeneity MM, but our knowledge on epigenetic mechanisms underlying MM development is far from complete. The SAGA complex serves as a coactivator transcription catalyzes acetylation deubiquitylation. Analyses of datasets Cancer Dependency Map Project revealed many components are selective...
Abstract The evolution of gene expression is thought to be an important mechanism local adaptation and ecological speciation. Gene divergence occurs through the cis-polymorphisms more widespread effects driven by trans-regulatory factors. Lovell et al. (2018) studied between two ecotypes Panicum hallii using quantitative trait loci (eQTL) analyses discovered a pre-dominance cis several divergences. Here, we explore sequence in large sample P. accessions encompassing species range reciprocal...
Abstract Water use efficiency (WUE) is the ratio of biomass gained per unit water consumed; thus, it can be altered by genetic factors that affect either side ratio. In present study, we exploited natural variation for WUE as an unbiased approach to discover loci affecting accumulation or WUE. Genome-wide association (GWAS) analysis using integrated measured through carbon isotope discrimination (δ 13 C) Arabidopsis thaliana accessions identified genomic regions associated with Reverse 70...
Abstract During moderate severity drought and low water potential (ψ w ) stress, poorly understood signaling mechanisms restrict both meristem cell division subsequent expansion. We found that the Clade E Growth-Regulating 2 ( EGR2 protein phosphatase Microtubule Associated Stress Protein 1 MASP1 differed in their stoichiometry of expression across root had opposing effects on activity at ψ . Ectopic or EGR increased decreased, respectively, size elongation during stress. This, along with...